Positive selection analyses identify a single WWE domain residue that shapes ZAP into a more potent restriction factor against alphaviruses. by Serina Huang, Juliana Girdner, LeAnn P Nguyen, Carina Sandoval, Oliver I Fregoso, David Enard, Melody M H Li

“…In summary, the second WWE domain is critical for engineering a more potent ZAP and fluctuations in PAR binding modulate ZAP antiviral activity. …”
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Comparison of offspring outcomes in women with and without epilepsy by Huali Luo, Xiaomin Mao, Shuli Zhu, Qiong Luo, Jiajia Fang, Qiwei Li

“…Abstract Objective The potential impact of antiseizure medications (ASMs) on abortion rate and bone metabolism in the offspring of pregnant women with epilepsy (WWE) is currently unknown. This research aimed to assess the potential risk by conducting a comparative analysis of bone metabolism‐related indicators in the offspring of WWE. …”
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What do women with epilepsy know about pregnancy? by Miyalani G. Baloyi, Rethabile Khalema, Sumaiya Adam

“…Background: Understanding the intersection of epilepsy and pregnancy, including knowledge gaps and healthcare access for women with epilepsy (WWE), is critical. This study evaluated WWE knowledge gaps and information needs concerning epilepsy’s impact on their sexual and reproductive health during pregnancy and examined healthcare system factors affecting their access to information, aiming to identify areas for improvement in educational and healthcare strategies to enhance health management for WWE. …”
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Barriers to Routine Gynecological Care in Young Adult Females in the United States by Anne M. Clark, Mireya C. Long, Brianna M. Magnusson

“…Those who had delayed WWE expressed higher practical, procedural, and provider barriers compared with those with on-time exams. …”
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Development and internal validation of a prognostic model for predicting tonic-clonic seizures during pregnancy in women with epilepsy by Yanru Du, Wenting Huang, Ying Wang, Jiahe Lin, Niange Xia, Zhenguo Zhu, Xinshi Wang, Yuchen Xu, Huiqin Xu

“…Abstract Background We aim to develop a model to predict the probability of tonic-clonic seizures in women with epilepsy (WWE) at any point during pregnancy until six weeks postpartum. …”
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The use of newer anti-seizure medicines in women with epilepsy in pregnancy: A case series by Joan E. Devin, Fergal O’Shaughnessy, Muskan Sardana, Brian J. Cleary, Jennifer C. Donnelly, Nicola Maher

“…We aimed to describe the use of newer ASMs in women with epilepsy (WWE) attending the Rotunda Hospital, Dublin, in pregnancy, between 2018 and 2023. …”
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Child Development after Fetal Exposure to AED by J Gordon Millichap

“…Researchers at the University of Liverpool and the Department of Neurology, Royal Group of Hospitals, Belfast, UK, investigated the early cognitive development of 155 children born to women with epilepsy (WWE) and exposed in utero to the antiepileptic drug, levetiracetam (LEV) or sodium valproate (VPA).…”
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Criminal Justice in Italy between the End of the Liberal State and Fascism: Transnational Perspectives between the USA and Italy (1919-1945) by Luigi Lacchè

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Meta-analysis of risk factors for pulmonary infection after radical gastrectomy for gastric cancer by Zeng-Li CHEN, Yun-Lan JIANG, Han-Mei PENG, Hong-Mei XIE, Lu LIU, Jie LI

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Then, Now, Forever: Television Wrestling, Seriality, and the Rise of the Cinematic Match during COVID-19 by Oliver Kroener

“…Through a close textual analysis of wrestling programs that were produced without a live crowd during the COVID-19 crisis (e.g., WWE Friday Night Smackdown, Wrestlemania 36), this article examines how television wrestling—in an effort to appeal to its audience—produced a number of cinematic matches that combine distinct elements (e.g., editing, cinematography, sound) of genre filmmaking (e.g., horror, action) with the spectacular athleticism of pro wrestling.…”
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Carbohydrate utilization by the gut microbiome determines host health responsiveness to whole grain type and processing methods by Caroline Smith, Mallory J. Van Haute, Yibo Xian, Rafael R. Segura Munoz, Sujun Liu, Robert J. Schmaltz, Amanda E. Ramer-Tait, Devin J. Rose

“…Our work demonstrates that a greater understanding of food processing effects on the microbiome is necessary for developing foods that promote rather than diminish host health.Abbreviations: CU- carbohydrate utilization; SCFA- short-chain fatty acids; GF- germ-free; HMA, human-microbiome associated; ipGTT- intraperitoneal glucose tolerance test; HOMA-IR- Homeostatic Model Assessment for Insulin Resistance; AUC- area under the glycemia curve; ASV- amplicon sequence variant; lf- low-fat; wd- Western diet; wd_wwp- Western diet containing whole wheat porridge; wd_wwe- Western diet containing whole wheat extrudate; wd_bre- Western diet containing brown rice extrudate; wd_extr- Western diet containing either whole wheat or brown rice extrudate.…”
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Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation by Chengyu Shi, Ying Wang, Minjie Wu, Yu Chen, Fangzhou Liu, Zheyuan Shen, Yiran Wang, Shaofang Xie, Yingying Shen, Lingjie Sang, Zhen Zhang, Zerui Gao, Luojia Yang, Lei Qu, Zuozhen Yang, Xinyu He, Yu Guo, Chenghao Pan, Jinxin Che, Huaiqiang Ju, Jian Liu, Zhijian Cai, Qingfeng Yan, Luyang Yu, Liangjing Wang, Xiaowu Dong, Pinglong Xu, Jianzhong Shao, Yang Liu, Xu Li, Wenqi Wang, Ruhong Zhou, Tianhua Zhou, Aifu Lin

“…Mechanistically, TMUB1 competes with HECT, UBA and WWE domain-containing protein 1 (HUWE1), a E3 ubiquitin ligase, to interact with PD-L1 and inhibit its polyubiquitination at K281 in the endoplasmic reticulum. …”
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