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681
Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery
Published 2020-01-01“…The expression levels of smooth muscle alpha-actin (a-SMA) and procollagen I (COL1A1) were assessed by RT-PCR and western blot analysis. PFD suppressed hypoxia-induced proliferation and migration of HPAAFs. …”
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682
Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway
Published 2013-01-01“…Changes in mRNA and protein expression of Δ6D were then determined using real-time RT-PCR and Western blot, respectively. The expression of Δ6D (P<0.01) increased following treatment with PPARδ agonist both at mRNA and protein levels, whereas no significant change was observed after treatment with MEK/ERK1/2 pathway inhibitor. …”
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683
Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway
Published 2014-01-01“…The effect of LA on high glucose-induced cell proliferation, fibronectin (FN), and collagen type I (collagen-I) expression and its mechanisms were examined in cultured rat mesangial cells by methylthiazol tetrazolium (MTT) assay, flow cytometry, ELISA assay, and western blot, respectively. …”
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684
Cellular Contractility Profiles of Human Diabetic Corneal Stromal Cells
Published 2021-01-01“…Primary human corneal fibroblasts from healthy, Type 1 DM (T1DM), and Type 2 DM (T2DM) donors were cultured using an established 3D collagen gel model. …”
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685
SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1
Published 2020-06-01“…Cell cycle progression was analyzed using propidium iodide (PI) staining, and protein levels were assayed by Western blot analysis. Our results showed low expression of SOX7 in PCa tissues/cells compared to their non-tumorous counterparts/RWPE-1 cells. …”
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686
RELATIONSHIP BETWEEN NATIVE INTELLIGENCE (NI) AND ARTIFICIAL INTELLIGENCE (AI): AN OVERVIEW
Published 2024-03-01“…Western Ideologists tend to attribute Native Intelligence (NI) to Africans / third-word concepts, indistinctly fixed to value and belief that aided social cultural, religious, political economic, spiritual evolution, and ancient societies, However, the Emergence of Artificial intelligence (AI) being the capacity of a computer system or machine to mimic human cognitive such as learning and solving problems, through a computer system that uses mathematics and logic, to simulate the reasoning ability of man, through the process of learning from new information, and transforming such information into actions, by making decisions that has increasingly enhanced the quality of human life. …”
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687
Astrocytic Acid-Sensing Ion Channel 1a Contributes to the Development of Epileptic Cognitive Impairment
Published 2025-01-01“…Behavioral assessments were conducted using the Morris water maze (MWM). Western blotting and immunofluorescence were applied to evaluate ASIC1a and <i>Gfap</i> expression while analyzing intracellular calcium and extracellular glutamate (Glu) concentrations in primary cultured astrocytes isolated from the brains of 1 to 3-day-old mice and treated LPS. …”
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688
GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway
Published 2024-01-01“…Hierarchical cluster analysis was used to evaluate pyrimidine metabolism. Cultured STAD cells assessed the proliferation of STAD and upregulation of GPX3 expression by CCK8 and flow cytometry. …”
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689
CHRISTIAN THINKERS ON INTERNATIONAL RELATIONS (REINHOLD NIEBUHR AND GIORGIO LA PIRA)
Published 2013-08-01“…The author analyzes their views on international relations, in particularly on the western policy towards the Soviet Union, the use of nuclear weapons, the war in Vietnam and the communist issue. …”
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690
Acceptability and feasibility of pre-exposure prophylaxis for bacterial STIs: a systematic review.
Published 2025-01-01“…Similarly, the perspectives of populations beyond GBMSM have been omitted, and there is little understanding of the impact of their differing socio-cultural contexts around sex-related behaviour and Western pharmaceutical healthcare interventions on their acceptance and uptake.…”
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691
Directions for the implementation of foreign experience in operative and investigative counteraction to intentional murders by criminal police units (on the example of Canada and t...
Published 2022-09-01“…Modern criminology distinguishes Anglo-American, Western European, East Asian, socialist, Muslim and mixed criminological systems. …”
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692
RETRACTED: The role of biofield energy treatment on psychological symptoms, mental health disorders, and stress‐related quality of life in adult subjects: A randomized controlled c...
Published 2023-05-01“…Abstract Background Western and Eastern cultures have practiced biofield energy therapy for thousands of years, but empirical research on effectiveness of this therapy is relatively nascent. …”
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693
Mechanical Stress-Induced IGF-1 Facilitates col-I and col-III Synthesis via the IGF-1R/AKT/mTORC1 Signaling Pathway
Published 2021-01-01“…First, LFCs were isolated from 9 patients and cultured with or without mechanical stress exposure for different times. …”
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694
‘Customary’ use of stick tools by chimpanzees in Bulindi, Uganda: update and analysis of digging techniques from behavioural observations
Published 2020-07-01“…Compared to other geographical regions, chimpanzees (Pan troglodytes schweinfurthii) in mid-western Uganda generally have small toolkits, with one long-term study group – the Sonso community in Budongo Forest – exhibiting no foraging stick use whatsoever. …”
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695
THE DESIRE FOR RECOGNITION IN THE CONTEXT OF FRANCIS FUKUYAMA’S UNIVERSAL HISTORY
Published 2016-12-01“…Francis Fukuyama in his famous book “The End of History and the Last Man” assumes that human history should be considered as the battle of ideologies that reaches its goal in the universalization of Western liberal democracy. Author’s ideas have gained many supporters. …”
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696
lncRNA NEAT1 Downregulation Ameliorates the Myocardial Infarction of Mice by Regulating the miR-582-5p/F2RL2 Axis
Published 2022-01-01“…The expressions of F2RL2, miR-582-5p, and nuclear paraspeckle assembly transcript 1 (NEAT1) in myocardial tissues and HCMs were quantified by qRT-PCR or Western blot. Results. NEAT1 sponged miR-582-5p which targeted F2RL2. …”
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697
In Vitro Study on the Regulation of Annexin IV and VEGF by hCG in the Human Endometrium
Published 2020-01-01“…Annexin IV and VEGF were analyzed by qRT-PCR (mRNA), western blot (proteins), and immunohistochemistry (proteins). …”
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698
Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation
Published 2019-01-01“…Rg1 was applied to cells or animals at indicated dosage. Apoptosis of cultured cells was quantified by flow cytometry, along with ELISA for inflammatory cytokines in supernatant. …”
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699
Teachers’ responses to racism and racist bullying in Dutch primary schools
Published 2025-01-01“…BackgroundEarly in life, children with a non-White skin color, or a non-Western cultural or religious background, are susceptible of experiencing acts of racism. …”
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700
Resveratrol Induces Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Neuron-Like Cells
Published 2017-01-01“…Nestin, neuron-specific enolase (NSE), and glial fibrillary acidic protein (GFAP) were detected by immunocytochemistry, Western blotting, and real time RT-PCT. The cultured hUC-MSCs were treated with resveratrol at different concentrations (0, 7.5, 15.0, and 30.0 mg/L). …”
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