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  1. 5241

    Pharmacological insights and therapeutic advances of mangiferin against various pathological conditions in liver diseases by Tanvir Zaman Shoyshob, Sumaya Akter, Muhammad Ramiz Uddin, Mithila Farjana, Akhi Moni, Wonhyo Seo, Md. Golzar Hossain, Md Jamal Uddin

    Published 2025-03-01
    “…Currently, liver diseases have become a serious global health issue, and this situation occurs due to the exposure of the liver to different agents, such as chemicals, alcohol, viruses, and autoimmune diseases. Mangiferin is a natural bioactive xanthone C-glycoside compound and a potent antioxidant that is widely found in medicinal plants such as the leaves of Mangifera indica L. …”
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  2. 5242

    Molecular Characterization and Evolution Analysis of Two Forms of TLR5 and TLR13 Genes Base on Larimichthys crocea Genome Data by Lihua Jiang, Liyi Pei, Ping Wang, Liqin Liu, Gong Li, Binjian Liu, Zhenming Lǚ, Tabata Hiromasa, Hao Pan, Atsushi Ogura

    Published 2020-01-01
    “…TLR13 is a TLR that localizes to endosomes and recognizes nucleic acids released by internal microorganisms, including viruses, bacteria, and fungi. Here, the full-length coding sequence (CDS), protein structure, and immune response and subcellular localization of TLR5 (TLR5S) and TLR13 were characterized in large yellow croaker (Larimichthys crocea). …”
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  3. 5243

    Novel adaptive immune systems in pristine Antarctic soils by Marc W. Van Goethem, Oliver K. I. Bezuidt, Rian Pierneef, Surendra Vikram, David W. Hopkins, Thomas Aspray, Grant Hall, Stephan Woodborne, Ian D. Hogg, Trent R. Northen, Weidong Kong, Daniele Daffonchio, Don A. Cowan, Yves Van de Peer, Manuel Delgado-Baquerizo, Thulani P. Makhalanyane

    Published 2025-01-01
    “…Although several studies have investigated the phylogenetic repertoire of bacteria and viruses in these poly-extreme environments with freezing temperatures, high ultra violet irradiation levels, low moisture availability and hyper-oligotrophy, the evolutionary mechanisms governing microbial immunity remain poorly understood. …”
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  4. 5244

    Characterization of acute respiratory infections behavior. Cienfuegos Province. First quarter 2020 by Bárbara del Rosario Téllez Cacín, María Lina Valdés Gómez, José Aurelio Díaz Quiñones, Lourdes Elena Duany Badell, Ling Denisse Santeiro Pérez, Sadys Suarez del Villar Seuret

    Published 2020-10-01
    “…<br /><strong>Results:</strong> the characterizing essentialities were: its highest incidence in children under five years of age and adults 60 years and over; the leading cause of death was from community-acquired pneumonia; the identified circulating viruses were respiratory syncytial, parainfluenza, unsubtyped influenza A, and coronavirus. …”
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  5. 5245

    Antibacterial Activity of Rationally Designed Antimicrobial Peptides by Marius B. Tincho, Thureyah Morris, Mervin Meyer, Ashley Pretorius

    Published 2020-01-01
    “…Antimicrobial Peptides (AMPs) are components of the first line of defense for prokaryotes and eukaryotes and have a wide range of activities against Gram-negative and Gram-positive bacteria, fungi, cancer cells, and protozoa, as well as viruses. In this study, peptides which were initially identified for their HIV inhibitory activity were further screened for antibacterial activity through determination of their kinetics as well as their cytotoxicity. …”
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  6. 5246

    A rapid visual detection method for porcine teschovirus through reverse transcription recombinase-aided amplification coupled with lateral flow dipstick by Qiu-Yong Chen, Zhi-Hua Sun, Ru-Jing Chen, Xue-Min Wu, Yong-Liang Che, Ren-Jie Wu, Jing-Li Qiu, Bing He, Long-Bai Wang, Lun-Jiang Zhou

