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3781
A Nonstationary Daily and Hourly Analysis of the Extreme Rainfall Frequency Considering Climate Teleconnection in Coastal Cities of the United States
Published 2025-01-01“…In this paper, we estimate the time-varying probability distributions for hourly and daily extreme precipitation using the Generalized Additive Model for Location Scale and Shape (GAMLSS), employing different climate indices, such as Atlantic Multi-Decadal Oscillation (AMO), the El Niño 3.4 SST Index (ENSO), Pacific Decadal Oscillation (PDO), the Western Hemisphere Warm Pool (WHWP) and other covariates. …”
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3782
Seroprevalence against Rickettsia and Borrelia Species in Patients with Uveitis: A Prospective Survey
Published 2017-01-01“…The specificity was confirmed by Western blot. Additional 28 patients had stationary titres of which eight (16.6%) had 1 : 256 or higher titre in the first serum, and another 13 patients were seronegative. …”
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3783
A Citrus bergamia Extract Decreases Adipogenesis and Increases Lipolysis by Modulating PPAR Levels in Mesenchymal Stem Cells from Human Adipose Tissue
Published 2016-01-01“…Moreover, the expression of peroxisome proliferator-activated receptor gamma (PPAR-γ), adipocytes fatty acid-binding protein (A-FABP), adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), monoglyceride lipase (MGL), 5′-adenosine monophosphate-activated protein kinase (AMPK)α1/2, and pAMPKα1/2 was evaluated by Western blot analysis and the release of glycerol by colorimetric assay. …”
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3784
Determining the crop planting calendar using T-test observation and Zoning Agro Climati and agricultural with Hotelling test in Kermanshah province
Published 2020-06-01“…As a result, the central area of moderate temperatures for planting, eastern and northern areas of the southern and western areas of the province due to tropical cold and not suitable for maize cultivation.…”
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3785
An Efficient Tourism Path Approach Based on Improved Ant Colony Optimization in Hilly Areas
Published 2025-01-01“…The proposed method is implemented to develop tourist routes in the hilly Jebel Marra region in Western Sudan. A comparison is provided between the effectiveness of this approach and the GA and traditional ACO algorithms. …”
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3786
RUSSIA AND THE WEST: A ROADMAP TO COOPERATION THROUGH FOREIGN POLICY LINKAGE OF MIDDLE EAST AND EASTERN EUROPE
Published 2018-02-01“…The author argues that the NATO expansion was a political miscalculation of the Western countries. The author believes that the relations between Russia and the West can be improved through foreign policy linkage of two regions: Middle East and Eastern Europe. …”
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3787
Molecular Mechanism of Macrophage Activation by Red Ginseng Acidic Polysaccharide from Korean Red Ginseng
Published 2012-01-01“…According to pharmacological evaluation with specific enzyme inhibitors, Western blot analysis of intracellular signaling proteins and inhibitory pattern using blocking antibodies, ERK, and JNK were found to be the most important signaling enzymes compared to LPS signaling cascade. …”
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3788
An Investigation of the Anticancer Mechanism of <i>Caesalpinia sappan</i> L. Extract Against Colorectal Cancer by Integrating a Network Pharmacological Analysis and Experimental Va...
