Immunological Evaluation for Personalized Interventions in Children with Tuberculosis: Should It Be Routinely Performed? by Laura E. Carreto-Binaghi, Esmeralda Juárez, Silvia Guzmán-Beltrán, María Teresa Herrera, Martha Torres, Alejandro Alejandre, José Arturo Martínez-Orozco, Eduardo Becerril-Vargas, Yolanda Gonzalez

“…Here, we describe the immunological evaluation of eight pediatric patients infected with a member of the M. tuberculosis complex, most of them with concomitant pulmonary infections (bacteria, viruses, or fungi). We assessed the functionality of several innate immunity receptors, IL-12 receptor, and IFN-γ receptor, as well as the antioxidant levels (glutathione), which are essential mechanisms for fighting intracellular pathogens such as M. tuberculosis. …”
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Exploring Immune Responses through Dynamic Modeling of Cell-Immune Interactions in Viral Infection and Vaccination by Kwang Su Kim, Il Hyo Jung, Jong Hyuk Byun

“…Through a mathematical model, we explore the intricate interactions between host cells and viruses to assess the impact of vaccination on viral replication. …”
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An Overview of the Skin Microbiome, the Potential for Pathogen Shift, and Dysbiosis in Common Skin Pathologies by Anita Smith, Roberta Dumbrava, Noor-Ul-Huda Ghori, Rachael Foster, James Campbell, Andrew Duthie, Gerard Hoyne, Marius Rademaker, Asha C. Bowen

“…Recent interest in the diverse ecosystem of bacteria, fungi, parasites, and viruses that make up the skin microbiome has led to several studies investigating the microbiome in healthy skin and in a variety of dermatological conditions. …”
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Base Composition Characteristics of Mammalian miRNAs by Bin Wang

“…Endogenous miRNAs have been found in various organisms, including animals, plants, and viruses. Mammalian miRNAs are evolutionarily conserved, are scattered throughout chromosomes, and play an important role in the immune response and the onset of cancer. …”
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Features of Human Herpesvirus-6A and -6B Entry by Takahiro Maeki, Yasuko Mori

“…The process of herpesvirus entry into target cells is complicated, and in the case of HHV-6A and HHV-6B, the detailed mechanism remains to be elucidated, although both viruses are known to enter cells via endocytosis. …”
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Role of phage therapy in acute gastroenteritis by Somaieh Sabzali, Setareh Pazhouhnia, Kiana Shahzamani, Peyman Adibi Sedeh

“…This complex ecosystem involves a diverse array of microorganisms such as viruses, fungi, and bacteria, collectively known as the gut microbiota. …”
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A Method of Intrusion Detection Based on WOA-XGBoost Algorithm by Yan Song, Haowei Li, Panfeng Xu, Dan Liu

“…With the development of information technology, computer networks have become a part of people’s lives and work. However, computer viruses and malicious network attacks make network security face huge challenges, and more accurate detection of attacks has become the focus of attention to current computer fields. …”
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The effect of using Naive Bayes to detect spam email by Sun Zehui

“…However, it has also become a channel for spreading undesirable information, such as content from hackers, viruses, violence, pornography, and superstition. …”
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Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions by Nadia Martinez-Martin

“…This review discusses available technologies for the high throughput study of extracellular protein interactions between pathogens and their hosts, with a focus on mammalian viruses and bacteria. Emerging work illustrates a rich landscape for extracellular host-pathogen interaction and points towards the evolution of multifunctional pathogen-encoded proteins. …”
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Covid-19 and the Call to Sanitize Human Conscience by Prem Xalxo SJ

“…Apart from highlighting danger of dominant technocratic paradigm, the pandemic has also called for the sanitization of our conscience and unmask oneself to let the viruses of egocentric attitude, narcissism, greed, pride and unquenchable thirst for more and better which ultimately leads to the unbridled exploitation of the natural resources. …”
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Research on security of mobile payment for commercial bank by Xi CHEN, You-liang TIAN, Zhuo MA, Jian-feng MA

“…There is no doubt that mobile payment is the spotlight in Internet finance now.Although users can enjoy quick and convenient services,they have to face with more severe security problems at the same time:the attack incidents,such as cellphone Trojan and privacy leaks emerge endlessly.Lots of viruses which are designed for attacking financial payments can steal users’ personal information including account,password and verification code in the proceedings of remote payment and near field communication.Security issues have already seriously impeded the further development of the mobile payment market.To solve the above problems,discusses the security issues in mobile terminals,payments,network and interactive logic of banking business from financial institutions’ perspective was discussed systematically.In addition,current status of relevant security key technologies are summarized from academic research community and industry fields.Finally,based on related research achievements,the design of system architecture and suggestions for mobile payment security are proposed,which can guide the future development of commercial bank.…”
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Phage Therapy -- Everything Old Is New again by Andrew M Kropinski

