TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…Colony formation and Transwell assays were utilized to evaluate the effects of TWIST1 on cell proliferation, migration, and invasion. Western blotting was employed to detect proteins related to cuproptosis and apoptosis, while ubiquitination assays assessed TWIST1's regulation of HK2 ubiquitination. …”
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‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: e... by Joseph Rujumba, Carmen Roebersen, Susan Namara, Richard Ochen, Sharon Eva Ahumuza, Allen Tushabe, Mathias Akugizibwe, David Bitira, Innocent Mwesigye, Stella Kentusi, Henry Zakumumpa, Japheth Kwiringira, Merian Natukwatsa Musinguzi

“…Aidsfonds and partners in Uganda implemented an eight-year ‘Towards an AIDS Free Generation in Uganda’ (TAFU) programme in central, western and eastern, Uganda with Village Savings and Loan Associations (VSLAs) as a key component. …”
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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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Mid-term to long-term outcome and risk factors for failure of 158 hips with two-stage revision for periprosthetic hip joint infection by M. Abuelnour, C. McNamee, A. B. Rafi, W. Hohlbein, W. Hohlbein, P. Keogh, J. Cashman

“…The cumulative survival for all-cause re-revision was 88.8 % at 2 years, 80.8 % at 5 years, 74.9 % at 10 years, and 68 % at 15 and 20 years. The mean Western Ontario and McMaster Universities Arthritis Index (WOMAC) hip score significantly improved from 68.3 at the pre-operative stage to 35.9 at 2.1 (2 to 3.3) years, 35.3 at 5.3 (5 to 8.4) years, 38.3 at 11.3 (10–15) years and 43.8 at 18.7 (16.5 to 21.7) years (<span class="inline-formula"><i>p</i>&lt;0.01</span>). …”
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Helicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia by Shuwen Zheng, Yingying Wang, Chuxuan Ni, Rui Guo, Xunan Qiu, Jijun Chen, Lu Wang, Xiaohu Sun, Moye Chen, Yunen Liu, Yuan Yuan, Yuehua Gong

“…Methods Gastric epithelial cells were stimulated with H. pylori 26695, a SlyD inactivated mutant (ΔSlyD), and purified HpSlyD protein, respectively. Real-time qPCR and western blot were subsequently used to assess the expression levels of hnRNPK, TPT1, OCT1, and GIM markers. …”
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PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

“…PTEN and related protein levels were detected using RT-qPCR and Western blot. Statistical analyses were performed using the Mann-Whitney U test and Kruskal-Wallis H test. …”
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Five-year Survey of Bacterial Culture Isolates and Their Antibiogram in Pediatric Patients of Rural Tertiary Care Hospital of Central Gujarat by Krutika R Tandon, Prachi Vani, Rahul Tandon, Nirav Thakar, Swati Kamani, Amit Kumar

“…Clinical significance: It includes recent data on microorganism profiles and their antibiograms from the western part of India.…”
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Excerpts from The Freedom Fight: A Novel of Resistance and Freedom. by Pamela J. Olubunmi Smith

“… The Novel Set in 19th century traditional Yorùbáland in South Western Nigeria, Olókùn Ẹṣin is a historical tale about feudalism and enslavement, freedom and independence. …”
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Geomorphic imprint of high-mountain floods: insights from the 2022 hydrological extreme across the upper Indus River catchment in the northwestern Himalayas by A. Kashyap, K. L. Cook, M. D. Behera

“…The synoptic observations suggest that this meteorological condition involves the interaction of the Indian summer monsoon (ISM) and western-disturbance (WD) moisture fluxes. However, the geomorphic consequences of such anomalous monsoon periods, as well as their influence on long-term landscape change, are still unclear.…”
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Tectonometamorphic evolution of a subduction plate interface at the base of the Mirdita Ophiolite (Bajram Curri, northeastern Albania) by Madeline Richter, Kilian Pollok, Kujtim Onuzi, Kamil Ustaszewski

