Grem1 inhibits osteogenic differentiation of MBMSCs in OVX rats through BMP/Smad1/5 signaling pathway by Shan-shan Yang, Min LinHu, Xiao-hua Hu, Si-si Jiang, Wen-yue Hu, Xiao-hong Yang

“…Materials and methods: A postmenopausal osteoporosis (POP) rat model was constructed via bilateral ovariectomy. Techniques such as Western Blot (WB) and Real-Time Quantitative PCR (RT-qPCR) were employed to determine changes in Grem1 expression in MBMSCs of postmenopausal rats and its effect on osteogenic differentiation. …”
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Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice by Dong Han, Jue Wang, Lulu Wen, Miao Sun, Hang Liu, Yan Gao

“…Nuclear factor κB (NF-κB) and peroxisome proliferator-activated receptor γ (PPARγ) levels were detected using Western blot. Results. At 24 and 72 h after MCAO, RIPC drastically attenuated infarct size and ameliorated the neurological deficits of mice and facilitated transmigration of Ly6Chi monocytes to the brain postischemia reperfusion. …”
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Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice by Lijun Zou, Fen Lin, Jinying Wen, Jinyu Huang, Yue Tan, Hui Huang, Gonghua Hu

“…We administered HQ at doses of 0, 12.5, 25.0, and 50.0 mg/kg over a period of 13 weeks, followed by biochemical analyses, RNA sequencing, and Western blotting to elucidate the underlying mechanisms. …”
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Investigation and analysis of cycles and spatial correlation model of Iranian monthly rainfalls by rahmatollah shojaei moghadam, Mostafa karampoor, behroz nasiri, naser tahmasebipour

“…The analysis of the auto-correlation model of rainfall showed that the high spatial auto-correlation model in winter was consistent with the western, southwestern and coastal of the Caspian Sea and covered about 14% of the country's. …”
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Visual Imagery in Modern Mind-Body Practices: Biophotonic Information Transfer through Water-Mediated Neural Resonance by Valeriy Babelyuk, Igor Popovych, Olga Smoleńska, Anna Michalska, Radosław Muszkieta, Magdalena Hagner-Derengowska, Yuriy Dobrovolsky, Galyna Dubkova, Tetyana Korolyshyn, Walery Zukow

“…These findings bridge traditional Eastern practices with Western biophysical measurements, opening new avenues for understanding mind-body interactions.     …”
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Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a... by Kagbadouno, Moise S, Séré, Modou, Ségard, Adeline, Camara, Abdoulaye Dansy, Camara, Mamadou, Bucheton, Bruno, Bart, Jean-Mathieu, Courtin, Fabrice, De Meeûs, Thierry, Ravel, Sophie

“…In Guinea, the mangrove ecosystem contains the main HAT foci of Western Africa. There, the cyclical vector is Glossina palpalis gambiensis. …”
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Projection of glacier changes over the Laohugou Glacier No. 12, Northeast Tibetan Plateau, China from 2020 to 2100 by Mengyuan Liu, Baojuan Huai, Lei Wang, Yuzhe Wang, Hongmin An, Jizu Chen, Wentao Du, Xiang Qin, Weijun Sun

“…In this study, Laohugou Glacier No. 12 (LHG12), in the western QMs, was selected as a study area. Based on the Coupled Model Intercomparison Project (CMIP6) models, the degree-day and glacier retreat models were used to predict the glacier changes under three scenarios for 2020–2100. …”
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The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity by Yujia Li, Max Xuezhong Ma, Bo Qin, Liang-Tzung Lin, Christopher D. Richardson, Jordan Feld, Ian D. McGilvray, Limin Chen

“…The IFN signaling pathway was assessed via STAT1 phosphorylation (western blot) and downstream ISG expression (real-time PCR). …”
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Challenges faced by women oncologists in Africa: a mixed methods study by Doreen Ramogola-Masire, Reshma Jagsi, Matthew Jalink, Verna Vanderpuye, Nwamaka Lasebikan, Miriam Mutebi, Nazik Hammad, Susan Msadabwe, Laura Carson, Dorothy Chilambe Lombe, Zainab Doleeb, Haimanot Kasahun Alemu, Nesrine Chraiet, Naa Adorkor Aryeetey, Zainab Mohamed, Nazima Jaffer Dharsee, Sitna Mwanzi, Khadija Warfa, Emmanuella Nwachukwu, Edom Seife Woldetsadik, Hirondina Vaz Borges Spencer

“…Objective Recent studies have identified challenges facing women oncologists in Western contexts. However, similar studies in Africa have yet to be conducted. …”
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Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway by Chuan Lv, Can Wu, Yue-hong Zhou, Ying Shao, Guan Wang, Qiu-yue Wang

