Preclinical evaluation of avutometinib and defactinib in high‐grade endometrioid endometrial cancer by Tobias Max Philipp Hartwich, Miranda Mansolf, Cem Demirkiran, Michelle Greenman, Stefania Bellone, Blair McNamara, Shuvro P. Nandi, Ludmil B. Alexandrov, Yang Yang‐Hartwich, Silvia Coma, Jonathan Pachter, Alessandro D. Santin

“…Mechanistic studies were performed using Western blot assays while in vivo experiments were completed in UTE10 engrafted mice treated with either vehicle, avutometinib, VS‐4718, or their combination through oral gavage. …”
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Socioeconomic characteristics and relapse-free and overall survival from childhood cancer – a nationwide study based on data from the Danish Childhood Cancer Registry by Fie Stegenborg, Mathilde Bek, Charlotte Nilsson, Line H. Pedersen, Thomas Scheike, Lisa Hjalgrim, Friederike Erdmann, Kjeld Schmiegelow, Pernille Bidstrup, Line Kenborg, Jeanette Winther, Hanne Larsen, Susanne Dalton

“…Results by diagnostic groups revealed particularly low OS for children with non-central nervous system tumors whose parents were from non-Western countries (HR = 1.92, 95% CI: 1.24–2.97). …”
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Screening for schistosomiasis in a non-endemic setting: Accuracy of a rapid antibody test using finger prick blood by Margherita Ortalli, Bianca Granozzi, Michele Bacchiega, Concettina Di Lillo, Greta Roncarati, Silvia Stefania Longoni, Cristina Mazzi, Elisa Vanino, Zeno Bisoffi, Stefania Varani

“…The other tests used were microscopy on stools and urine, a serum-ICT (SCHISTOSOMA ICT IgG-IgM, LDBIO Diagnostics), an ELISA (NovaLisa Schistosoma mansoni IgG, Novatec) and a Western Blot (SCHISTO II Western Blot IgG, LDBIO Diagnostics). …”
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Quantitative impacts of climate change and human activities on grassland growth in Xinjiang, China by Hanyi Rui, Beier Luo, Ying Wang, Lin Zhu, Qinyuan Zhu

“…The main regions with increased NDVI included the western part of Changji Hui Autonomous Prefecture, the southern part of Tacheng Prefecture, and the northwestern part of the Tarim Basin; while the areas with decreased NDVI were mainly located in the western part of the study area, e.g., the Ili River basin, and the Tekes River basin. …”
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Establishment of an Experimental Procedure for Preparing Trial Serum Samples for the Specific Serodiagnosis of Toxocara canis for External Quality Assessment Schemes by Quang Huy Vu, Diep Tuan Tran, Phu Manh Sieu Tran, Van Chuong Le, Thi Diem Phuc Huynh, Quang Sang Bui

“…Among eleven samples positive by ELISA, ten of them were confirmed via Western blotting by positive reaction with 5 specific Toxocara canis bands. …”
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Effect of electroacupuncture on vascular remodeling in rats with cerebral ischemia by regulating irisin based on VEGF/Akt/eNOS signaling pathway by Lu Cao, Wenchao Ding, Yashuo Feng, Chong Guan, Li Liu, Hongyu Xie, Kewei Yu, Dongyan Xu, Lijuan Zhao, Xuan Sha, Xiaoman Deng, Santian Wu, Yangrui Wang, Yi Wu, Tingting Zhang, Nianhong Wang

“…Tissue distribution and expression of irisin were determined by immunofluorescence, enzyme-linked immunosorbent assay (ELISA), and Western blotting. Type III fibronectin domain protein 5-silenced adeno-associated virus (rAAV-shFNDC5) was injected into the lateral ventricle as a control. …”
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The record-breaking precipitation event of December 2022 in Portugal by T. M. Ferreira, T. M. Ferreira, R. M. Trigo, T. H. Gaspar, J. G. Pinto, A. M. Ramos