“…The study of bacterial viruses (bacteriophages or phages) proved pivotal in the nascence of the disciplines of molecular biology and microbial genetics, providing important information on the central processes of the bacterial cell (DNA replication, transcription and translation) and on how DNA can be transferred from one cell to another. …”
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Potentiating intratumoral therapy with immune checkpoint inhibitors: shifting the paradigm of multimodality therapeutics by B.E. Nelson, A. Naing, S. Fu, R.A. Sheth, R. Murthy, S. Piha-Paul

“…Notable IT approaches include oncolytic viruses, toll-like receptor agonists, and stimulator of interferon gene agonists with ICIs. …”
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Beta-Defensin-2 and Beta-Defensin-3 Reduce Intestinal Damage Caused by Salmonella typhimurium Modulating the Expression of Cytokines and Enhancing the Probiotic Activity of Enteroc... by Alessandra Fusco, Vittoria Savio, Marcella Cammarota, Alberto Alfano, Chiara Schiraldi, Giovanna Donnarumma

“…If this healthy microbiota is disrupted by antibiotics, chemotherapy, or a change in diet, intestinal colonization by pathogenic bacteria or viruses may occur, leading to disease. To manage substantial microbial exposure, epithelial surfaces of the intestinal tract produce a diverse arsenal of antimicrobial peptides (AMPs), including, of considerable importance, the β-defensins, which directly kill or inhibit the growth of microorganisms. …”
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A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA by Man Lu, Zhiqiang Cao, Luoan Xiong, Hongying Deng, Kangkang Ma, Ning Liu, Yanding Qin, Shen-Bo Chen, Jun-Hu Chen, Yao Li, Yijin Liu, Zhongbo Yu

“…Our understanding of the RNA catalytic mechanism will be beneficial for ribozyme’s biotechnological applications and as potential therapeutics against RNA viruses.…”
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Fire Ants (Solenopsis spp.) and Their Natural Enemies in Southern South America by Juan Briano, Luis Calcaterra, Laura Varone

“…Ecological and biological information is reported on local fire ants and their microsporidia, nematodes, viruses, phorid flies, eucharitid wasps, strepsiptera, and parasitic ants. …”
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Targeted therapeutic strategies for Nectin-4 in breast cancer: Recent advances and future prospects by Yufei Wang, Guangliang Li, Hanying Wang, Quan Qi, Xian Wang, Haiqi Lu

“…Nectin-4-targeted approaches, such as ADCs, oncolytic viruses, photothermal therapy and immunotherapy, have shown promising results in early-phase clinical trials. …”
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Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases by Weiwei Zhang, Feiqi Zhu, Jie Zhu, Kangding Liu

“…Phospholipase D (PLD) is an enzyme that consists of six isoforms (PLD1–PLD6) and has been discovered in different organisms including bacteria, viruses, plants, and mammals. PLD is involved in regulating a wide range of nerve cells’ physiological processes, such as cytoskeleton modulation, proliferation/growth, vesicle trafficking, morphogenesis, and development. …”
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Far beyond Phagocytosis: Phagocyte-Derived Extracellular Traps Act Efficiently against Protozoan Parasites In Vitro and In Vivo by Liliana M. R. Silva, Tamara Muñoz-Caro, Rafael A. Burgos, Maria A. Hidalgo, Anja Taubert, Carlos Hermosilla

“…Recent investigations showed evidence that ETosis is a widely spread effector mechanism in vertebrates and invertebrates being utilized to entrap and kill bacteria, fungi, viruses, and protozoan parasites. ETs are released in response to intact protozoan parasites or to parasite-specific antigens in a controlled cell death process. …”
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Engineering CRISPR for emerging therapeutic applications by Xiaoqi Sun, Zhuang Liu

“…Clustered regularly interspaced short palindromic repeats (CRISPRs) were originally identified in bacterial and archaeal genomes as an adaptive immune response against invading viruses and phages. The discovery of the ability of CRISPR–Cas9 to cut targeted DNA sequences at predetermined sites has introduced a new era of precision and flexibility in genome editing. …”
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