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Baseline FIB‐4 May Be a Risk Factor of Recurrence After SBRT in Patients With HBV‐Related Small HCC
Published 2025-01-01Get full text
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6682
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6683
Mycoplasma pneumoniae Infection in Children Is a Risk Factor for Developing Allergic Diseases
Published 2014-01-01Get full text
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6684
Field Experiment Research of the Polycystic Aeration Bolt: Model Design and Anchorage Mechanism
Published 2021-01-01Get full text
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6685
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6686
A Game Mechanism of Individual Value Decision-Making Based on SVO Differences
Published 2020-01-01Get full text
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6687
Research and application of big data platform technology based on multi-centre collaborative computing
Published 2024-05-01Get full text
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6688
Advances in Nonlinear Complexity Analysis for Partial Differential Equations
Published 2013-01-01Get full text
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6689
Response of Rice Nitrogen Physiology to High Nighttime Temperature during Vegetative Stage
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6690
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6695
Risk Factors for Persistent or Recurrent Central Serous Chorioretinopathy
Published 2019-01-01Get full text
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6696
UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research
Published 2025-01-01“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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6697
Failure Analysis of Corrosion-Induced Perforation in B10 Copper-Nickel Alloy Pipelines
Published 2024-12-01Get full text
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6698
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6699
Alpha-glucosidase inhibitor decreases the risk of colorectal adenoma in the aged with Type 2 diabetes
Published 2025-01-01Get full text
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