Vitamin D Status in Central Europe by Pawel Pludowski, William B. Grant, Harjit Pal Bhattoa, Milan Bayer, Vladyslav Povoroznyuk, Ema Rudenka, Heorhi Ramanau, Szabolcs Varbiro, Alena Rudenka, Elzbieta Karczmarewicz, Roman Lorenc, Justyna Czech-Kowalska, Jerzy Konstantynowicz

“…Concentrations of 25(OH)D in CE appeared lower than 30 ng/mL, and the magnitude of hypovitaminosis D was similar to that reported in Western Europe. While most of the studies reviewed were cross-sectional studies, a longitudinal study was also included to obtain information on seasonal variability. …”
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Bridging the Gap: Misaligned Perceptions of Urban Agriculture and Health Between Planning and Design Experts and Urban Farmers in Greater Lomé, Togo by Akuto Akpedze Konou, Kossiwa Zinsou-Klassou, Pablo Txomin Harpo De Roulet, Armel Firmin Kemajou Mbianda, Jérôme Chenal

“…In particular, the amount of land devoted to UA in these cities exceeds that used in Western countries, presenting challenges in areas such as land tenure. …”
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Qufeng epimedium decoction alleviates rheumatoid arthritis through CYLD-antagonized NF-kB activation by deubiquitinating Sirt1 by Zhiming Wu, Peng Zhang, Wenyan Huang, Yifen Zhou, Zhengliu Cao, Chunhong Wu

“…Methods: The RA animal model was established to investigate the anti-RA effect and regulatory effect on fibroblast-like synoviocytes (FLS) pyroptosis, qRT-PCR, Western blot, flow cytometry, histology staining, and ELISA were utilized to confirm the gene and protein expressions. …”
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Electroacupuncture Mitigates Hippocampal Cognitive Impairments by Reducing BACE1 Deposition and Activating PKA in APP/PS1 Double Transgenic Mice by Yinshan Tang, Shujun Shao, Yu Guo, You Zhou, Jin Cao, Anping Xu, Jihong Wu, Zhigang Li, Dulian Xiang

“…Immunofluorescence, immunohistochemistry, and western blot were employed to assess the distribution patterns and expression levels of BACE1, APP, and p-PKA, respectively. …”
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Characteristics of salt dust aerosols and their transport implications in the Aral Sea by Jie Liu, Jianli Ding, Bohua Liu, Shu Wu, Zhijuan Han

“…From 2013 to 2018, the salt dust sources originated largely on the western side of the North Aral Sea. The spatial autocorrelation of salt dust aerosols was high and characterized by significant agglomeration, with significant changes in cold spot and hotspot regions. …”
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Second-generation BRAF inhibitor Encorafenib resistance is regulated by NCOA4-mediated iron trafficking in the drug-resistant malignant melanoma cells by Ceyda Colakoglu Bergel, Isil Ezgi Eryilmaz, Gulsah Cecener, Unal Egeli

“…After establishing Encorafenib-resistant A375-MM cells, resistant-related mechanisms were investigated using WST-1, Annexin V, cell cycle, morphological analysis, live-cell, Western blot, RNA-Seq, transmission electron microscopy-(TEM), oxidative stress and iron colorimetric assay. …”
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Tourism Development of Cultural Heritage Resources Through Conservation Concepts: A Case Study of Ningxia, China by Shengrui Zhang, Tianyi Hu, Tongyan Zhang, Hongrun Ju, Yingjie Wang

“…The findings reveal: (1) Religious and Ceremonial Sites: Ningxia boasts the highest number of religious and ceremonial sites, totaling 1741. (2) Geographical Distribution: Resources are distributed in a multicore pattern, concentrated in Longde and Zhongning Counties, while the central and western areas are less rich. (3) Regional Concentration: The eastern region shows a high concentration of resources, contrasting with the low concentration in the north. (4) Influencing Factors: Social factors like GDP per capita, urbanization, and population density significantly affect this spatial pattern, although natural factors like altitude are also important. …”
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Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway by Yajuan Lin, Yunpeng Xie, Zhujing Hao, Hailian Bi, Yang Liu, Xiaolei Yang, Yunlong Xia

“…Cell phenotype was determined by cytometry and Western blot. Nuclear translocation of Nrf2 was determined by immunofluorescence. …”
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<i>Bacillus thuringiensis</i> Cry1A Insecticidal Toxins and Their Digests Do Not Stimulate Histamine Release from Cultured Rat Mast Cells by Hisashi Ohto, Mayumi Ohno, Miho Suganuma-Katagiri, Takashi Hara, Yoko Egawa, Kazuya Tomimoto, Kosuke Haginoya, Hidetaka Hori, Yuzuri Iwamoto, Tohru Hayakawa

“…In this study, three lepidopteran-specific Bt toxins, Cry1Aa, Cy1Ab, and Cry1Ac, were treated with simulated digestive fluids under various conditions. Western blotting using antiserum raised against individual segments (α-helices of domain I and β-sheets of domains II and III) of Cry1Aa showed that digestion produces a variety of polypeptides. …”
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The Interactive Relationship between Pain, Psychosis, and Agitation in People with Dementia: Results from a Cluster-Randomised Clinical Trial by Torstein F. Habiger, Elisabeth Flo, Wilco P. Achterberg, Bettina S. Husebo

