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4501
The Mid-Twentieth Century Baby Boom and the Role of Social Influence. An Agent-Based Modelling Approach
Published 2019-04-01“…Around the middle of the 20th century, most Western countries experienced a surge in birth rates, called the Baby Boom. …”
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4502
Academic and recreational reading attitudes among primary students in a rural Malaysian village
Published 2024-06-01“…Positive reading attitudes are linked to better reading achievement, but research on these attitudes among ESL speakers in non-Western, rural contexts remains limited. This study explores the attitudes of 4th and 5th graders towards recreational and academic reading in a rural Malaysian village, assessing students who participated in a reading program. …”
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4503
Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells
Published 2025-02-01“…Cellular uptake experiments demonstrated that miR-194 can transfer from macrophages to GC cells and exert functional effects. Western blotting and PCR analysis further confirmed that macrophage-derived miR-194 inhibits apoptosis in GC cells and enhances cisplatin resistance by downregulating PTEN. …”
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4504
Analysis of the Influence of the Distribution and Development of Soil Caves on the Stability of High-Voltage Transmission Tower Foundations
Published 2022-01-01“…In this paper, combined with an engineering case in western Hubei, first, FLAC3D finite element software is used to analyze the influence of a single underground soil cave during continuous development and expansion on 500 kV transmission towers. …”
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4505
Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation
Published 2024-10-01“…The effects of MSCs and their combination with MPFF (diosmin-hesperidin) were evaluated through histological examinations, western blot analysis, and gelatin zymography. Results Characterization confirmed the MSCs’ plastic adherence, osteogenic differentiation potential, and immunophenotype (positive for CD90 and CD29, negative for CD45 and CD31). …”
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4506
Healthy enough to work up to age 67 and beyond? A longitudinal population-based study on time trends in working life expectancy free of cardiovascular diseases based on German heal...
Published 2024-04-01“…Background Due to the rising life expectancy in Western countries, the discussion about the increase in the retirement age is becoming more important. …”
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4507
Inhibition of Androgen Receptor Expression with Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells
Published 2013-01-01“…We compared expressions of AR, heat shock protein 27 (HSP27), clusterin (CLU), glucose-related protein 78 (GRP78), and cellular FLICE-like inhibitory protein (c-FLIP) and their genes between es-LNCaP (less than 33 times subcultured, L-33), ls-LNCaP (over 81 times subcultured, H-81), and si-LNCaP (AR siRNA transfected ls-LNCaP) by Western blotting and RT-PCR. Results. The expressions of AR, HSP27, CLU, GRP78, and c-FLIP were increased in ls-LNCaP compared with es-LNCaP (AR, 157%; HSP27, 132%; CLU, 146%; GRP78, 138%; c-FLIP, 152%). …”
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4508
Repellent Activities of Essential Oils of Some Plants Used Traditionally to Control the Brown Ear Tick, Rhipicephalus appendiculatus
Published 2014-01-01“…Essential oils of eight plants, selected after an ethnobotanical survey conducted in Bukusu community in Bungoma County, western Kenya (Tagetes minuta, Tithonia diversifolia, Juniperus procera, Solanecio mannii, Senna didymobotrya, Lantana camara, Securidaca longepedunculata, and Hoslundia opposita), were initially screened (at two doses) for their repellence against brown ear tick, Rhipicephalus appendiculatus, using a dual-choice climbing assay. …”
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4509
Metformin Regulating miR-34a Pathway to Inhibit Egr1 in Rat Mesangial Cells Cultured with High Glucose
Published 2018-01-01“…Quantitative real-time PCR was used to assay the transcription levels of Egr1 mRNA and miR-34a. Western blot was used to test the protein. And ELISA was used to measure inflammatory factors. …”
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4510
Activation of Opioid Receptors Attenuates Ischemia/Reperfusion Injury in Skeletal Muscle Induced by Tourniquet Placement
Published 2021-01-01“…Expression levels of TLR4, NF-κB, SIRT1, and PGC-1α in the skeletal muscles were detected by western blot. Blood TNF-α levels, gastrocnemius muscle contractile force, and ATP concentration were examined. …”
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4511
METTL3-dependent DLG2 inhibits the malignant progression of cervical cancer by inactivating the Hippo/YAP signaling
Published 2025-01-01“…Methods Quantitative reverse transcription polymerase chain reaction and western blotting assays were employed to detect RNA and protein expression, respectively. …”
