Quercetin inhibits the biological activity of endometrial cancer by regulating autophagy: A network pharmacology analysis and cellular experimental validation by Lingchen Yang, Hongwei Ma

“…Cell Counting Kit-8 and flow cytometry assays were used to evaluate cell proliferation and apoptosis; cell invasive and migratory abilities were assessed by Transwell and wound healing assays, respectively; the observation of the cell ultrastructure was performed by transmission electron microscopy; the relative protein expressions were measured by the western blot assay. Depending on results, Que. exhibited antitumor effects by stimulating autophagy via regulating the ATF5/JUN/PI3K/AKT/mTOR pathway in EC.…”
Get full text

Rosavin exerts an antitumor role and inactivates the MAPK/ERK pathway in small-cell lung carcinoma in vitro by Liu Rui, Jiang Cuihong, Zhao Zhizheng, Lv Yutong, Wang Gaoxing

“…Besides, protein levels of p-ERK, ERK, p-MEK and MEK were determined using Western blot analysis. Rosavin repressed the viability and clone formation of SCLC cells, and promoted apoptosis and G0/G1 arrest of SCLC cells. …”
Get full text

Research on the Simulation Application of Data Mining in Urban Spatial Structure by Jun Zhang, Xin Sui, Xiong He

“…In this study, 705,747 POI (Point of Interest) were used to conduct simulation analysis of western cities in China by mining the data of online maps. …”
Get full text

Spatiotemporal Variation of Frost within Growing Periods by Mokhele Edmond Moeletsi, Mphethe Isaac Tongwane

“…The results show high spatial and temporal variability of frost within the different growing periods. The western, central, northern, and northwestern parts of the province have the longest planting window for all the growing lengths from mid-October to mid-January. …”
Get full text

Integrating Islamic Values in English Learning through Islamic Stories: Students’ Perspective by Lutfi Aprilia Rahmatika, Lidiyatul Izzah Izzah

“…Most of them agreed that the learning was fun, enjoyable, helped them to understand English better, enriched their vocabularies and made them able to differentiate between Western and Islamic cultures and apply all good lessons in their daily live. …”
Get full text

The Pact of Baghdad on Account of its Effect to Relationship of Turkish - Arabian by Mustafa Bostancı

“…Effects of Baghdad Pact, which alienated Turkey from the region while reinforcing anti-western camp, on Arabian society were not positive at all; particularly Egypt protested against this pact accepting it to be the heaviest strike on Arabian Union. …”
Get full text

Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome by Xu Boqun, Dai Xiaonan, Cui YuGui, Gao Lingling, Dai Xue, Chao Gao, Diao Feiyang, Liu Jiayin, Li Gao, Mei Li, Yuan Zhang, Xiang Ma

“…The expression levels of SET protein were analyzed by Western Blot. Result. SET protein was expressed predominantly in the theca cells and oocytes of human ovarian follicles in both PCOS ovarian tissues and normal ovarian tissues. …”
Get full text

Migrants' rights: problems remain by N. A. Voronina

“…The study notes that in recent years, Western countries have been reviewing approaches to state regulation of the social sphere, which in some cases discriminates towards refugees and displaced persons from other countries. …”
Get full text

Voyages en Shangrila : le marché « in situ » des objets d’art primitif d’Himalaya by Gisèle Krauskopff

“…This journey back to where these objects were negotiated shows how classificatory reconfigurations operate, first on the local market and then in Western galleries, and the role played by dealers and collectors in the birth of a Himalayan primitive art.…”
Get full text

Examining Hotel Standards as a Promotional Strategy for Tourism Growth: A Case Study of Hotels in Kisoro District. by Mwesigye, Cresstus

“…The study recommends that more efforts have to be made to enhance the success of small and medium hotel operators in western Uganda and this should be emphasized in the provision of assistance in marketing and finance.…”
Get full text

Master of Medicine: Paediatrics and Child Health by Kabale University

“…Child health related conditions account for a significant amount of the disease burden in south western Uganda where Kigezi region and Kabale University are situated. …”
Get full text

Kabale University Interdisciplinary Research Journal (KURJ) by Kaaya, Siraje, George Stanley, Kinyata

“…The papers include: Reverse logistics and environmental sustainability in selected manufacturing entities in Kampala district, Uganda; Antiplasmodial compounds from Millettia dura; Resource mobilisation and allocation priorities on knowledge production in universities in Uganda: an empirical study; Epidemiology and causes of common soccer injuries during university games in Uganda; Micro-credit institution’s services and sustainability of micro, small and medium-scale enterprises during Covid-19 pandemic in Kigezi region south western Uganda; Transformational Leadership style and occupational stress among primary School Teachers in Tanzania; Citrus fruit farmers’ Adaptation Capacities to Climate Variability in Ngora district, Eastern Uganda; Developing metacognition in pre-primary childhood education in Nigeria and Uganda; and Mentorship and supervision in Ugandan higher education Institutions universities: challenges and prospects. …”
Get full text

