Synthesis, Characterization, X-Ray Crystallography, and Antileishmanial Activities of N-Linked and O-Linked Glycopyranosides by Haroon ur Rashid, Sher Wali Khan, Momin Khan, Akhtar Nadhman, Noor Rehman, Muhammad Tariq, Sammer Yousuf

Get full text

Structural Characterization of B-DNA d(CGTGAATTCACG)₂ in Complex with the Specific Minor Groove Binding Fluorescent Marker Hoechst 33342 by Hristina Sbirkova-Dimitrova, Rusi Rusew, Hristo Gerginov, Annie Heroux, Boris L. Shivachev

Subjects: Get full text

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography by Adel S. El-Azab, Nasr Y. Khalil, Alaa A.-M. Abdel-Aziz

Get full text

Synthesis and Conformational Analysis of Sterically Congested (4R)-(−)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations by Ibrahim A. Al-Swaidan, Adel S. El-Azab, Amer M. Alanazi, Alaa A.-M. Abdel-Aziz

Get full text

Agonistic anti-NKG2D antibody structure reveals unique stoichiometry and epitope compared to natural ligands by Daniel Fallon, Ching-Shin Huang, Jingya Ma, Christopher Morgan, Zhaohui Sunny Zhou

Subjects: Get full text

Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1 by Pauline Malinge, Xavier Chauchet, Jérémie Bourguignon, Nicolas Bosson, Sébastien Calloud, Tereza Bautzova, Marie Borlet, Mette Laursen, Vinardas Kelpsas, Nadia Rose, Franck Gueneau, Ulla Ravn, Giovanni Magistrelli, Nicolas Fischer

Subjects: Get full text

Crystal Structures of <span style="font-variant: small-caps">d</span>-Lyxono-1,4-lactone and Its <i>O</i>-Tosyl Derivative by Anna Sosnowska, Jarosław Chojnacki, Justyna Samaszko-Fiertek, Janusz Madaj, Barbara Dmochowska

Subjects: Get full text

L’école de cristallographie de Nancy : un hommage by Welter, Richard

“…They are specifically three “great” deceased teachers who marked my scientific formation and allowed me to be well prepared in the large field of X-ray crystallography.In this article, I want to pay tribute to the Professors Yves Dusausoy, Jean Protas and Niels Hansen and show, on a few easy examples, the relevance of their respective teachings.…”
Get full text

Cyclization Reactions Involving 2-Aminoarenetellurols and Derivatives of α,β-Unsaturated Carboxylic Acids by Jayna A. Patel, Aundrea M. Lee, Donna V. Franklin, Frank R. Fronczek, Thomas Junk

“…Selected compounds were characterized by X-ray crystallography. The present work offers access to previously unexplored organotellurium heterocycles.…”
Get full text

Structure-based insights into fluorogenic RNA aptamers by Song Qianqian, Tai Xiaoqing, Ren Qianyu, Ren Aiming

“…To date, a variety of tertiary structures of fluorogenic RNA aptamers have been determined using X-ray crystallography or NMR spectroscopy. …”
Get full text

DIMETHYL N-CYANODITHIOIMINOCARBONATE AND TRIPHENYLPHOSPHINE OXIDE METAL HALIDE COMPLEXES: MOLECULAR CRYSTAL ELUCIDATION by MOUHAMADOU BIRAME DIOP, MODOU SARR, LIBASSE DIOP, ALLEN G. OLIVER, DAVID HUGHES

“… Two MX2 (M = Ni, Zn; X = Cl, Br) dimethyl N-cyanodithioiminocarbonate compounds and one CrCl2 triphenylphosphine oxide complex were isolated and elucidated by single crystal X-ray crystallography. NiCl2[(CH3S)2C═NC≡N]2 (1) features inversion-related hydrogen bonded dimers linked into chains interacting through C-H···Cl growing layers along [110] whose junction into a 3D structure is enabled by H-bonds. …”
Get full text

The S-Layer Glycome—Adding to the Sugar Coat of Bacteria by Robin Ristl, Kerstin Steiner, Kristof Zarschler, Sonja Zayni, Paul Messner, Christina Schäffer

“…As the S-layer glycome of several bacteria is unravelling, a picture of how S-layer glycoproteins are biosynthesized is evolving. X-ray crystallography experiments allowed first insights into the catalysis mechanism of selected enzymes. …”
Get full text

