Editorial for special issue on Big Data and knowledge extraction for Cyber-Physical Systems 2016 by Xiuzhen Cheng, Yunchuan Sun, Zhipeng Cai, Jiguo Yu, Donghyun Kim, Jin Liu

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Totally disconnected compactifications by Parfeny P. Saworotnow

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Obesity-Related Metabolic Syndrome and Vascular Complications by Manfredi Tesauro, Micaela Iantorno, Umberto Campia

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Clinical Manifestations of Hemochromatosis in HFE C282Y Homozygotes Identified by Screening by Gordon D McLaren, Christine E McLaren, Paul C Adams, James C Barton, David M Reboussin, Victor R Gordeuk, Ronald T Acton, Emily L Harris, Mark R Speechley, Phyliss Sholinsky, Fitzroy W Dawkins, Beverly M Snively, Thomas M Vogt, John H Eckfeldt, for the Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators

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The WHO’s 75th anniversary: WHO at a pivotal moment in history by Lawrence O Gostin, Roojin Habibi, Benjamin Mason Meier, Helen Clark, K Srinath Reddy, Jemilah Mahmood, Danwood Mzikenge Chirwa, Björn Kümmel, Winnie Mpanju-Shumbusho, Attiya Waris, Miriam K Were

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Career Perspectives for Pediatric Orthopaedic Trainees and Early Practitioners: A Panel Discussion by Jeffrey B. Peck, MD, William Cutchen, MD, Lee Haruno, MPH, Dustin Greenhill, MD, Karen Bovid, MD, Brandon Ramo, MD

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Exploring vestibular stimulation to reduce the influence of cybersickness on virtual reality experiences by Shamus P. Smith, Eugene Nalivaiko, Sam Owen, Didier Depireux, Mark Flynn

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Recent Tectonic Deformation of the Lunar Farside Mare and South Pole–Aitken Basin by C. A. Nypaver, T. R. Watters, J. D. Clark

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Vocational Bias: A Potential Pitfall in the Use of Key Informant Interviews in Pediatric Community Needs Assessments by Kimberly Northrip, Candice Chen, Jennifer Marsh

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On the current and future potential of simulations based on directed acyclic graphs by Lutz P. Breitling, Anca D. Dragomir, Chongyang Duan, George Luta

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Vaccines in the fight against antimicrobial resistance – perspectives from South Africa by A Brink, A Kgasi, A Musyoki, B Kagina, C Feldman, D Reddy, E du Toit, E Kalanxhi, J Meyer, I Impalli, M Schönfeldt, M Sibanda, N Schellack, P Skosana, S Essack, S Dlamini, Y Ramsamy

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Pregnancy and Lifestyle: Short- and Long-Term Effects on Mother's and Her Children's Health by Riitta Luoto, Michelle F. Mottola, Leena Hilakivi-Clarke

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Pediatric Nephrology: Highlights for the General Practitioner by Mouin Seikaly, Sabeen Habib, Amin J. Barakat, Jyothsna Gattineni, Raymond Quigley, Dev Desi

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On convergence of (μ,ν)-sequences of unisolvent rational approximants to meromorphic functions in Cn by C. H. Lutterodt

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Innovative use of space-based technologies to address climate change and related global health crises by Farhan M. Asrar, Helena J. Chapman

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Live or Die: Choice Mechanisms in Stressed Cells by Francesco Cecconi, Laura Soucek, Dennis D. Taub, Elio Ziparo

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State of the Science: Biologically Based Modeling in Risk Assessment by Jane C. Caldwell, Kannan Krishnan, Marina V. Evans

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HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique by Nalia Ismael, Cidia Hussein, Cacildo Magul, Humberto Inguane, Aleny Couto, Amancio Nhangave, Ana Muteerwa, Mahoudo Bonou, Artur Ramos, Peter Wesley Young, Sonia Chilundo, Rhoderick Machekano, Lauren Greenberg, Juliana da Silva, Nilesh Bhatt

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Investigation of Static Performances of 1.2kV 4H-SiC MOSFETs Fabricated Using All ‘Room Temperature’ Ion Implantations by Stephen A. Mancini, Seung Yup Jang, Zeyu Chen, Dongyoung Kim, Alex Bialy, Balaji Raghotamacher, Michael Dudley, Nadeemullah Mahadik, Robert Stahlbush, Mowafak Al-Jassim, Woongje Sung

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Impacts of unilateral U.S. carbon policies on agricultural sector greenhouse gas emissions and commodity markets by Marcel Adenauer, Michael K Adjemian, Shawn Arita, Wade Brorsen, Joseph Cooper, Gyuhyeong Goh, Berna Karali, Mindy Lyn Mallory, Wyatt Thompson, Jisang Yu

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