Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model by Cassandra M. Flynn, Tamunotonye Omoluabi, Alyssa M. Janes, Emma J. Rodgers, Sarah E. Torraville, Brenda L. Negandhi, Timothy E. Nobel, Shyamchand Mayengbam, Qi Yuan

“…Abstract Background Alzheimer’s disease (AD) remains incurable, yet its long prodromal phase offers a crucial window for early intervention. Pretangle tau, a precursor to neurofibrillary tangles, plays a key role in early AD pathogenesis. …”
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High risk for life-threatening adverse events of fluoroquinolones in young adults: a large German population-based cohort study by Julia Wicherski, Jonas Peltner, Cornelia Becker, Katrin Schüssel, Gabriela Brückner, Andreas Schlotmann, Helmut Schröder, Winfried V. Kern, Britta Haenisch

“…Methods We conducted an administrative cohort study using the active comparator new user design with a risk window up to 365 days between January 2013 and December 2019. …”
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Enhancing safety in CT-guided lung biopsies: correlation of MinIP imaging with pneumothorax risk prediction by Michael P. Brönnimann, Leonie Manser, Bernhard Gebauer, Timo A. Auer, Dirk Schnapauff, Federico Collettini, Alexander Pöllinger, Alois Komarek, Miltiadis E. Krokidis, Johannes T. Heverhagen

“…Radiodensity measurements were performed using lung window (LW) and MinIP (10-mm slab) images. Regions of interest (ROIs) were placed at sites of the lowest density along the biopsy pathway. …”
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Risk of Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Randomized Clinical Trials: A Systematic Review and Meta-Analysis by Abdullah Reda, Alireza Hasanzadeh, Sherief Ghozy, Hossein Sanjari Moghaddam, Tanin Adl Parvar, Mohsen Motevaselian, Ramanathan Kadirvel, David F. Kallmes, Alejandro Rabinstein

“…Concomitant use of intravenous thrombolysis and the use of MT in the extended therapeutic window do not raise the risk of sICH.…”
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Realising health justice in Palestine: beyond humanitarian voices by James Smith, Sara el-Solh, Layth Hanbali, Sawsan Abdulrahim, Sali Hafez, Samer Abuzerr, Bram Wispelwey, Mads Gilbert, Mohammed Seyam, Bassam Abu Hamad, Dorotea Gucciardo, Fahd Haddad, Rasha Khoury, Amira Nimerawi, David Mills, Ghassan Abu-Sittah

“…Against the backdrop of a very limited window for what we consider morally justifiable humanitarian engagement in Gaza, we join many others who have called for a paradigm shift away from the inertia of supposed objectivity and claimed neutrality that function to perpetuate injustice. …”
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DESAIN RUMAH YANG BERKOMPROMI DENGAN SITUASI PANDEMI COVID-19 by Muhammad Zakaria Umar, Fahri Ramadhan

“…Based on the results of this study, it is concluded as follows: first, the formulation of a simple house that compromises with Covid-19 is designed by means of an open-concept house, a minimalist modern house, access to hygiene, air circulation and lighting; second, proposing the application of principles to simple house designs that compromise the covid-19 pandemic, which is realized by placing the sink on the facade; home access made effective; facades utilizing smart home technology; rooms without dividing walls and large glass window openings; the facade of the building is not ventilated; The interior and facade of the building are minimalist in design. …”
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Prevalence of Intestinal Parasites and Salmonella typhi among Food Handlers Working in Catering Establishments of Public Institutes Found in Dawuro Zone, South-Western Ethiopia by Abera Kumalo, Eyasu Gambura, Terfe Dodicho, Khawaja Shakeel Ahmed, Tamrat Balcha, Bahailu Beshir, Misrak Abraham

“…The data entered into Epi info version 3.5.1 and then exported into SPSS window version 20.0 for analysis. Logistic regressions were performed to assess the association between binary outcomes and different explanatory variables. …”
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Cognitive decline in relation to later-life high temperature exposure in a Chinese nationwide cohort by Yu-Qian Huang, Lian-Sheng Zhang, Ji-Xing Yang, Fang Wang, Ya-Qi Wang, Li-Feng Zhu, Yuan-Yuan Zhang, Bo-Ning Deng, Qian-Qian Xiang, Yun-Quan Zhang