    Published 2024-12-01
    “…Meanwhile, the assay established in this study showed no interaction with other associated diarrhea viruses, and has high specificity to PTV, with a minimal detection limit of 10 copies/μL and good repeatability. 128 clinical samples suspected of having a PTV infection were tested by RT-PCR and RT-RAA-LFD, respectively. …”
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  7. 5247

    Real-World Effectiveness of Portable Air Cleaners in Reducing Home Particulate Matter Concentrations by Frederic T. Lu, Robert J. Laumbach, Alicia Legard, Nirmala T. Myers, Kathleen G. Black, Pamela Ohman-Strickland, Shahnaz Alimokhtari, Adriana de Resende, Leonardo Calderón, Gediminas Mainelis, Howard M. Kipen

    Published 2023-11-01
    “…Abstract Portable air cleaners (PACs) equipped with HEPA filters are gaining attention as cost-effective means of decreasing indoor particulate matter (PM) air pollutants and airborne viruses. However, the performance of PACs in naturalistic settings and spaces beyond the room containing the PAC is not well characterized. …”
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  8. 5248

    NRF2 Antioxidant Response and Interferon‐Stimulated Genes Are Differentially Expressed in SARS‐CoV‐2‐Positive Young Subjects by Walter Toscanelli, Matteo Fracella, Marta De Angelis, Carolina Scagnolari, Leonardo Sorrentino, Elena Piselli, Maria Elena Marcocci, Fabio Midulla, Enrica Mancino, Raffaella Nenna, Laura Petrarca, Anna Teresa Palamara, Guido Antonelli, Alessandra Pierangeli, Lucia Nencioni

    Published 2025-01-01
    “…ABSTRACT Background Several respiratory viruses, including Severe Acute Respiratory Syndrome‐Coronavirus‐2 (SARS‐CoV‐2), suppress nuclear factor‐E2‐related factor‐2 (NRF2) antioxidant response, generating oxidative stress conditions to its advantage. …”
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  9. 5249

    Fungi in the Gut Microbiota: Interactions, Homeostasis, and Host Physiology by Hao-Yu Liu, Shicheng Li, Kennedy Jerry Ogamune, Abdelkareem A. Ahmed, In Ho Kim, Yunzeng Zhang, Demin Cai

    Published 2025-01-01
    “…The mammalian gastrointestinal tract is a stage for dynamic inter-kingdom interactions among bacteria, fungi, viruses, and protozoa, which collectively shape the gut micro-ecology and influence host physiology. …”
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  10. 5250

    Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings by Shyam Kumar Mishra, Tanzina Akter, Umme Laila Urmi, George Enninful, Manjulatha Sara, Jiawei Shen, Dittu Suresh, Liangjun Zheng, Elias Shiferaw Mekonen, Binod Rayamajhee, Francesco M. Labricciosa, Massimo Sartelli, Mark Willcox

    Published 2025-01-01
    “…We explore the mechanism of action of AMPs against bacteria, viruses, fungi and parasites. While these peptides hold significant promise, their application in mainstream drug development is hindered by challenges such as low bioavailability and potential toxicity. …”
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  11. 5251

    Microbial biopesticides: A one health perspective on benefits and risks by Panqin Cai, George Dimopoulos

    Published 2025-06-01
    “…Microbial biopesticides, derived from bacteria, viruses, fungi, protozoa, or nematodes, offer potentially significant benefits for promoting One Health and contributing to several United Nations Sustainable Development Goals (SDGs). …”
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  12. 5252

    Simple and Fail-safe Method to Transform Miniprep Escherichia coli Strain K12 Plasmid DNA Into Viable Agrobacterium tumefaciens EHA105 Cells for Plant Genetic Transformation by Beenzu Siamalube, Emmanuel Ehinmitan, Maina Ngotho, Justus Onguso, Steven Runo

