Preclinical evaluation of avutometinib and defactinib in high‐grade endometrioid endometrial cancer by Tobias Max Philipp Hartwich, Miranda Mansolf, Cem Demirkiran, Michelle Greenman, Stefania Bellone, Blair McNamara, Shuvro P. Nandi, Ludmil B. Alexandrov, Yang Yang‐Hartwich, Silvia Coma, Jonathan Pachter, Alessandro D. Santin

“…Mechanistic studies were performed using Western blot assays while in vivo experiments were completed in UTE10 engrafted mice treated with either vehicle, avutometinib, VS‐4718, or their combination through oral gavage. …”
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Effect of electroacupuncture on vascular remodeling in rats with cerebral ischemia by regulating irisin based on VEGF/Akt/eNOS signaling pathway by Lu Cao, Wenchao Ding, Yashuo Feng, Chong Guan, Li Liu, Hongyu Xie, Kewei Yu, Dongyan Xu, Lijuan Zhao, Xuan Sha, Xiaoman Deng, Santian Wu, Yangrui Wang, Yi Wu, Tingting Zhang, Nianhong Wang

“…Tissue distribution and expression of irisin were determined by immunofluorescence, enzyme-linked immunosorbent assay (ELISA), and Western blotting. Type III fibronectin domain protein 5-silenced adeno-associated virus (rAAV-shFNDC5) was injected into the lateral ventricle as a control. …”
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The record-breaking precipitation event of December 2022 in Portugal by T. M. Ferreira, T. M. Ferreira, R. M. Trigo, T. H. Gaspar, J. G. Pinto, A. M. Ramos

“…Over the last decade, several studies have shown the important and specific role played by atmospheric rivers (ARs) in the occurrence of EPEs in western Europe, particularly in the Iberia Peninsula. …”
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Epidemiology and Treatment Patterns of Fistulizing Crohn’s Disease in a Large, Real-World Australasian Cohort by Jack McNamara, William Wilson, Joseph L. Pipicella, Simon Ghaly, Jakob Begun, Ian C. Lawrance, Richard Gearry, Jane M. Andrews, Susan J. Connor

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In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae by Yalin Zhang, Lifang Cui, Ruibing Liu, Zili Feng, Hongjie Feng, Jinglong Zhou, Lihong Zhao, Feng Wei, Heqin Zhu

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Single-cell morphological tracking of cell states to identify small-molecule modulators of liver differentiation by Rebecca E. Graham, Runshi Zheng, Jesko Wagner, Asier Unciti-Broceta, David C. Hay, Stuart J. Forbes, Victoria L. Gadd, Neil O. Carragher

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Liver macrophage-derived exosomal miRNA-342-3p promotes liver fibrosis by inhibiting HPCAL1 in stellate cells by Wenshuai Li, Lirong Chen, Qi Zhou, Tiansheng Huang, Wanwei Zheng, Feifei Luo, Zhong Guang Luo, Jun Zhang, Jie Liu

“…The function of the target gene Hippocalcin-like protein 1 (HPCAL1) in HSCs was verified by Western blotting, qPCR, cellular immunofluorescence and co-IP in vivo and in vitro. …”
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Impact of Wildfire Smoke Events on Indoor Air Quality and Evaluation of a Low-cost Filtration Method by Nathaniel W. May, Clara Dixon, Daniel A. Jaffe

“…Indoor and outdoor hourly PM2.5 (µg m−3) measurements from the publicly available PurpleAir sensor (PAS) network were analyzed for 42 sites (26 residential, 6 school, 10 commercial) across the western US during a September 2020 period of heavy wildfire smoke influence. …”
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Can a physical activity program improve functional capacity and fatigue in people with cancer? A retrospective analysis by Aline Reinmann, Edouard Laré, Anne-Violette Bruyneel, Joseph Gligorov, Alexandre Bodmer, Thibaud Koessler

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Early-stage investigators’ experiences with an National Institutes of Health Pilot Award Program by Cyleste C. Collins, Jacqueline Dolata, Elodie Nonguierma, Mona Shediac-Rizkallah, Ashwini R. Sehgal, J. Daryl Thornton

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"In The Spirit" by A. Santoso

“…The renewed position should leave no ontological subordinationism either of the Son or the Spirit—a correction to the Eastern and the Western church formulations. In addition, the reformulation read in autothean interpretation shows how the inherent hypostasis submission fits with God’s mission in the history of salvation. …”
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A estética contemporânea: nova poética, novo olhar by Cid Ottoni Bylaardt

“…The so-called Post-Modernism in Brazil, as in most western countries, is a multiple phenomenon, full of indetermination. …”
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The March to Prussia: The Informative Value of a Peripheral Phenomenon by Werner Paravicini

“… This article not only introduces new sources that underline the importance of the march to Prussia (Preußenreisen) for the nobility of Western Europe at the time, but also highlights the challenges they faced along the way, including encounters with marauders, adverse natural conditions and captivity. …”
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Defectology and inclusion by Stine Vik, Hege Merete Somby

“…The educational system in several western countries is built upon the strategy of reducing the gap between what the “normal” child can do and the expectations of the disabled child’s competence and skills. …”
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NEW TRENDS IN MODERN MUSICOLOGY. A DISCUSSION WITH PROFESSOR NICHOLAS COOK by Bianca ŢIPLEA TEMEŞ

“…Can we shake the habit of focusing mainly on Western musical traditions? Could all these things coexist and if so, are we able to adapt our musicological tools to their requirements? …”
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Good to love or good to eat? Ethical and ideological implications of hunting, killing and the consumption of anthropomorphic animals in popular picturebooks by Kelly Hübben

“…From an early age, children are taught that animals come in different categories, some of which are good to love, and should be treated with due respect (pets) and others that are good to eat, and, at least in Western cultures, less deserving of our compassion. …”
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A CRITICAL EVALUATION OF THE UNDERSTANDING OF GOD IN J.S. MBITI’S THEOLOGY by Y Han, Jaco Beyers

“…Mbiti systematises data of the African concepts of God in a set of Western Christian doctrinal systems. He presupposes a continuity between the Christian and the African concepts of God, and overemphasises the similarities. …”
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A Single Bangle Does Not Jingle: The Twinning Imperative of Ubuntu by Nokuthula Hlabangane

“…The paper taps into the lived ethos of abantu to argue that decolonisation as a reflection of the lifeways central to the cosmic rhythm is not far off even within the patriarchal, western-centric, colonial Africa. In this way, the ubiquity of the capitalist, instrumentalist, rational reason is routinely undermined as higher ideals are lived, heralding beauty in the desert.…”
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Northward expansion of the Critically Endangered Arabian leopard in Dhofar, Oman by Hadi Al Hikmani, Khalid Al Hikmani

“…We advocate the designation of central and western areas of the Nejd as a National Nature Reserve, to protect critical habitat for the Arabian leopard and for other species in this region.…”
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Programa “Ciência sem Fronteiras”: geopolítica do conhecimento e o projeto de desenvolvimento brasileiro by Rogéria Campos de Almeida Dutra, Leonardo Francisco de Azevedo

“…Far from questioning the current Western model of development, it is based on the center-periphery model and on the supremacy of natural science as a way of integrating our country into the valued industrial and technological routes of the world system.…”
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