Insights into the Structures of DNA Damaged by Hydroxyl Radical: Crystal Structures of DNA Duplexes Containing 5-Formyluracil by Masaru Tsunoda, Takeshi Sakaue, Satoko Naito, Tomoko Sunami, Naoko Abe, Yoshihito Ueno, Akira Matsuda, Akio Takénaka

“…In order to establish the structural basis for such mutagenesis, the crystal structures of two kinds of DNA d(CGCGRATfUCGCG) with R = A/G have been determined by X-ray crystallography. The fU residues form a Watson-Crick-type pair with A and two types of pairs (wobble and reversed wobble) with G, the latter being a new type of base pair between ionized thymine base and guanine base. …”
Get full text

Proteomics and Its Current Application in Biomedical Area: Concise Review by Semira Gobena, Bemrew Admassu, Mebrie Zemene Kinde, Abebe Tesfaye Gessese

“…Various sophisticated techniques are employed in proteomics, including polyacrylamide gel electrophoresis, mass spectrometry analysis, NMR spectroscopy, protein microarray, X-ray crystallography, and Edman sequencing. These methods collectively contribute to the comprehensive understanding of proteins and their roles in health and disease. …”
Get full text

Concise Synthesis of Naphthalene-Based 14-Aza-12-Oxasteroids by Smriti Srivastava, Jun Luo, Daniel Whalen, Katherine N. Robertson, Amitabh Jha

“…A series of 14-aza-12-oxasteroids were synthesized using our developed synthetic strategy in moderate yields, and the structure of one of the final products, 12a-Methyl-11-phenyl-11,12a-dihydro-1<i>H</i>-naphtho[2,1-d]pyrrolo[2,1-b][1,3]oxazin-3(2<i>H</i>)-one, was further confirmed by single crystal X-ray crystallography.…”
Get full text

A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease by Friederike Ebner, Katja Lindner, Katharina Janek, Agathe Niewienda, Piotr H. Malecki, Manfred S. Weiss, Tara E. Sutherland, Arnd Heuser, Anja A. Kühl, Jürgen Zentek, Andreas Hofmann, Susanne Hartmann

“…The three-dimensional structure of the T. suis chitinase as determined by high-resolution X-ray crystallography revealed high similarities to mouse acidic mammalian chitinase (AMCase) but a unique ability of T. suis chitinase to form dimers. …”
Get full text

Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity by Joanna Wiecek, Dimitra Kovala-Demertzi, Zbigniew Ciunik, Joanna Wietrzyk, Maria Zervou, Mavroudis A. Demertzis

“…The structure of [Ph2(HyFoSc)Sn] was confirmed by single-crystal X-ray crystallography. The doubly deprotonated ligand is coordinated to the tin atom through the enolic-oxygen, the azomethine-nitrogen, and phenolic-oxygen, and so acts as an anionic tridentate ligand with the ONO donors. …”
Get full text

Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-... by Omoruyi G. Idemudia, Alexander P. Sadimenko, Anthony J. Afolayan, Eric C. Hosten

“…The single crystal structure of Bmpp-Sn according to X-ray crystallography showed a keto-imine tautomer type of Schiff base, having three intramolecular bonds, one short N2⋯H2⋯O3 hydrogen bond of 1.90 Å and two long C13⋯H13⋯O2 and C32⋯H32⋯O3 hydrogen bonds of 2.48 Å. …”
Get full text

Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H2dampt) by M. A. Salam, M. A. Affan, Ramkrishna Saha, Fasihuddin B. Ahmad, Norrihan Sam

“…H2dampt (1) is newly synthesized and has been structurally characterized by X-ray crystallography. Spectroscopic data suggested that H2dampt (1) is coordinated to the tin(IV) atom through the thiolate-S, azomethine-N, and phenoxide-O atoms; the coordination number of tin is five. …”
Get full text

Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives by Ayman El-Faham, Wael N. Hozzein, Mohammad A. M. Wadaan, Sherine N. Khattab, Hazem A. Ghabbour, Hoong-Kun Fun, Mohammed Rafiq Siddiqui

“…The prepared compounds were characterized by FT-IR, NMR, elemental analysis, and X-ray crystallography for derivatives 5b. The synthesized compounds were screened for antimicrobial activity against selected bacteria and fungi. …”
Get full text