“…This study revealed consistent evidence for heat-related declines in global cognitive performance and episodic memory across multiple exposure-window analyses, while robust associations were observed solely during prolonged exposure periods (more than 90 d) for mental status. …”
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Factors associated with non-response and nutritional status of non-responders at 6-month post-discharge: a cohort study nested in a MUAC-based nutrition programme for acutely malno... by Maguy Daures, Jérémie Hien, Cécile Cazes, Rodrigue Alitanou, Laure Saillet, Benjamin Séri, Ahmad Ag Mohamed Aly, Oumarou Maidadji, Atté Sanoussi, Aboubacar Mahamadou, Mathias Altmann, Kevin Phelan, Renaud Becquet, Susan Shepherd

“…BackgroundIn the treatment of acute malnutrition (AM), non-response is considered a treatment failure for not meeting recovery criteria within a therapeutic window of 12–16 weeks, but this category of children is misunderstood. …”
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Ocular Biometry OCR: a machine learning algorithm leveraging optical character recognition to extract intra ocular lens biometry measurements by Anish Salvi, Leo Arnal, Kevin Ly, Gabriel Ferreira, Sophia Y. Wang, Sophia Y. Wang, Curtis Langlotz, Curtis Langlotz, Vinit Mahajan, Vinit Mahajan, Chase A. Ludwig, Chase A. Ludwig

“…For each patient eye, our text extraction pipeline, referred to as Ocular Biometry OCR, involves 1) cropping the report to the biometric data, 2) extracting the text via the optical character recognition model, 3) post-processing the metrics and values into key value pairs, 4) correcting erroneous angles within the pairs, 5) computing the number of errors or missing values, and 6) selecting the window specific results with fewest errors or missing values. …”
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Design and validation of a-SiC/SiN hybrid photonic platform for integrated quantum photonics by Naresh Sharma, Zizheng Li, Bruno Lopez-Rodriguez, Joey Vrugt, Stijn van der Waal, Luozhen Li, Roald van der Kolk, Philip J Poole, Dan Dalacu, Iman Esmaeil Zadeh

“…Amorphous silicon carbide (a-SiC) has emerged as an alternative with a high refractive index (higher than SiN), an extended transparency window compared to Silicon, and a thermo-optic coefficient three times higher than that of SiN, which is crucial for tuning photonic devices on a chip. …”
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Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context by Yali Luo, Jian Gao, Xinliang Su, Helian Li, Yingcen Li, Wenhao Qi, Xuling Han, Jingxuan Han, Yiran Zhao, Alin Zhang, Yan Zheng, Feng Qian, Hongyu He

“…Immunophenotype shifts were evaluated using differential expression sliding window analysis, and random forest models were developed for sepsis diagnosis or prognosis prediction. …”
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Hepatitis B Virus in Polish Blood Donors in the Period 2005–2019—Significant Changes in Epidemiology and Demographic Characteristics of Infected Donors by Aneta Kopacz, Dorota Kubicka-Russel, Grzegorz Liszewski, Ewa Sulkowska, Anna Chrzanowska, Paulina Zwolińska, Ewa Noceń, Anna Potępa, Magdalena Łętowska, Piotr Grabarczyk, the Group of Polish Blood Transfusion Centers for Blood Borne Pathogens

“…., donors born between 1985 and 2001). The incidence of window period (WP) infections in the repeat donor group demonstrated a downward trend (R = −0.54, <i>p</i> < 0.05), and in the first-time donor group, no significant trend was recorded. …”
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Early Detection and Intervention of Preschool-Aged Children Using Android-Based Monitoring during the COVID-19 Pandemic in Central Java by Triwiji Lestari, Elisa

“…Preschool age is widely recognized as a critical phase in child development, often referred to as the golden period, the window of opportunity, and the critical period. Alarming statistics from the Indonesian Ministry of Health reveal that 16% of Indonesian toddlers, amounting to 0.4 million children, experience developmental delays, encompassing fine and gross motor skills, hearing impairments, reduced cognitive abilities, and speech delays. …”
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Research on time–frequency characteristics of electromagnetic signals from coal and rock blasting based on DBO-VMD filtering by Litao WANG, Liming QIU, Menghan WEI, Dazhao SONG, Rentao GOU, Lin LIU, Shiqiang ZHONG, Tianyi XIE

