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5521
Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells
Published 2024-01-01“…To assess how this compound affects cell migration and invasion, the Boyden chamber assay was employed. Furthermore, Western blot analysis was utilized to explore the underlying molecular mechanisms. …”
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5522
Acceptability and feasibility of pre-exposure prophylaxis for bacterial STIs: a systematic review.
Published 2025-01-01“…Similarly, the perspectives of populations beyond GBMSM have been omitted, and there is little understanding of the impact of their differing socio-cultural contexts around sex-related behaviour and Western pharmaceutical healthcare interventions on their acceptance and uptake.…”
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5523
Electroacupuncture Therapy Effectively Protects the Rat Brain after Intracerebral Hemorrhage
Published 2024-01-01“…The expression levels of the CD68, GALC, Arg-1, iNOS, NR2A, Glu2R, AQP4, MAP2, GFAP, AQP9, Bcl-2, Bax, and Glu proteins around the hematoma were detected via immunohistochemistry staining. Western blot was used to analyze the levels of the AQP4, AQP9, Bax, Bcl-2, iNOS, and Arg-1 proteins. …”
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5524
Effects of Polygonatum sibiricum Polysaccharides (PSP) on Human Esophageal Squamous Cell Carcinoma (ESCC) via NF-κB Signaling Pathway
Published 2019-01-01“…The proliferation rate of Eca109 cells in each group was measured with the CCK8 assay, and the apoptosis rate in each group was analyzed by flow cytometry; the in vitro scratch assay was used to determine the migration ability of Eca109 cells after PSP treatment; the expression levels of IL-1, IL-6, IL-10, TNF-α, and TGF-β were measured by RT-PCR, and the expression levels of TLR4 and proteins that are related to NF-κB signaling pathways were determined by Western blot. Results. PSP significantly inhibited the proliferation of Eca109 cells (p<0.05) on a time- and dose-dependent manner; the apoptosis rates of Eca109 cells in experimental groups were significantly increased after 48 h of culture (p<0.05); PSP significantly reduced the migration and invasion ability of Eca109 cells (p<0.05); RT-PCR results showed that the expression of IL-10 in Eca109 cells increased significantly after treatment with PSP (p<0.05), while the expression of IL-1, IL-6, TNF-α, and TGF-β decreased significantly (p<0.05). …”
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5525
Directions for the implementation of foreign experience in operative and investigative counteraction to intentional murders by criminal police units (on the example of Canada and t...
Published 2022-09-01“…Modern criminology distinguishes Anglo-American, Western European, East Asian, socialist, Muslim and mixed criminological systems. …”
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Connexin 37 Regulates the Kv1.3 Pathway and Promotes the Development of Atherosclerosis
Published 2022-01-01“…The protein and mRNA expression levels of Cx37 and Kv1.3 were detected by reverse transcription-PCR (RT-PCR), Western blot, and immunofluorescence technique. Oil red O staining was used to observe plaque area. …”
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5529
DC/TMD Examiner Protocol: Longitudinal Evaluation on Interexaminer Reliability
Published 2018-01-01Get full text
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5530
The interphase period “germination–heading” of 8x and 6x triticale with different dominant Vrn genes
Published 2021-10-01“…The results of studying the interphase period “germination–heading” of spring octaploid and hexaploid forms of triticale created for use in research and breeding programs under the conditions of forest-steppe of Western Siberia are given in this article. The interphase period of the primary forms 8xVrnA1, 8xVrnB1 and 8xVrnD1 obtained by artificial doubling of the chromosome number of the wheat-rye hybrids made by pollination of three lines of the soft wheat ‘Triple Dirk’ – donors of different dominant Vrn-1 genes – by a winter rye variety ‘Korotkostebel’naya 69’ was determined under the field conditions in the nursery of octaploid (8x) triticale. …”
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5531
Advancing Wildlife Protection: Mask R-CNN for Rail Track Identification and Unwanted Object Detection
Published 2023-01-01Get full text
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5533
Role of the Arab League in Structuring the Arab Regional Space
Published 2020-11-01“…The LAS in its documents built a common Arab narrative, having two underpinnings: the recognition of the Palestinian Arab people as a victim of the Western powers and Zionists, as well as foreign policy of Israel.The article traces the relationship between the activities of the Arab League and the changes that have occurred in the regional and international environment. …”
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5534
Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease
Published 2020-01-01“…Subsequently, body weight changes, liver weight, serum liver function and lipid profiles, and liver pathology were examined, and the relative levels of fatty acid synthesis and β-oxidation gene expression were evaluated by western blot. Serum AST, ALT, and TG levels in the HFD control mice were significantly higher than those of normal mice. …”
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5535
Polymorphism of the LCT gene regulatory region in Turkicspeaking populations of the Altay-Sayan region (southern Siberia)
Published 2017-02-01“…The expansion of the “European” allele LCT-13910T to the gene pool of the populations in southern Siberia could be related to migration waves of ancient herders form western Eurasia during the Bronze Age (in III – II millennium BC). …”
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5536
Pre-Operative Scapular Rehabilitation for Arthroscopic Repair of Traumatic Rotator Cuff Tear: Results of a Randomized Clinical Trial
Published 2021-02-01“…Compared to CG, the EG presented a significantly higher SF-12 physical component after three months (48.47 vs. 40.33, p < 0.05), and a significantly lower Western Ontario Rotator Cuff Index (WORC) total after one year (85.00 vs. 1130.00, p < 0.05)…”
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circHUWE1 Exerts an Oncogenic Role in Inducing DDP-Resistant NSCLC Progression Depending on the Regulation of miR-34a-5p/TNFAIP8
Published 2021-01-01“…The quantitative real-time polymerase chain reaction (RT-qPCR) and western blot analyses were used for examining circHUWE1, microRNA-34a-5p (miR-34a-5p), and tumor necrosis factor alpha-induced protein 8 (TNFAIP8). …”
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Qingfei Tongluo Mixture Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis through mTOR-Dependent Autophagy in Rats
Published 2024-01-01“…Immunohistochemistry and Western blotting were performed to observe changes in proteins related to pulmonary fibrosis (α-smooth muscle actin (α-SMA) and matrix metalloproteinase 12 (MMP12)) and autophagy (P62 and mechanistic target of rapamycin (mTOR)). …”
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