“…The effect of LA on high glucose-induced cell proliferation, fibronectin (FN), and collagen type I (collagen-I) expression and its mechanisms were examined in cultured rat mesangial cells by methylthiazol tetrazolium (MTT) assay, flow cytometry, ELISA assay, and western blot, respectively. LA at a relatively low concentration (0.25 mmol/L) acted as a growth factor in rat mesangial cells, promoted entry of cell cycle into S phase, extracellular matrix formation, and phosphorylated AKT, mTOR, p70S6K, and 4E-BP1. …”
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Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma by Gorkem Odabas, Metin Cetin, Serdar Turhal, Huseyin Baloglu, A. Emre Sayan, Tamer Yagci

“…Transcript and protein levels of Plexin C1 in HCC cell lines were determined by RT-qPCR and Western blotting, respectively. In vivo evaluation of Plexin C1 expression in HCC tissues was accomplished by immunohistochemistry studies in tissue microarrays. …”
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The Epidemiology of Migraine Headache in Arab Countries: A Systematic Review by Ashraf El-Metwally, Paivi Toivola, Khalid AlAhmary, Salwa Bahkali, Ali AlKhathaami, Shatha A. Al Ammar, Ibrahim M. Altamimi, Saleh M. Alosaimi, Munazza Jawed, Sami Almustanyir

“…The prevalence and risk factors of migraine headache in Arab countries are comparable to reports from western countries. Longitudinal studies are still needed to investigate the prognosis and predictors of chronicity in the arab countries.…”
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Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway by Liang Xiao, Zhang Jie, Luo Ya

“…The HCN1-OE group exhibited increased apoptosis, elevated ROS, and decreased survival. Western blot (WB) analysis revealed increased levels of p65, p-IκB, IKKβ, NLRP3, Beclin-1, and LC3 II/I proteins in the HCN1-OE group. …”
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Is Rhodamine 123 an Appropriate Fluorescent Probe to Assess P-Glycoprotein Mediated Multidrug Resistance in Vinblastine-Resistant CHO Cells? by Jordi Pétriz, José Enrique O’Connor, Mercè Carmona, Joan García‐López

“…These parental CHO‐K1 cells had a very low reactivity against the C219 Mab, as confirmed by Western blot analysis. Both vinblastine and verapamil inhibited Rho123 efflux in CHO‐K1 cells, but had no effect on CHOVBR cultures. …”
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5-Methoxytryptophan Alleviates Dextran Sulfate Sodium-Induced Colitis by Inhibiting the Intestinal Epithelial Damage and Inflammatory Response by Yanling Wang, Jun Li, Qinyuan Yang, Zhenhang Zhu, Fang Cheng, Xiangyan Ai, Yang Liu, Dongbao Zhao, Futao Zhao, Peng Cheng

“…Furthermore, the macrophage infiltration and release of inflammatory factors through western blot (WB) and hematoxylin–eosin staining analyses were examined. …”
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Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways by Antonia Cianciulli, Rosaria Salvatore, Chiara Porro, Teresa Trotta, Maria Antonietta Panaro

“…Inducible NO synthase (iNOS), nuclear transcription factor-kappa B (NF-κB) p65, MAPKs protein, and suppressors of cytokine signaling (SOCS)1 and SOCS3 were analyzed by western blotting. TNF-α and IL-1β, as well as iNOS dependent NO production, resulted significantly inhibited by folic acid pretreatment in LPS-activated BV-2 cells. …”
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Stability of parenteral drugs in hospital circuit by Sarah BOUAMEUR, Aicha BRAHMI, Mimouna BOUNAB, Aicha KHELLIFI

“…Materials and methods- Firstly, a cross-sectional descriptive study was carried out over three months in three hospital in western of Algeria. Bad conditions of storage, preparation and administration as well as instabilities have been identified on parenteral drugs with long expiry dates. …”
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HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway by Min Zhao, Yao-Yao Bian, Li-Li Yang, Yan-Qi Chen, Ya-Jie Wang, Yan-Ting Ma, Yu-Qiong Pei, Wen-Lin Li, Li Zeng

“…Histopathology, flow cytometry, ELISA, real-time PCR, and Western blotting were used to further detect the related protein, M1/M2 polarization tendency, and PPAR-γ nuclear translocation. …”
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Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells by Alessio Cimmino, Magda Gioia, Maria Elisabetta Clementi, Isabella Faraoni, Stefano Marini, Chiara Ciaccio

“…Analysis of the oxidative stress regulators SIRT1 and Nrf2 at the gene and protein levels using real-time PCR and Western blot indicates an early oxidative response to PD treatment. …”
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Fault Diagnosis of Signal Equipment on the Lanzhou-Xinjiang High-Speed Railway Using Machine Learning for Natural Language Processing by Lei Shi, Yulin Zhu, Youpeng Zhang, Zhongji Su

“…The Lanzhou-Xinjiang (Lan-Xin) high-speed railway is one of the principal sections of the railway network in western China, and signal equipment is of great importance in ensuring the safe and efficient operation of the high-speed railway. …”
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