Enhanced expression of ten‐eleven translocation 1 reverses gemcitabine resistance in cholangiocarcinoma accompanied by a reduction in P‐glycoprotein expression by Chuanxu Wang, Hua Ye, Lei Zhang, Yayu Cheng, Shifeng Xu, Ping Zhang, Zijie Zhang, Jimin Bai, Fangkang Meng, Lin Zhong, Guangjun Shi, Hao Li

“…And then, the possible effect of TET1 on the expression of P‐gp was examined by western blot analysis. Xenograft tumor experiment was conducted to confirm the association between TET1 and P‐gp expression under gemcitabine chemoresistance. …”
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Law enforcement activity, globalization and social morality in frameworks of mass culture (On the Example of Modern European TV-Shows on Law-Enforcements. Part 2) by Vovk V.

“…Cultural and semiotic methodological approaches assisted in carrying out an analysis of modern series on law enforcement officers to find in them the transmission of the main moral values of Western European society, which include humanism, equality, tolerance, and inclusion. …”
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Genotypic and ecological variability of zinc content in the grain of spring bread wheat varieties in the international nursery KASIB by V. P. Shamanin, P. Flis, T. V. Savin, S. S. Shepelev, O. G. Kuzmin, A. S. Chursin, I. V. Pototskaya, I. E. Likhenko, I. Yu. Kushnirenko, A. A. Kazak, V. A. Chudinov, T. V. Shelaeva, A. I. Morgounov

“…Spring bread wheat is the staple crop in Western Siberia and Kazakhstan, a significant portion of which goes for export. …”
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WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway by Dongmei Cheng, Yang Bao, Xue Wang, Haidong Xiang, Tianyuan Guo, Yong Du, Zhiyong Zhang, Han Guo

“…Changes in protein expression related to the FOXO1 signaling pathway, cell cycle, and apoptosis were evaluated using western blotting (WB). Results Differentially expressed genes (DEGs) associated with DPSC cementogenic differentiation were predominantly enriched in crucial pathways such as the signaling pathway, cell apoptosis, and Wnt signaling pathway. …”
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Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia by Rong Lin, Rong Lin, XiaoYing Weng, XiaoYing Weng, Liang Lin, Liang Lin, XuYang Hu, XuYang Hu, ZhiYan Liu, ZhiYan Liu, Jing Zheng, Jing Zheng, FenFang Shen, FenFang Shen, Rui Li, Rui Li

“…Immunofluorescence, RT-qPCR, and Western blot confirmed reduced expression of SLC25A5, MFF, and PMAIP1 in PE, whereas ACSF2 was significantly upregulated.ConclusionThese four mtPCD-related biomarkers may play a pivotal role in PE pathogenesis, offering new perspectives on the disease’s diagnostic and mechanistic pathways.…”
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A tendency towards leaf rust resistance decrease in common wheat introgression lines with genetic material from Aegilops speltoides Tausch by L. Ya. Plotnikova, L. V. Meshkova, E. I. Gultyaeva, O. Р. Mitrofanova, I. F. Lapochkina

“…The trend of overcoming of resistance to leaf rust of introgres­sive lines and varieties with Ae. speltoides genes should be taken into consideration in common wheat breeding in Western Siberia.…”
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False Alarm Causes and Wind Field Sensitivity Analysis of a Severe Rainfall Event in the Guangdong-Hong Kong-Macao Greater Bay Area Urban Cluster by Lan Zhang, Jiawen Zheng, Huaiyu Li, Rui Yu, Lei Wei, Yufei Zhang

“…The results indicate that the warm and moist airflow transported by the low-level jet stream was intercepted by the upstream MCS (mesoscale convective system) along the coastal area of western Guangdong, and inadequate conditions of negative vorticity dynamics led to insufficient moisture, thermodynamic, and dynamic conditions over the urban cluster, preventing the triggering of heavy precipitation. …”
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Demographic and Clinical Characteristics of Patients with Corneal Ectasia at Multiple Medical Centers in Saudi Arabia: A Hospital-based Study by Waleed Alghamdi, Sulaiman Aldakhil, Saif Hassan Alrasheed, Kareem Allinjawi, Mustafa Abdu, Raghda F. Mutwaly, Khaled Al Rashah, Hani M. Ghazal, Ghassan H. Radwan, Naveen Kumar Challa

“…The mean age of onset was 7.1 years, ranging from 2–32 years, which was higher among patients from the western region. Regarding severity, 230 (53.5%) eyes presented in the initial stages, while 36 (8.4%) were in the severe stage with no significant difference between the regions studied. …”
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DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway by Hui Wang, Shen Luo, Yue Yin, Yang Liu, Xiaomei Sun, Ling Qiu, Xin Wu

“…Rescue experiments in which SREBP1 was overexpressed in DLAT-silenced cells were carried out. Western blot analysis was performed to determine whether the JAK2/STAT5 signaling pathway was involved in DLAT-regulated SREBP1 expression. …”
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Effect of High-Fat Diet on Spatial Learning and Memory and Regulatory Role of N-Methyl-D-Aspartate Receptors in the Dentate Gyrus by LIU Huaying, DONG Wei, ZHANG Zihan, LI Yingshun, JIN Qinghua

“…The Morris water maze (MWM) test was used to evaluate the spatial learning and memory capacity of the rats; Western blot was used to detect the expression of phosphorylated Ca2+/calmodulin dependent protein kinase II (p-CaMKII) and cAMP-response element binding protein (p-CREB), pro-inflammatory cytokines, including interleukin-6 (IL-6) and IL-1β in the hippocampal dentate gyrus (DG); the expression of ionized calcium binding adapter molecule 1 (Iba1) in the DG were observed by Western blot and immunohistochemistry. …”
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Open-ended narrative and moral formation by J. Klaasen

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Treatment of Common Femoral Artery Pseudoaneurysm: A Novel Approach Utilizing a VASCADE Percutaneous Closure Device by Mark Dalvin, Brandon Dessecker, Eugene Vitvitsky

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Basic Experimental and Clinical Advances in the Mechanisms Underlying Abnormal Pregnancy Outcomes by Timothy R. H. Regnault, Mark J. Nijland, Helen Budge, Janna L. Morrison

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The Addition of Salmeterol 50 µg Bid to Anticholinergenic Treatment in Patients with COPD: A Randomized Placebo Controlled Trial by Kenneth R Chapman, Peter Arvidsson, AG Chuchalin, DP Dhillon, Peter Faurschou, Roger S Goldstein, AF Kuipers

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User Assessment in Serious Games and Technology-Enhanced Learning by Francesco Bellotti, Bill Kapralos, Kiju Lee, Pablo Moreno-Ger

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Study of the Greater Caucasus glaciers and forest distribution routes by Baghirov Hussein

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On a non-self adjoint expansion formula by D. Naylor

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The role of mountain culture in the development of tourism: The example of Azerbaijan by Jabarova T. M.

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Protecting Wetlands for our Common Future: Aspirations and Insights from Two Key Countries of the Global South by Héctor Aponte, Bramley Jemain Lemine, Shaddai Daniel

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The District Health System must become a learning health system by L Gilson, O S Motshweneng

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