“…Over the last decade, several studies have shown the important and specific role played by atmospheric rivers (ARs) in the occurrence of EPEs in western Europe, particularly in the Iberia Peninsula. …”
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UPLC-MS metabolite profiling and antioxidant activity of Sanghuangporus sanghuang extract by Weike Wang, Na Lu, Cheng Jiang, Guanping Chen

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Single-cell morphological tracking of cell states to identify small-molecule modulators of liver differentiation by Rebecca E. Graham, Runshi Zheng, Jesko Wagner, Asier Unciti-Broceta, David C. Hay, Stuart J. Forbes, Victoria L. Gadd, Neil O. Carragher

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“If the End Justifies the Means, Then This Is Permissible…”: Academic Deviations of Russian Postgraduate Students in Socio-Humanitarian Areas by M. A. Kashina, V. A. Vasilyeva, S. Tkach

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Phenotypic insights into genetic risk factors for immune-related adverse events in cancer immunotherapy by Haochuan Ma, Dili Song, Haibo Zhang, Taidong Li, Xing Jin

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Serum interleukin-6, interleukin-8, and interleukin-1 receptor antagonist levels in South Indian fibromyalgia patients and its correlation with disease severity by Sandeep Surendran, C B Mithun, Vishnu S Chandran, Suma Balan, Arun Tiwari

“…Different studies, mainly done in the Western population, have shown dysregulated cytokines in fibromyalgia patients. …”
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Liver macrophage-derived exosomal miRNA-342-3p promotes liver fibrosis by inhibiting HPCAL1 in stellate cells by Wenshuai Li, Lirong Chen, Qi Zhou, Tiansheng Huang, Wanwei Zheng, Feifei Luo, Zhong Guang Luo, Jun Zhang, Jie Liu

“…The function of the target gene Hippocalcin-like protein 1 (HPCAL1) in HSCs was verified by Western blotting, qPCR, cellular immunofluorescence and co-IP in vivo and in vitro. …”
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Epidemiological Characteristics and Trends in the Incidence of Newly Diagnosed Pulmonary Tuberculosis in China from 2016 to 2022 by Caihong Xu, Yaxin Wen, Dongmei Hu, Yuhong Li, Yanlin Zhao

“…The PTB notification rate showed the following spatial distribution: western region > central region > eastern region. …”
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Diagenetic Heterogeneity of Deep Sandstones and Its Relationship to Oil Emplacement: A Case Study from the Middle Jurassic Toutunhe Formation in the Fukang Sag, Central Junggar Bas... by Binfeng Cao, Xiaorong Luo, Likuan Zhang, Fenggui Sui, Huixi Lin, Yuhong Lei

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Betaine Treatment Attenuates Chronic Ethanol-Induced Hepatic Steatosis and Alterations to the Mitochondrial Respiratory Chain Proteome by Kusum K. Kharbanda, Sandra L. Todero, Adrienne L. King, Natalia A. Osna, Benita L. McVicker, Dean J. Tuma, James L. Wisecarver, Shannon M. Bailey

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Impact of Wildfire Smoke Events on Indoor Air Quality and Evaluation of a Low-cost Filtration Method by Nathaniel W. May, Clara Dixon, Daniel A. Jaffe

“…Indoor and outdoor hourly PM2.5 (µg m−3) measurements from the publicly available PurpleAir sensor (PAS) network were analyzed for 42 sites (26 residential, 6 school, 10 commercial) across the western US during a September 2020 period of heavy wildfire smoke influence. …”
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Dynamics‐Oriented Underwater Mechanoreception Interface for Simultaneous Flow and Contact Perception by Hua Zhong, Yaxi Wang, Jiahao Xu, Yu Cheng, Sicong Liu, Jia Pan, Wenping Wang, Zheng Wang

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Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway by Shi F, Wei Y, Huang Y, Yao D

“…The expression of Wnt3a and β-catenin were investigated using quantitative real-time PCR and Western blot.Results: ATF5 was overexpressed in cervical cancer, and upregulation of ATF5 expression was associated with a poor prognosis. …”
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Assessment of crack growth development in main pipeline on the basis of elastoplastic model by К. А. Vansovich, I. P. Aistov, А. А. Nakhlestkin, D. S. Beseliya

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