Auricular Acupuncture for Perioperative Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zhou Y, Bao Q, Yang C, Li S, Yin Z, Xiong J, Sun M, Yang J, Liu F, Liang F

“…Yan Zhou,1,* Qiongnan Bao,1,* Chen Yang,1,* Shuhao Li,1,* Zihan Yin,1 Jian Xiong,1 Mingsheng Sun,1 Jiao Yang,2 Fang Liu,3 Fanrong Liang1 1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 3Department of Integrated Chinese and Western Medicine, Sichuan Cancer Hospital, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fanrong Liang, Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, People’s Republic of China, Email acuresearch@126.com Fang Liu, Department of Integrated Chinese and Western Medicine, Sichuan Cancer Hospital, Chengdu, Sichuan, 610041, People’s Republic of China, Email liufang@scszlyy.org.cnPurpose: We conducted a more comprehensive systematic review and meta-analysis to evaluate the effectiveness of auricular acupuncture (AA) in perioperative pain management.Methods: Randomized controlled trials (RCTs) findings were retrieved from the Embase, Cochrane Central Register of Controlled Trials, PubMed, Web of Science, Chinese Biomedical Literature Database, Wanfang, VIP, and China National Knowledge Infrastructure databases from their inception to March 2024 using the search terms “pain”, “auriculotherapy”, and “randomized controlled trial”. …”
Get full text

Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroentero... by Mark S Silverberg, Jack Satsangi, Tariq Ahmad, Ian DR Arnott, Charles N Bernstein, Steven R Brant, Renzo Caprilli, Jean-Frédéric Colombel, Christoph Gasche, Karel Geboes, Derek P Jewell, Amir Karban, Edward V Loftus, A Salvador Peña, Robert H Riddell, David B Sachar, Stefan Schreiber, A Hillary Steinhart, Stephan R Targan, Severine Vermeire, Bryan F Warren

Get full text

MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1 by Kaiqiang Meng, Jian Song, Fan Qi, Jiamin Li, Zhichao Fang, Liang Song

“…Perform bioinformatics analysis using the TCGA database to investigate the expression of MT1G in GC. RT-qPCR and Western blot were used to detect the expression of MT1G, ferroptosis related proteins, autophagy related proteins and ARNTL clock autophagy related proteins in Hgc27, MKN45 and AGS cell lines. …”
Get full text

Precipitation changes alter the structure, species composition and interspecific relationships of desert steppe plant communities by Kechen Song, Hao Zhang, Haiying Hu, Yingzhong Xie, Xiaona Zhao, Yiyin Zhang, Jiayi Yong, Wenhui Deng, Siyu Guan

Get full text

Evaluation of spinal deformity and its progression in pyogenic spondylodiscitis: A retrospective MRI study of 59 cases by Andreas Kramer, Jonathan Neuhoff, Santhosh G. Thavarajasingam, Rebecca Sutherland, Hugh McCaughan, Benjamin Davies, Ehab Shiban, Florian Ringel, Andreas K. Demetriades

Get full text

Establishment of a prognostic signature and immune infiltration characteristics for uterine corpus endometrial carcinoma based on a disulfidptosis/ferroptosis-associated signature by Yong Huang, Huibin Li, Zhifu Wei, Wanshan He, Bin Chen, Shuang Cheng, Zhifang Zhao, Lv Deng, Lv Deng, Xiaohua Chen, Yu Lin, Yu Lin, Xiaoshan Hong, Xiaoshan Hong

Get full text

Expression pattern of Calbindin-D28k, NeuN proteins, ATOH1 and EN2 genes in the human fetal cerebellum by Phanindra Prasad Poudel, Arnab Ghosh, Chacchu Bhattarai, Saman Pradhan, Nirmal Panthi, Dela Singh Joshi, Shanti Khadka, Sandhya Kumari, Guruprasad Kalthur, R. Vani Lakshmi, Sneha Guruprasad Kalthur

Get full text

Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: An individual-based modeling s... by Matthew D Hickey, James Ayieko, Jane Kabami, Asiphas Owaraganise, Elijah Kakande, Sabina Ogachi, Colette I Aoko, Erick M Wafula, Norton Sang, Helen Sunday, Paul Revill, Loveleen Bansi-Matharu, Starley B Shade, Gabriel Chamie, Laura B Balzer, Maya L Petersen, Diane V Havlir, Moses R Kamya, Andrew N Phillips

“…We evaluated the cost-effectiveness of population-level hypertension screening and implementation of chronic care clinics across eastern, southern, central, and western Africa.<h4>Methods and findings</h4>We conducted a modeling study to simulate hypertension and CVD across 3,000 scenarios representing a range of settings across eastern, southern, central, and western Africa. …”
Get full text