Published 2025-01-01“…CSE inhibited cell proliferation in human CRC cell lines, including HCT 116, KM12SM, HT-29, and COLO 205, and induced apoptosis via caspase 3/7 activation. Western blot analyses confirmed the modulation of critical signaling pathways, including STAT3, AKT, and mitogen-activated protein kinases. …”
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3789
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies
Published 2025-06-01“…The effects of lenalidomide on melanoma were further verified through Western blotting, immunohistochemistry, immunofluorescence, and quantitative real-time polymerase chain reaction,using both in vitro cell experiments and in vivo melanoma mouse models. …”
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3790
FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway
Published 2020-01-01“…After that, tumor xenografts were used to explore the effect of FKBP4 on NSCLC tumor growth in vivo, and the phosphorylation of Akt and mTOR was measured by western blot. Results. FKBP4 was highly expressed in NSCLC tissues and cells, and its expression was closely related to NSCLC tumor size, lymph node metastasis, and patient prognosis. …”
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3791
FOREIGN AID TO UKRAINE AFTER 2014: VOLUMES, PROJECTS AND DONORS’ MOTIVATION
Published 2018-11-01“…Common motivation both for multilateral donors and states is to turn Ukraine into a western-like state with a transparent system of governance sensitive to foreign influence.…”
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3792
Global trends and epidemiological impact of metabolic risk factors on atrial fibrillation and atrial flutter from 1990 to 2021
Published 2025-02-01“…In 2021, the highest ASDR and ASMR were recorded in Australasia, North America, and Western Europe, with significant country-level variability. …”
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3793
Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage
Published 2010-01-01“…Changes in HMGB1 levels were detected with ELISA and Western blot. Compared with normal controls, patients with ICH had markedly elevated levels of HMGB1, which was significantly correlated with the levels of IL-6 and TNF-α, NIHSS score at the 10th day, and mRS score at 3 months. …”
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3794
Biological evaluation of novel 5-((1H-indol-3-yl) methyl)-2-(4-chlorobenzyl)-6-phenyl-imidazo[2,1-b][13,4]thiadiazole derivatives as novel BCL-2 specific inhibitors
Published 2025-04-01“…Treatment of cancer cell lines with the Disarib derivatives, DSR 43 and 4-OCH3 led to the activation of the apoptotic pathway without generating any ROS or disrupting the mitochondrial membrane potential within the cells, leading to cell death. Western blot analysis in tandem with Annexin V/PI staining confirmed the activation of apoptosis. …”
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3795
Development and Application of an Indirect Enzyme‐Linked Immunosorbent Assay Based on a Recombinant Matrix Protein for the Serological Study of Porcine Deltacoronavirus in Mexican...
Published 2024-11-01“…The kappa index calculated a nearly perfect agreement (0.8831) compared to the Western blot (gold standard test), suggesting acceptable statistical value support. …”
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3796
Downregulation of TET1 Promotes Glioma Cell Proliferation and Invasion by Targeting Wnt/β-Catenin Pathway
Published 2021-01-01“…RT-qPCR was adopted to detect the RNA level of TET1 and β-catenin; Western blot was taken to determine the expression of proteins. …”
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3797
The Missionary-Colonial Forms of Marriages and Sexualities Within African Pentecostalism: A Sankofa-De-Colonial Perspective
Published 2025-01-01“…In conclusion, the study emphasized the need to delink from Western conceptualizations by rethinking African marriages and sexualities. …”
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3798
From Policy to Practice: Assessing Carbon Storage in Fujian Province Using Patch-Generating Land Use Simulation and Integrated Valuation of Ecosystem Services and Tradeoffs Models
Published 2025-01-01“…Key conservation areas, including 12 priority districts, were identified in the western and northwestern regions, while coastal urban areas, comprising 31 vulnerable districts, face significant carbon storage losses. …”
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3799
Exploring the Node Importance and Its Influencing Factors in the Railway Freight Transportation Network in China
Published 2019-01-01“…At the same time, the PageRank values of many provinces in the central and western regions significantly increased, and those provinces exhibited more frequent exchanges of goods with other provinces and closer economic ties with other regions. (2) The traffic fixed asset investments and the population density have the most obvious influences on the importance of the provincial nodes with a positive effect. …”
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3800
Glycyrrhizin Attenuates Toll Like Receptor-2, -4 and Experimental Vasospasm in a Rat Model
Published 2014-01-01“…Basilar arteries were harvested to examine TLRs mRNA and protein (rt-PCR and western blot) and CSF cytokines (rt-PCR). Morphologically, deformed endothelium, tortuous elastic lamina, and smooth muscle necrosis were observed in the SAH rats, but were absent in the glycyrrhizin pretreatment group. …”
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