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4512
Ophiostomatoid fungi associated with mites phoretic on bark beetles in Qinghai, China
Published 2020-07-01“…We studied the mites and fungi from galleries of four spruce-infesting bark beetle species in the high altitude forests of Qinghai province, western China. Mites were identified based on morphological characteristics, and fungi based on DNA sequences of four gene regions. …”
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4513
A dataset on environmental DNA, bacterio-, phyto- and zooplankton from an emerging periglacial lagoon in Svalbard, ArcticMendeley DataMendeley Data
Published 2025-02-01“…The data presented here were collected from an emerging lagoon in the western region of Spitsbergen, Svalbard, situated between the retreating Eidembreen Glacier and Eidembukta Bay in 2022–2023. …”
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4514
Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways
Published 2024-01-01“…In addition, Toll-like receptor 4 (TLR4) receptor inhibitors were able to block the production of NO and TNF-α by SCP3-stimulated macrophages. Based on Western blot analysis and validation using specific inhibitors against MAPK and NF-κB signaling pathways, the results demonstrated that SCP3 induced macrophages activation and enhanced TNF-α and NO production via TLR4-mediated MAPK and NF-κB pathways. …”
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4515
Spatial variation of land use carbon budget and zoning for carbon compensation in the Huai River Eco-economic Belt, China
Published 2025-01-01“…Results indicate that (1) Carbon emissions in the Huai River Eco-economic Belt are generally showing a downward trend, and carbon absorption rises modestly. (2) Carbon emissions exhibit a spatial distribution of higher in the western, northern and eastern regions and lower in the center zone, with large differences in carbon absorption among cities in the same year. (3) Carbon compensation types in the Huai River Eco-economic belt include 7 payment zones, 5 balanced zones and 14 compensated zones, which can be finally classified into 5 categories of carbon compensation space optimization areas by combining with the Normalized Revealed Comparative Advantage Index and model for zoning of carbon compensation. …”
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4516
Command, Control and Co-Creation: Drivers and Barriers Faced by Professionals Co-Creating in the Slovenian Public Sector
Published 2022-05-01“…Secondly, by being placed in the Slovenian administrative context, the paper complements and enriches the debate on co-creation shaped predominantly by the experience of Northern and Western Europe. Purpose: By focusing on the Slovenian public sector, as a traditionally hierarchical administrative context, the paper aims to identify factors that stimulate professionals to implement co-creation in their everyday work, as well as factors that impede their decision and behaviour in this direction. …”
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4517
Wild pea (<i>Pisum sativum</i>Pisum sativum L. subsp. <i>elatius</i> (Bieb.) Aschers. et Graebn. s.l.) at the periphery of its range: Zagros Mountains
Published 2020-03-01“…Scarce information available on wild pea occurrence in Iran suggests their existence in the south-western principal slope of Zagros Mts and southern principal slopes of Elborz and Kopet Dagh Mts. …”
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4518
Filling the Atlantic coastal tree-ring reconstruction gap: A 195-year record of growing season discharge of the Sainte-Anne River, Gaspésie, Québec, Canada
Published 2025-04-01“…While energy-limited tree-ring chronologies are well-known in western North America, they are poorly known in eastern North America. …”
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4519
Changes in the Order of Family Life Events in 20th-Century Europe: A Cross-Regional Perspective
Published 2017-03-01“…In Eastern Europe where family event sequences have become less standardized and where a particular sequence characterized by the reversal of the traditional order between leaving home and family formation has been observed, the hypothesized transition is still in its very beginning. In Western Europe the transition is clearly on its way, but no re-standardization towards a new standard can be observed as for now. …”
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4520
Tangduqing Granules Attenuate Insulin Resistance and Abnormal Lipid Metabolism through the Coordinated Regulation of PPARγ and DGAT2 in Type 2 Diabetic Rats
Published 2019-01-01“…After oral administration of TDQ for 5 weeks, the effects on glucose and lipid metabolism and the underlying mechanism were evaluated by biochemical, histological, RT-PCR, and western blotting methods. The results showed that TDQ decreased fasting blood glucose, ameliorated glucose tolerance, and improved IR. …”
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