    Published 2025-01-01
    “…Conventionally, plant genetic transformation has relied on time-consuming, costly, and technically demanding procedures, such as electroporation and chimeric viruses or biolistic methods, which usually yield variable transformation efficiencies. …”
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  13. 5253

    Conducting polymer-based electrochemical sensors: Progress, challenges, and future perspectives by Aashutosh Dube, Shweta J. Malode, Abdullah N. Alodhayb, Kunal Mondal, Nagaraj P. Shetti

    Published 2025-08-01
    “…Conducting polymers and their nanocomposites-based electrochemical sensors have demonstrated exceptional capabilities towards detecting various biomolecules, heavy metals, pesticides, and viruses like SARS-COV-2. Incorporation of redox mediators, use of conducting hydrogels, and molecular imprinting are promising strategies for better performance of the derived sensor. …”
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  14. 5254

    Plant Mediated Green Synthesis and Antiviral Activity of Gold and Copper Nanoparticles using Malva parviflora L. Leaf Extract by Seyedeh Raana Charghani, Saadat Rastegarzadeh, Parzhak Zoufan, Seyedeh Elham Rezatofighi

    Published 2024-06-01
    “…Although CuNPs have more cytotoxicity than AuNPs, they are more effective at killing viruses. Additionally, ethanolic extract showed significant antiviral activity at non-cytotoxic concentrations.…”
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  15. 5255

    Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features by Yao Liu, Bohan Yang, Qi Qi, Shijie Liu, Yiheng Du, Linlin Ye, Qiong Zhou

    Published 2025-01-01
    “…However, in the detection of CMV/EBV viruses, there was no significant difference between the detection rate of mNGS and that of viral DNA quantification (p = 1.000 and 0.152). mNGS analysis revealed Prevotella, Streptococcus, Veillonella, Rothia, and Capnocytophaga as the most prevalent genera in the LRT of lung cancer patients. …”
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  16. 5256

    A scoping review on bio-aerosols in healthcare and the dental environment. by Charifa Zemouri, Hans de Soet, Wim Crielaard, Alexa Laheij

    Published 2017-01-01
    “…Fifty-five bacterial species, 45 fungi genera and ten viruses were identified in a hospital setting and 16 bacterial and 23 fungal species in the dental environment. …”
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  17. 5257

    GENOME POLITICS: STRATEGY AND TACTICS by Jonas Rubikas

    Published 1999-01-01
    “…This is clearly seen when the comparison between the information content (the gene number) and the life cycle of small genomes (plasmids, viruses, singlecellular prokaryotic organisms) is made: large space is occupied by information on replication enzymes and the sequence of replication origin. …”
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  18. 5258

    Temperate phage-antibiotic synergy is widespread—extending to Pseudomonas—but varies by phage, host strain, and antibiotic pairing by Rabia Fatima, Alexander P. Hynes

    Published 2025-02-01
    “…ABSTRACT Bacteriophages (phages) are bacterial-specific viruses that can be used alone or with antibiotics to reduce bacterial load. …”
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  19. 5259

    Povidone-iodine in ophthalmological practice by I.A. Koroleva, Kozhukhov A.A

    Published 2018-07-01
    “…Antiseptic drugs, in particular different concentrations of povidone-iodine solution, have bactericidal activity with a wide spectrum of action (against bacteria, fungi, viruses, protozoa), lack of resistance to microorganisms, safety and good tolerability in local applications, and economic accessibility. …”
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  20. 5260

    Enhancers and genome conformation provide complex transcriptional control of a herpesviral gene by David W Morgens, Leah Gulyas, Xiaowen Mao, Alejandro Rivera-Madera, Annabelle S Souza, Britt A Glaunsinger

    Published 2024-11-01
    “…Abstract Complex transcriptional control is a conserved feature of both eukaryotes and the viruses that infect them. Despite viral genomes being smaller and more gene dense than their hosts, we generally lack a sense of scope for the features governing the transcriptional output of individual viral genes. …”
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