“…Rupture periods begin when information entropy falls below 4.75, instantaneous energy exceeds 1000 J, or marginal energy surpasses 100 J, based on a 50-point time window. Conversely, the conclusion of the rupture period corresponds to opposite conditions, with marginal energy responding more sensitively to rupture states than instantaneous energy. …”
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A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity by Da-yan Zhang, Zhi-hua Zhang, Wen-ting Liu, Wei-ming Zhou, Peng-fei Zhou, Juan-juan Wei, Xue-jing Dai, Xiao-li Zeng, Yu-qiong Zhou, Han-wang Li, Heng Zhang, Ao-lin Shen, Lian-sheng Cheng, Guo-dong Shen, Yi-fu He

“…Conclusion The optimal anti-MSLN×4-1BB bsAb HK013-G1 exhibited synergistic antitumour effects by inducing an ADCC effect (innate immunity) and stimulating the 4-1BB signaling pathway (adaptive immunity) upon cross-bridging with MSLN with no systemic toxicity, which may offer the promise of an improved therapeutic window relative to that of 4-1BB agonists.…”
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Cement-within-cement technique in revision reverse total shoulder arthroplasty: complications, reoperations, and revision rates at 5-year mean follow-up by Rodrigo de Marinis, MD, John W. Sperling, Jr., Erick M. Marigi, MD, Ausberto Velasquez Garcia, MD, Eric R. Wagner, MD, Joaquin Sanchez-Sotelo, MD, PhD

“…A total of 12 (17.6%) shoulders required an osteotomy (corticotomy or window) to assist with extraction of the cemented stem. …”
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Estimation of All-Sky Gridded Diurnal Near-Surface Air Temperatures at Regional Scale From FY-4B Measurements by Ronghan Xu, Xin Wang, Yonghong Hu, Lin Chen, Suling Ren, Guangzhen Cao, Di Xian, Eston Ranson Mogha

“…The multiscale geographically weighted regression model was investigated to establish the dynamic relationships between ground station observed <inline-formula><tex-math notation="LaTeX">${{T}_{air}}$</tex-math></inline-formula> and satellite LST under clear-sky conditions by employing different spatial values for each explanatory variable in localized regressions. A moving window loop based multiple linear regression was employed to establish the relationship between satellite-derived clear-sky <inline-formula><tex-math notation="LaTeX">${{T}_{air}}$</tex-math></inline-formula> and other variables to extrapolate <inline-formula><tex-math notation="LaTeX">${{T}_{air}}$</tex-math></inline-formula> in cloudy-sky pixels. …”
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Identifying the predictors of ultra early neurological improvement and its role in functional outcome after endovascular thrombectomy in acute ischemic stroke by Yuzheng Lai, Mohammad Mofatteh, José Fidel Baizabal-Carvallo, José Fidel Baizabal-Carvallo, Jianfeng He, Wenhao Wu, Daohong Wang, Wenshan Yan, Jicai Ma, Sijie Zhou, Yu Sun, Yu Sun, Yi He, Shumei Li, Hao Sun

“…In this study, we aimed to investigate the usage of NIHSS at 1-h time window -ultra-early neurological improvement (UENI)- as a surrogate marker associated with the functional outcomes of AIS patients treated with EVT.MethodsWe included 485 adults (≥18 years old) who underwent emergency EVT at four academic comprehensive stroke centers between 2020 and 2021. …”
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EVALUASI ELEMEN TEKNIS RUANG BERSAMA RUSUNAWA MAHASISWA SEBAGAI HUNIAN SEHAT DI MASA PANDEMI COVID-19 by Citra Amalia Amal, Andi Annisa Amalia, Siti Fuadillah A. Amin, Rifaldi Rifaldi

“…The data analysis technique was carried out through descriptive quantitative methods by scoring the achievement of indicators of the Healthy Home Principles in the form of dry (not damp) floors and walls, a minimum window opening area of 1/9 of the floor space, openings that can be penetrated by sunlight, the availability of natural lighting and artificial lightingin the dining room area, efforts to overcome the danger of fire in the kitchen area, waterproof walls, vents, and good lighting in the bathroom. …”
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