“…Secondary analyses are from a cluster-randomised controlled trial including 352 patients with advanced dementia and agitation from 18 nursing homes in Western Norway. The intervention group received pain treatment according to SPTP. …”
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METTL14 modulates the progression and ferroptosis of colitis by regulating the stability of m6A-modified GPX4 by Yuhua Chen, Weicong Fan, Ying Lyu, Jingsheng Liao, Ying Zhou

“…The expression levels of METTL14 were analyzed via qRT-PCR and western blot. In vitro functional experiments evaluated the effects of METTL14 overexpression on the viability of DSS-induced NCM460 cells and ferroptosis markers. …”
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Future changes in compound explosive cyclones and atmospheric rivers in the North Atlantic by F. Lopez-Marti, F. Lopez-Marti, M. Ginesta, D. Faranda, A. Rutgersson, A. Rutgersson, P. Yiou, L. Wu, G. Messori, G. Messori, G. Messori

“…Finally, under the high-emission scenario, the explosive cyclone and atmospheric river concurrences show an increase and model agreement over western Europe. As such, our work provides a novel statistical relation between explosive cyclones and atmospheric rivers in CMIP6 climate projections and a characterization of their joint changes in intensity and location.…”
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Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice by Seung Hee Choi, Jaechan Leem, In-Kyu Lee

“…Gemigliptin attenuated cisplatin-induced apoptotic cell death, as assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling and Western blot analysis in the kidneys. Gemigliptin also decreased the plasma levels of tumor necrosis factor-α and monocyte chemoattractant protein-1 and attenuated nuclear staining of nuclear factor kappa-B p65 in the kidneys. …”
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Work-Domain Goal Orientation: A Theoretical Framework for the Construct and Turkish Adaptation of a Work-Domain Goal Orientation Instrument by Aysun Gurol, Dilek Ilhan Findikoglu, Mehmet Gurol, Fuat Findikoglu, Mehmet Yesilkaya

“…The study provides a dual contribution by offering theoretical insights into work-domain goal orientation and delivering a psychometrically validated tool for assessing students’ readiness for professional life in a non-Western context. These findings address gaps in the literature on goal orientation and its application in diverse cultural settings, advancing both academic understanding and practical applications for educational institutions and employers. …”
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METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway by Jinghua Wang, Shushan Yan, Hongying Lu, Shufeng Wang, Donghua Xu

“…Enzyme-linked immunosorbent assay (ELISA) was adopted to estimate the generation of IL-6 and TNF-α in macrophages. Western blot and immunofluorescence were applied to evaluate the activation of NF-κB in macrophages. …”
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The Role of Dectin-1-Mediated M1 Macrophage Polarization in Cerebral Ischemia-Reperfusion Injury by Chen Zongyun, Lin Bixia, Ding Fadian, Hong Xiaoping, Chen Hongbin, Deng Yu, Liu Qicai, Ye Xiaoyi, Zeng Kai

“…The protein expression levels of dectin-1, proapoptosis molecule, and antiapoptosis molecule were measured by using western blot analysis. The brain tissue was analyzed by flow cytometry to detect the M1 macrophage levels. …”
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Knockdown of Fibromodulin Inhibits Proliferation and Migration of RPE Cell via the VEGFR2-AKT Pathway by He Hu, Shanshan Li, Jianqiao Li, Chao Huang, Fang Zhou, Li Zhao, Wenzhen Yu, Xiao Qin

“…Cell Counting Kit-8 assays, transwells, and flow cytometry analysis were used to measure cell proliferation, migration, cell cycle, and apoptosis. Western blot was used to measure expression of vascular endothelial growth factor (VEGF), VEGF receptor 2 (VEGFR2), extracellular signal-related kinase 1/2 (ERK1/2), and phosphoinositide 3 kinase (PI3K/AKT). …”
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Mechanism of engineered macrophage membrane bionic gene-carrying nanospheres for targeted drug delivery to promote wound repair in deep second-degree burns by Zhihan Zhu, Xinghua Zhu, Shichen Miao, Bolin Wang, Zihan Li, Dinghao Zhang, Shentian Zou, Yi Zhang, Qingrong Zhang, Kesu Hu

“…Immunohistochemistry and Western blotting were performed to determine the expression of relevant proteins. …”
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Multiscale Granger dependencies in the precipitation network of the island of Sicily by Vera Pecorino, Alessandro Pluchino, Alessandro Pluchino, Andrea Rapisarda, Andrea Rapisarda, Andrea Rapisarda, Kateřina Hlaváčková-Schindler

“…Our study of precipitation patterns in Sicily indicates that, since 2013, the southern regions near Mount Etna (Catania, Siracusa, and Ragusa) have been increasingly affected, while the western areas (Trapani, Palermo, and Agrigento) have been the most affected. …”
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Cultural foundations of global health: a critical examination of universal child feeding recommendations by Gabriel Scheidecker, Leberecht Funk, Nandita Chaudhary, Bambi L. Chapin, Wiebke J. Schmidt, Christine El Ouardani

“…We argue that the global promotion of Responsive Feeding—a set of allegedly best practices for child feeding promulgated by the WHO and others—is based on a tacit conviction that certain Western middle-class feeding practices are universally best, along with a promise that future evidence will demonstrate their superiority. …”
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