“…Abstract The Western Vardar ophiolite, a thrust sheet of oceanic crust and mantle obducted onto the Adriatic passive margin in the Late Jurassic, crops out along the entire Balkan Peninsula. …”
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RETRACTED: Mycosynthesis of Hematite (α-Fe₂O₃) Nanoparticles Using <em>Aspergillus niger</em> and Their Antimicrobial and Photocatalytic Activities by Ebrahim Saied, Salem S. Salem, Abdulaziz A. Al-Askar, Fathy M. Elkady, Amr A. Arishi, Amr H. Hashem

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Effects of coal mine dust on lung function in rats by LIU Yang, LI Meng, LU Liyuan, WANG Ru, YANG He, ZHANG Huifang

“…The relative protein expressions of PGC-1α and TFAM were detected using Western blotting. Results: There was no interaction between dust type and exposure duration on f (P>0.05), but there were interactions on FVC, PEF and Cdyn (all P<0.05). …”
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Modern contraceptive discontinuation and associated factors among adolescent girls and young women in Tanzania: An analysis of a nationally representative data by Victoria J Solomon, Shadrack E Kibona, Elevatus N Mukyanuzi, Christopher H Mbotwa

“…Factors associated with higher discontinuation rates included higher age (adjusted hazard ratio (aHR) 1.64, 95% confidence interval (CI) 1.06–2.51 for the 20–24 age group), residing in households headed by a female (aHR 1.40, 95% CI 1.05–1.85), and residing in the western zone (aHR 1.87, 95% CI 1.21–2.90). Conclusion: This study revealed a high prevalence rate of modern contraceptive discontinuation among AGYW in Tanzania. …”
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Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, T. L. Lapina, I. B. Khlynov, N. N. Dekhnich, O. D. Lopina, O. P. Alekseeva, N. V. Korochanskaya, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, G. N. Tarasova, Yu. P. Uspenskiy, D. N. Andreev, D. E. Rumyantseva

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Genesis of the term "savilaida": from collections of avant-garde poetry till Lithuanian neologism by Egidijus Jaseliūnas

“…At the meeting point of the 60s and 70s, neologism "samizdat" became more widely known in Lithuania through the circulation of the Russian samizdat and a growing number of broadcasts of the Western radio stations, which provided such material. …”
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CircHIPK2 recruits SRSF1 to increase TXNIP mRNA stability and promotes autophagy-dependent ferroptosis and apoptosis in myocardial ischemia-reperfusion injury by Zhu Zhang, Jinqi Hao, Qinghong Qiao, Junting Song, Yanqin Yu

“…Protein levels of autophagy markers (LC3II/LC3I, Beclin1, p62) and ferroptosis markers (GPX4, FTH1, ACSL4) were detected by Western blot. Cell viability and apoptosis were assessed by CCK-8 and flow cytometry. …”
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Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system by Ying Zhao, Yuke Zhong, Liuqing Wu, Jiao Yan, Weitao Lu

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Using positive deviance to enhance HIV care retention in South Africa: development of a compassion-focused program to improve the staff and patient experience by Allison J. Ober, Donald H. Skinner, Laura M. Bogart, Leletu Busakwe, Wadene Davids, Hassan Mahomed, Debbie Ling, Virginia Zweigenthal

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The book graphics of Vilnius printing houses in XVI-XVII centuries by Jolita Liškevičienė

“…Besides two inherited traditions of book illustration (the Eastern one that used two-colored printing inherited from Russian manuscripts; the Western one coming from German book decoration), a third, new and modern decoration with emblems emerged during the first period. …”
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Post-marketing safety surveillance for the recombinant zoster vaccine (Shingrix), vaccine adverse event reporting system, United States, October 2017–April 2024 by Yamin Shu, Wenxin Cheng, Xucheng He, Liu Huang, Wei Chen, Qilin Zhang

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