Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway by Maryam Darabi, Shima Byagowi, Shabnam Fayezi, Masoud Darabi, Shahab Mirshahvaladi, Mehdi Sahmani

“…Changes in mRNA and protein expression of Δ6D were then determined using real-time RT-PCR and Western blot, respectively. The expression of Δ6D (P<0.01) increased following treatment with PPARδ agonist both at mRNA and protein levels, whereas no significant change was observed after treatment with MEK/ERK1/2 pathway inhibitor. …”
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Knowledge and Awareness of Osteoporosis: A Survey of Physical Therapy Providers in Saudi Arabia by Muataz Almaddah, Fahad Alzahrani, RiziqAllah Gaowgzeh, Abdullah Alqarni, Rani Othman, Afnan Gmmash

“…The majority of participants 37% (n = 62) had more than 10 years of experience, 45% (n = 76) mainly treat orthopedic conditions, and 70% (n = 117) live in the western region. The results showed that 67.9% (n = 114) of participants had good knowledge about osteoporosis, while 19.6% (n = 33) had poor knowledge, and only 12.5% (n = 21) had excellent knowledge. …”
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Riverine microplastic discharge along the southern Black Sea coast of Türkiye by Yahya Terzi, Rafet Çağrı Öztürk, Ahmet Raif Eryaşar, İlhan Yandi, Ahmet Şahin, Fatih Yılmaz, Kenan Gedik, Sedat Gündoğdu

“…Eastern Black Sea rivers exhibited significantly higher MP levels (11.0 ± 1.57 MP m ^−3 ) compared to western rivers (5.15 ± 1.25 MP m ^−3 ). Annual MP discharge to the Black Sea was estimated at 1.49 × 10 ^11 particles. …”
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Blockchain-Assisted Generation Rescheduling in Imperfect Market Environments by Salman Tariq, Mohamed Shaaban, Hazlie Mokhlis, Nurulafiqah N. Mansor, Hasmaini Mohamad

“…In the past three decades, there has been a sweeping trend in Western and developed countries worldwide to transform the vertically integrated electricity supply chain into competitive electricity markets to diversify investment in the system and ultimately drive down operation costs. …”
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Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB by Xia Huang, Yi Zeng, Yujie Jiang, Yueqiu Qin, Weigui Luo, Shulin Xiang, Suren R. Sooranna, Liao Pinhu

“…An ARDS rat model was established using LPS with or without LBPK95A, SB203580, or SC-514 treatment. RT-PCR, western blotting, ELISA, immunofluorescence, coimmunoprecipitation, and immunohistochemical staining were used to study the expression of fractalkine and LBP and p38 MAPK and p65 NF-κB activities. …”
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GIS-based multi-criteria decision making for identifying rainwater harvesting sites by Waqed H. Hassan, Karrar Mahdi, Zahraa K. Kadhim

“…To address the severe issue of water scarcity in the western region of Iraq, this study identifies optimal potential rainwater harvesting (RWH) locations. …”
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CRP and TNF-α  Induce PAPP-A Expression in Human Peripheral Blood Mononuclear Cells by Weiping Li, Hongwei Li, Fusheng Gu

“…Analyses were conducted by ultrasensitive ELISA, western blotting, and RT-PCR following stimulation with CRP or TNF-α cytokines. …”
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Health care provider's perceived factors for the increased practice of caesarean delivery in North West Amhara referral hospitals, Ethiopia, 2022: a qualitative study by Mulat Ayele, Marta Berta, Amare Zewudie, Eyob Shitie Lake, Gizachew Yilak, Befkad Derese Tilahun, Mastewal Belayneh Aklil

“…Fifteen healthcare providers working in referral hospitals in the north-western region of Amhara were interviewed using a heterogeneous purposive sampling approach until data was saturated. …”
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Anti-Inflammatory and Antinociceptive Activities of Bufalin in Rodents by Lili Wen, Yang Huang, Xianbiao Xie, Wan Huang, Junqiang Yin, Wenqian Lin, Qiang Jia, Weian Zeng

“…We used a carrageenan-induced paw edema model to assess the anti-inflammatory activity of this compound, and Western blot analysis detected NF-κB signaling during this effect. …”
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An Ex Vivo Study on Release, Uptake, and miRNA Profile of Exosomes in Rat Lens by Junfang Zhang, Jiawei Luo, Guowei Zhang, Bai Qin, Xiumei Ren, Huaijin Guan

“…The exosomes were isolated from medium and measured in size and concentration by nanoflow cytometry (nFCM) and transmission electron microscopy (TEM) and verified with CD63 and TSG101 by Western blot. The miRNAs in exosomes released from lens epithelial cells (LECs) were sequenced. …”
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Comparing myocardial perfusion scan findings in patients with and without Covid-19 by Bahar Moasses-Ghafari, Sahar Choupani, Sajed Jahanbin, Reza Lotfi, Khaled Rahmani

