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  1. 3781

    A Nonstationary Daily and Hourly Analysis of the Extreme Rainfall Frequency Considering Climate Teleconnection in Coastal Cities of the United States by Lei Yan, Yuhan Zhang, Mengjie Zhang, Upmanu Lall

    Published 2025-01-01
    “…In this paper, we estimate the time-varying probability distributions for hourly and daily extreme precipitation using the Generalized Additive Model for Location Scale and Shape (GAMLSS), employing different climate indices, such as Atlantic Multi-Decadal Oscillation (AMO), the El Niño 3.4 SST Index (ENSO), Pacific Decadal Oscillation (PDO), the Western Hemisphere Warm Pool (WHWP) and other covariates. …”
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  2. 3782

    Seroprevalence against Rickettsia and Borrelia Species in Patients with Uveitis: A Prospective Survey by Kim B. Madsen, Katarina Wallménius, Åke Fridman, Carl Påhlson, Kenneth Nilsson

    Published 2017-01-01
    “…The specificity was confirmed by Western blot. Additional 28 patients had stationary titres of which eight (16.6%) had 1 : 256 or higher titre in the first serum, and another 13 patients were seronegative. …”
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  3. 3783

    A Citrus bergamia Extract Decreases Adipogenesis and Increases Lipolysis by Modulating PPAR Levels in Mesenchymal Stem Cells from Human Adipose Tissue by Debora Lo Furno, Adriana Carol Eleonora Graziano, Rosanna Avola, Rosario Giuffrida, Vincenzo Perciavalle, Francesco Bonina, Giuliana Mannino, Venera Cardile

    Published 2016-01-01
    “…Moreover, the expression of peroxisome proliferator-activated receptor gamma (PPAR-γ), adipocytes fatty acid-binding protein (A-FABP), adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), monoglyceride lipase (MGL), 5′-adenosine monophosphate-activated protein kinase (AMPK)α1/2, and pAMPKα1/2 was evaluated by Western blot analysis and the release of glycerol by colorimetric assay. …”
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  4. 3784

    Determining the crop planting calendar using T-test observation and Zoning Agro Climati and agricultural with Hotelling test in Kermanshah province by Behroz Sobhani, Vahid Safarian Zengir, Akhzar Karami

    Published 2020-06-01
    “…As a result, the central area of moderate temperatures for planting, eastern and northern areas of the southern and western areas of the province due to tropical cold and not suitable for maize cultivation.…”
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  5. 3785

    An Efficient Tourism Path Approach Based on Improved Ant Colony Optimization in Hilly Areas by Mohamed A. Damos, Wenbo Xu, Jun Zhu, Ali Ahmed, Abdolraheem Khader

    Published 2025-01-01
    “…The proposed method is implemented to develop tourist routes in the hilly Jebel Marra region in Western Sudan. A comparison is provided between the effectiveness of this approach and the GA and traditional ACO algorithms. …”
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  6. 3786

    RUSSIA AND THE WEST: A ROADMAP TO COOPERATION THROUGH FOREIGN POLICY LINKAGE OF MIDDLE EAST AND EASTERN EUROPE by L. D. Owen

    Published 2018-02-01
    “…The author argues that the NATO expansion was a political miscalculation of the Western countries. The author believes that the relations between Russia and the West can be improved through foreign policy linkage of two regions: Middle East and Eastern Europe. …”
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  7. 3787

    Molecular Mechanism of Macrophage Activation by Red Ginseng Acidic Polysaccharide from Korean Red Ginseng by Se Eun Byeon, Jaehwi Lee, Ji Hye Kim, Woo Seok Yang, Yi-Seong Kwak, Sun Young Kim, Eui Su Choung, Man Hee Rhee, Jae Youl Cho

    Published 2012-01-01
    “…According to pharmacological evaluation with specific enzyme inhibitors, Western blot analysis of intracellular signaling proteins and inhibitory pattern using blocking antibodies, ERK, and JNK were found to be the most important signaling enzymes compared to LPS signaling cascade. …”
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  8. 3788

    An Investigation of the Anticancer Mechanism of <i>Caesalpinia sappan</i> L. Extract Against Colorectal Cancer by Integrating a Network Pharmacological Analysis and Experimental Va... by Mibae Jeong, Jaemoo Chun, Sang-Min Park, Heerim Yeo, Se Won Na, In Jin Ha, Bonglee Kim, Mi-Kyung Jeong

    Published 2025-01-01
    “…CSE inhibited cell proliferation in human CRC cell lines, including HCT 116, KM12SM, HT-29, and COLO 205, and induced apoptosis via caspase 3/7 activation. Western blot analyses confirmed the modulation of critical signaling pathways, including STAT3, AKT, and mitogen-activated protein kinases. …”
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  9. 3789

    Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies by Mengdi Zhang, Haiying Qiu, Zheyi Han, Yazhong Ma, Jingjing Hou, Jingwei Yuan, Haiyan Jia, Menglu Zhou, Hongjie Lu, Yan Wu

    Published 2025-06-01
    “…The effects of lenalidomide on melanoma were further verified through Western blotting, immunohistochemistry, immunofluorescence, and quantitative real-time polymerase chain reaction,using both in vitro cell experiments and in vivo melanoma mouse models. …”
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  10. 3790

    FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway by Wen Meng, Jingfei Meng, Hong Jiang, Xing Feng, Dongshan Wei, Qingsong Ding

    Published 2020-01-01
    “…After that, tumor xenografts were used to explore the effect of FKBP4 on NSCLC tumor growth in vivo, and the phosphorylation of Akt and mTOR was measured by western blot. Results. FKBP4 was highly expressed in NSCLC tissues and cells, and its expression was closely related to NSCLC tumor size, lymph node metastasis, and patient prognosis. …”
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  11. 3791

    FOREIGN AID TO UKRAINE AFTER 2014: VOLUMES, PROJECTS AND DONORS’ MOTIVATION by O. V. Shishkina

    Published 2018-11-01
    “…Common motivation both for multilateral donors and states is to turn Ukraine into a western-like state with a transparent system of governance sensitive to foreign influence.…”
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  12. 3792

    Global trends and epidemiological impact of metabolic risk factors on atrial fibrillation and atrial flutter from 1990 to 2021 by Junqing Liang, Jun Shen, Yankai Guo, Manzeremu Rejiepu, Xiuwen Ling, Xiaoyan Wang, Yi Jian, Xing Zhang, Shijie Shao, Baopeng Tang, Ling Zhang

    Published 2025-02-01
    “…In 2021, the highest ASDR and ASMR were recorded in Australasia, North America, and Western Europe, with significant country-level variability. …”
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  13. 3793

    Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage by Yu Zhou, Kun-Lin Xiong, Sen Lin, Qi Zhong, Feng-Lin Lu, Hong Liang, Jing-Cheng Li, Jing-Zhou Wang, Qing-Wu Yang

    Published 2010-01-01
    “…Changes in HMGB1 levels were detected with ELISA and Western blot. Compared with normal controls, patients with ICH had markedly elevated levels of HMGB1, which was significantly correlated with the levels of IL-6 and TNF-α, NIHSS score at the 10th day, and mRS score at 3 months. …”
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  14. 3794

    Biological evaluation of novel 5-((1H-indol-3-yl) methyl)-2-(4-chlorobenzyl)-6-phenyl-imidazo[2,1-b][13,4]thiadiazole derivatives as novel BCL-2 specific inhibitors by Shivangi Sharma, Sadashivamurthy Shamanth, Humaira Siddiqua, Laijau Goyary, Kunigal S. Sagar, Susmita Kumari, Divya Sathees, Gudapureddy Radha, Bibha Choudhary, Sathees C. Raghavan, Kempegowda Mantelingu

    Published 2025-04-01
    “…Treatment of cancer cell lines with the Disarib derivatives, DSR 43 and 4-OCH3 led to the activation of the apoptotic pathway without generating any ROS or disrupting the mitochondrial membrane potential within the cells, leading to cell death. Western blot analysis in tandem with Annexin V/PI staining confirmed the activation of apoptosis. …”
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  15. 3795
  16. 3796

    Downregulation of TET1 Promotes Glioma Cell Proliferation and Invasion by Targeting Wnt/β-Catenin Pathway by Jianwen Ji, Qiuxiang You, Jidong Zhang, Yutao Wang, Jing Cheng, Xiangyun Huang, Yundong Zhang

    Published 2021-01-01
    “…RT-qPCR was adopted to detect the RNA level of TET1 and β-catenin; Western blot was taken to determine the expression of proteins. …”
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  17. 3797

    The Missionary-Colonial Forms of Marriages and Sexualities Within African Pentecostalism: A Sankofa-De-Colonial Perspective by Themba Shingange

    Published 2025-01-01
    “…In conclusion, the study emphasized the need to delink from Western conceptualizations by rethinking African marriages and sexualities. …”
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  18. 3798

    From Policy to Practice: Assessing Carbon Storage in Fujian Province Using Patch-Generating Land Use Simulation and Integrated Valuation of Ecosystem Services and Tradeoffs Models by Qin Nie, Wang Man, Zongmei Li, Xuewen Wu

    Published 2025-01-01
    “…Key conservation areas, including 12 priority districts, were identified in the western and northwestern regions, while coastal urban areas, comprising 31 vulnerable districts, face significant carbon storage losses. …”
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  19. 3799

    Exploring the Node Importance and Its Influencing Factors in the Railway Freight Transportation Network in China by Qipeng Sun, Xiaozhuang Guo, Wenjing Jiang, Haiying Ding, Tingzhen Li, Xingbo Xu

    Published 2019-01-01
    “…At the same time, the PageRank values of many provinces in the central and western regions significantly increased, and those provinces exhibited more frequent exchanges of goods with other provinces and closer economic ties with other regions. (2) The traffic fixed asset investments and the population density have the most obvious influences on the importance of the provincial nodes with a positive effect. …”
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  20. 3800

    Glycyrrhizin Attenuates Toll Like Receptor-2, -4 and Experimental Vasospasm in a Rat Model by Chih-Zen Chang, Shu-Chuan Wu, Aij-Lie Kwan

    Published 2014-01-01
    “…Basilar arteries were harvested to examine TLRs mRNA and protein (rt-PCR and western blot) and CSF cytokines (rt-PCR). Morphologically, deformed endothelium, tortuous elastic lamina, and smooth muscle necrosis were observed in the SAH rats, but were absent in the glycyrrhizin pretreatment group. …”
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