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4841
Assessment of psychological health effects of nurses during 2022–2023 of the COVID-19 pandemic: a descriptive study in Southern Taiwan
Published 2025-12-01“…Background Nurses on the frontlines of the pandemic have increased workloads, burnout, and virus exposure, leading to mental health challenges and a lack of resources for patient care. …”
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4842
Leupaxin promotes hepatic gluconeogenesis and glucose metabolism by coactivation with hepatic nuclear factor 4α
Published 2025-01-01“…We further leveraged cell cultures and mouse models to validate the functional importance of molecular pathway during gluconeogenesis by using adenovirus-mediated overexpression and adeno-associated virus shRNA–mediated knockdown both in vivo and ex vivo, such as in ob/db/DIO mice, HepG2 and primary hepatocytes. …”
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4843
Identification of EXPA4 as a key gene in cotton salt stress adaptation through transcriptomic and coexpression network analysis of root tip protoplasts
Published 2025-01-01“…Silencing of the GaEXPA4 gene through virus-induced gene silencing heightened cotton’s sensitivity to salt stress, leading to increased wilting, elevated lipid peroxidation, and impaired antioxidant activity under salt conditions compared to controls. …”
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4844
Characterization of the gut microbiota and systemic inflammation in HIV-exposed uninfected infants from a resource-limited setting at 6 weeks of age
Published 2024-11-01“…Objective: Infants born to mothers infected with human immunodeficiency virus (HIV) experience heightened morbidity and mortality, likely due to systemic immune dysregulation potentially linked to gut microbial dysbiosis. …”
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4845
The immune landscape and viral shedding of Omicron SARS-CoV-2 variants implicate immune escape
Published 2025-01-01“…BackgroundThree years into the SARS-CoV-2 pandemic, the virus continues to mutate despite widespread vaccination, posing ongoing challenges for epidemic prevention and control. …”
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4846
Black carp RNF115 restricts IRF3/7-mediated antiviral signaling in innate immunity
Published 2025-01-01“…Immunofluorescence assays revealed the cytoplasmic and nuclear distribution of RNF115 in the presence or absence of spring viremia of carp virus (SVCV) infection. Overexpression of RNF115 impaired interferon (IFN) and the related interferon-stimulated gene (ISG) mRNA expression, while upregulating SVCV replication. …”
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4847
The potential mechanism of Isodon suzhouensis against COVID-19 via EGFR/TLR4 pathways
Published 2024-11-01“…Corona Virus Disease 2019 (COVID-19) has brought the new challenges to scientific research. …”
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4848
Performance of antiretroviral drugs supply chain management and related challenges in Amhara National Regional State, Ethiopia. In the case of public health facilities found in the...
Published 2025-03-01“…Background: Effective human immunodeficiency virus (HIV) treatment depends on uninterrupted delivery of prescribed antiretroviral (ARV) drug regimens at anti-retroviral therapy (ART) sites. …”
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4849
Pre-exposure Prophylaxis Awareness and Endorsement among Adolescents and Young Adults in Tanzania: Insights from the 2022 Demographic and Health Survey
Published 2025-01-01“…Background: Pre-exposure prophylaxis (PrEP) is an effective measure for preventing human immunodeficiency virus (HIV) infection among people at risk, including adolescents and young adults (AYA). …”
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4850
Lack of activity of HIV-1 integrase strand-transfer inhibitors on recombinase activating gene (RAG) activity at clinically relevant concentrations
Published 2025-01-01“…ABSTRACT Human immunodeficiency virus 1 (HIV-1) infection remains a global health concern, with nearly 30 million people on antiretroviral (ARV) treatment. …”
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4851
Association of HIVEP3 Gene and Lnc RNA with Femoral Neck Bone Mineral Content and Hip Geometry by Genome-Wide Association Analysis in Chinese People
Published 2020-01-01“…We found that one SNP rs35282355 located in the human immunodeficiency virus type 1 enhancer-binding protein 3 gene (HIVEP3) and another 25 SNPs located in LINC RNA were significantly correlated with bone mineral content (BMC) in the femoral neck (P= 2.30 × 10−9, P < 5 × 10−8). …”
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4852
Посттрансплантаційний лімфопроліферативний розлад у дитини після трансплантації нирки: клінічний випадок...
Published 2024-05-01“…Тригером розвитку PTLD може бути активна реплікація Епштейна-Барра вірусу (Epstein-Barr virus, EBV), а також інші фактори ризику. Цей розлад становить спектр клінічних захворювань, від доброякісного захворювання, подібного до мононуклеозу, до фульмінантної лімфоми. …”
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4853
Global temporal trends and projections of hepatitis B-related cirrhosis among adolescents and young adults from 1990 to 2035: an analysis based on the global burden of disease stud...
Published 2025-01-01“…Few studies have explored the disease burden and mortality trend of cirrhosis caused by hepatitis B virus infection among adolescents and young adults (AYAs, aged 15–39 years). …”
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4854
Rapid aging of influenza epidemics in China from 2005/06 to 2016/17: A population-based study
Published 2025-06-01“…Methods: We collected weekly influenza surveillance data from 2005/06 to 2016/17, and quantified the aging of influenza-like illness (ILI) and influenza virus-positive cases in China via the mean age of the influenza cases and the proportion of individuals aged 65 and above among the influenza cases. …”
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4855
Genome-wide association mapping of biochemical traits and its correlation with MYMIV resistance in mungbean (Vigna radiata L. Wilczek)
Published 2024-12-01“…Abstract The mungbean yellow mosaic India virus (MYMIV, Begomovirus vignaradiataindiaense) causes Yellow Mosaic Disease (YMD) in mungbean (Vigna radiata L.). …”
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4856
The prevalence of thromboembolic events among COVID-19 patients admitted to a single centre intensive care unit (ICU): an epidemiological study from a Malaysian population
Published 2025-12-01“…The proportions of patients with TE events who died, and factors associated with TE events were explored.Methods In this retrospective cohort study, patients with PCR confirmed SARS-CoV-2 virus and who received thromboprophylaxis within February 2020–2021 were included. …”
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4857
Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan
Published 2024-09-01“…BackgroundAs the life expectancy of people living with human immunodeficiency virus (HIV) (PLWH) has improved, chronic disease burden and polypharmacy have increased in PLWH. …”
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4858
B7-H3 CAR-T cell therapy combined with irradiation is effective in targeting bulk and radiation-resistant chordoma cancer cells
Published 2025-01-01“…Retroviral particles containing either B7-H3 or CD19 CAR-expressing virus were transduced into T cells derived from peripheral blood mononuclear cells isolated from healthy human donor blood to prepare CAR-T cells. …”
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4859
A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis
Published 2025-02-01“…Abstract Background/Aim To investigate the prognostic value of circulating apolipoprotein AI (apoAI) levels and develop a new prognostic model in individuals with acute-on-chronic liver failure (ACLF) and acute decompensation (AD) of liver cirrhosis caused by hepatitis B virus (HBV) infection. Methods Baseline levels of serum lipids were measured, and data concerning the presence of complications were collected from 561 HBV-ACLF and AD patients. …”
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4860
Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV...
Published 2022-01-01“…Background. Hepatitis B virus (HBV) is the leading cause of liver-related diseases. …”
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