“…Methods This was a cross-sectional (descriptive-analytical) study of 750 patients requiring myocardial perfusion imaging (MPI) who were referred to the nuclear medicine center of Kowsar Hospital, a teaching hospital in Sanandaj, the center of Kurdistan Province in north-western Iran. Data collection was performed during the Covid-19 pandemic, between 6 April 2020 and 21 March 2021. …”
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UGCG promotes chemoresistance and breast cancer progression via NF-κB and Wnt/β-catenin pathway activation by Li Long, Lei Wang, Yiran Liang, Fangzhou Ye, Yuhan Jin, Dan Luo, Xiaoyan Li, Yajie Wang, Yaming Li, Dianwen Han, Bing Chen, Wenjing Zhao, Lijuan Wang, Qifeng Yang

“…The role of UGCG in the malignant progression and chemoresistance of TNBC was assessed through various functional assays. Western blotting, qRT-PCR, and immunohistochemistry were employed to investigate the signaling pathways associated with UGCG in TNBC. …”
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Equilibrium study of logistics demand and logistics resource allocation in Guangdong Province by Liu Lianhua, Wu Yanling, Lyu Shiqi, Chen Zexian

“…The Pearl River Delta region holds the most abundant logistics resources, whereas many cities in northern and western Guangdong face severe shortages and are unable to meet the normal logistics demand.…”
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Protective Effect of Schisandrin on CORT-Induced PC12 Depression Cell Model by Inhibiting Cell Apoptosis In Vitro by Liu Yang, Yeqiu Wang, Lifeng An, Xinya Zhang, Jing Wang, Yi Wang, Ruyang Cheng, Chenxiang Li, Wei Ma

“…The protein expression levels of Caspase-3, Bax, and Bcl-2 in each group of cells were detected by western blot. Results. The treatment of Schisandrin significantly increased the cell viability in models of PC12. …”
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Evaluation of a pilot reintroduction program for dusky grouper (Epinephelus marginatus) juveniles in inshore marine areas off the southeast Brazilian coast by Claudia Ehlers Kerber, Caio Augusto Perazza, Eric Hallerman, Melissa Sant´Anna, Alexandre Wagner Silva Hilsdorf

“…It inhabits the eastern and southwestern Atlantic Ocean, western Indian Ocean, and Mediterranean Sea. Populations of this species have faced significant threats due to various anthropogenic activities, including environmental degradation and intensified fishing effort. …”
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Molecular characterization of feline caliciviruses isolated from several adult cats with atypical infection showing severe flu-like symptoms on a remote island in Ehime, Japan by Yuki Nishisaka, Hikaru Fujii, Fumiko Ono, Sho Kadekaru, Hiroyuki Kogiku, Yumi Une, Shione Takeguchi, Naomi Ohta, Masumi Eto, Chiharu Takeuchi, Seigou Takeuchi, Tetsuko Miki, Akihiko Tokuda, Keiko Ookawa, Yukinobu Tohya, Keita Ishijima, Akiko Okutani, Ken Maeda, Shumpei Watanabe, Shigeru Morikawa

“…We further isolated typical strains from western Japan (Osaka, Kumamoto, and Ehime) and analyzed the viral genes along with virulent strains from Aoshima. …”
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FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2 by Kongyan Zhang, Fei Zhang, Jiahe Wang

“…In vitro experiments utilized five human colon cancer cell lines and a normal colon epithelial cell line, with Western blotting and RT-PCR for protein and mRNA quantification, respectively, and lentiviral transfection to modulate FTO expression. …”
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The Mid-Twentieth Century Baby Boom and the Role of Social Influence. An Agent-Based Modelling Approach by Eli Nomes, André Grow, Jan Van Bavel

“…Around the middle of the 20th century, most Western countries experienced a surge in birth rates, called the Baby Boom. …”
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Academic and recreational reading attitudes among primary students in a rural Malaysian village by Astri Yulia, R. Malatesha Joshi, Nor Azilah Husin, Na~Thinamalar Magiswary Nadarajan, Norhayati Mohd Zin, Cheli Nadarajan

“…Positive reading attitudes are linked to better reading achievement, but research on these attitudes among ESL speakers in non-Western, rural contexts remains limited. This study explores the attitudes of 4th and 5th graders towards recreational and academic reading in a rural Malaysian village, assessing students who participated in a reading program. …”
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Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells by Yi Zhou, Yang-cheng Sun, Qiong-yan Zhang, Jing Wang, Xian-ya Zhu, Xiang-yu Su

“…Cellular uptake experiments demonstrated that miR-194 can transfer from macrophages to GC cells and exert functional effects. Western blotting and PCR analysis further confirmed that macrophage-derived miR-194 inhibits apoptosis in GC cells and enhances cisplatin resistance by downregulating PTEN. …”
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