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    miR‐224‐5p Suppresses Non‐Small Cell Lung Cancer via IL6ST‐Mediated Regulation of the JAK2/STAT3 Pathway by Jiao Tian, Yiming He, Zihui Zhang, Yuxin Zhu, Haixia Ren, Liang Zhang, Lei Li, Wei Li, Weidong Zhang, Ting Xiao, Honggang Zhou, Xiaoping Li

    Published 2025-01-01
    “…Then, we used MTT assays, wound healing assays, Transwell assays, and western blotting to evaluate the effects of miR‐224‐5p on NSCLC cell proliferation, migration, invasion, and epithelial–mesenchymal transition (EMT). …”
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  14. 2614

    The Impact of the Urban Heat Island Effect on Ground-Level Ozone Pollution in the Sichuan Basin, China by Xingtao Song, Haoyuan Shi, Langchang Jin, Sijing Pang, Shenglan Zeng

    Published 2024-12-01
    “…In terms of spatial variation, the overall distribution is highest in western Sichuan, second highest along the Sichuan River, and lowest in central Sichuan. (2) There are significant regional differences in UHII across Sichuan, with medium heat islands (78.63%) dominating western Sichuan, weak heat islands (82.74%) along the Sichuan River, and no heat island (34.79%) or weak heat islands (63.56%) in central Sichuan. …”
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  15. 2615

    miR-129-5p Promotes Osteogenic Differentiation of BMSCs and Bone Regeneration via Repressing Dkk3 by Changming Zhao, Yulin Gu, Yan Wang, Qiaozhen Qin, Ting Wang, Meng Huang, Heyang Zhang, Yannv Qu, Jingwen Zhang, Zhangzhen Du, Xiao-Xia Jiang, Lulu Xu

    Published 2021-01-01
    “…The expression of osteogenic genes (Runx2, Bmp2, and OCN) was examined via quantitative RT-PCR and western blot. A mouse model of calvaria defect was investigated by Micro-CT, immunohistochemistry, and histological examination. …”
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  16. 2616

    Taohong Siwu Decoction Exerts a Beneficial Effect on Cardiac Function by Possibly Improving the Microenvironment and Decreasing Mitochondrial Fission after Myocardial Infarction by Zhi-rong Luo, Han Li, Zhong-xin Xiao, Shui-jin Shao, Tian-tian Zhao, Yue Zhao, Fang-fang Mou, Bo Yu, Hai-dong Guo

    Published 2019-01-01
    “…Cell apoptosis in the infarcted area was assessed by TUNEL staining, and the p-Akt level was detected using the western blot assay. The mitochondrial ROS production was measured using MitoSOX staining, and mitochondrial dynamics and mitophagy were evaluated with western blotting 7 days after THSWD treatment. …”
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  17. 2617

    The burden and outcomes of firearm injuries at two district-level emergency centres in Cape Town, South Africa: A descriptive analysis by L Bush, C Hendrikse, C Van Koningsbruggen, K Evans

    Published 2024-02-01
    “…To describe the burden of patients with firearm injuries and their outcomes at district-level emergency centres in the Western Cape. Methods. This study was a retrospective analysis of a prospectively collected database. …”
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  18. 2618

    Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes by Yu Jung Heo, Sung-E Choi, Ja Young Jeon, Seung Jin Han, Dae Jung Kim, Yup Kang, Kwan Woo Lee, Hae Jin Kim

    Published 2019-01-01
    “…We assessed the intracellular signaling molecules including STAT3, NF-κB, IKK, p38, JNK, and ERK by western blotting. We treated HepG2 cells with both visfatin and either AG490 (a JAK2 inhibitor) or Bay 7082 (an NF-κB inhibitor); we examined proinflammatory cytokine mRNA levels using RT-PCR and insulin signaling using western blotting. …”
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  19. 2619

    An Analysis of Land Use Conflicts and Strategies in the Harbin–Changchun Urban Agglomeration Based on the Production–Ecological–Living Space Theory and Patch-Generating Land Use Si... by Xiaomeng Wang, Yanjun Zhang, Xiaoyan Li, Shuwen Cao

    Published 2025-01-01
    “…The results indicate the following: (1) From 2000 to 2020 and different scenarios in 2030, the PELS of the HCUA is dominated by forest ecological space (E1) and agricultural production space (P1), with no substantial alterations in the overall spatial distribution of the PELS. (2) Absolute and relative conflicts between 2000 and 2020 are mainly concentrated in the plains of the western regions, characterized by conflicts arising from the encroachment of living space on production space; however, absolute conflicts have declined annually, accompanied by a notable enhancement in ecological quality. (3) The spatial pattern of absolute conflicts in 2030 exhibits minimal variation, illustrating higher values in the western regions compared to the eastern parts, with living space surpassing ecological space and plains showing higher conflict values than mountains. …”
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  20. 2620

    Oxaliplatin-Loaded Chitosan Nanoparticles Decorated with Cetuximab Single-Chain Variable Fragment for Human Colorectal Cancer Treatment by Khadijeh Falahzadeh, Fariba Esmaeili, Leila Nematollahi, Elham Bayat, Mehdi Khoobi, Mohammadali Mazloomi, Masumeh Jalalvand, Reza Faridi Majidi, Babak Negahdari

    Published 2024-09-01
    “…Encapsulationefficiency percentage (EE%) and oxaliplatin release rate were evaluated. Western blot and cell-based ELISA confirmed scFvproduction and its binding ability to EGFR, respectively. …”
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