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4221
Generation of Mature Nα-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α
Published 2013-01-01“…Nα-terminal acetylated thymosin α1 (Tα1), a 28-amino-acid peptide, is an immune modifier that has been used in the clinic to treat hepatitis B and C virus (HBV/HCV) infections. We previously documented Nα-terminal acetylation of recombinant prothymosin α (ProTα) in E. coli. …”
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4222
Research on blood donation and supply of red blood cell products to medical institutions under the spread of COVID-19 disease in Japan
Published 2025-01-01“…Due to the spread of SARS-CoV-2 virus infectious disease (COVID-19), blood donation events had to be cancelled, and there were concerns about a decrease in the number of blood donors from late February 2020 in Japan. …”
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4223
Retrospective analysis of enzootic bovine leucosis spread in Republic of Dagestan considering natural and climatic conditions
Published 2023-12-01“…From 1988 to 2022, the Republican veterinary laboratories serologically tested3,205,118 animal sera for the antibodies to bovine leukaemia virus (BLV) antigen, and 76,133 (2.4%) of them were positive. …”
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4224
Enzymatic synthesis of reactive RNA probes containing squaramate-linked cytidine or adenosine for bioconjugations and cross-linking with lysine-containing peptides and proteins
Published 2025-01-01“…Inhibition of RNA-depending RNA polymerases from Japanese Encephalitis virus was observed through formation of covalent cross-link which was partially identified by MS/MS analysis. …”
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4225
Sensitivity and identifiability analysis of COVID-19 pandemic models
Published 2021-03-01“…The performed analysis has demonstrated that the virus contagiousness is identif iable from the number of daily conf irmed, critical and recovery cases. …”
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4226
Value judgment of life quality of women diagnosed with HIV/AIDS in Maceio, Alagoas, Brazil
Published 2014-10-01“…The risk of contamination by HIV virus has been increasing between heterosexual partners, affecting mainly poor women from rural areas. …”
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4227
Case Report of HIV and Neurosyphilis Coinfection in a Recent Migrant: Old Diseases in New Faces
Published 2024-11-01“…Introduction: Coinfection with human immunodeficiency virus (HIV) and Treponema pallidum represents a unique challenge in management, with increased risk of neurological complications. …”
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4228
Visualization of Observational Learning and Peer Influence on Plastic Waste Diversity in the Campus Environment Using ArcGIS
Published 2024-07-01“…Indeed, certain relationships and interactions related to the disposal of waste into the natural environment instead of proper waste collection points have spread like a virus and led to the formation of behavioral patterns. …”
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4229
Comparison of reverse-transcriptase polymerase chain reaction (rt-pcr) and rapid test for the detection of bovine rotavirus and bovine coronavirus in anatolian water
Published 2020-10-01“…When compared with RT-PCR results for both viruses, the rapid test sensitivity and specificity was determined as 0% and 100%, respectively. …”
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4230
A Dual-Type L2 11-88 Peptide from HPV Types 16/18 Formulated in Montanide ISA 720 Induced Strong and Balanced Th1/Th2 Immune Responses, Associated with High Titers of Broad Spectru...
Published 2018-01-01“…E. coli-derived concatenated, multitype L2-conserved epitopes of human papillomavirus (HPV) L2 protein might represent a less expensive and pan-type vaccine alternative (compared to type-specific HPV L1 virus-like particles), if stable protein expression and strong immunogenicity features could be met. …”
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4231
DLCDroid an android apps analysis framework to analyse the dynamically loaded code
Published 2025-01-01“…We evaluate DLCDroid’s performance using a dataset comprising real-world benign and malware apps from reputed repositories like VirusShare and the Google Play Store. Compared to state-of-the-art approaches, the results indicate a significant improvement in detecting sensitive information leaks, more than 95.6% caused by reflection API. …”
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4232
GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression
Published 2024-12-01“…Intra-articular injection of recombinant adeno-associated virus carrying GATD3A significantly alleviates the osteoarthritis phenotype in male mice. …”
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4233
Discovering natural products as potential inhibitors of SARS-CoV-2 spike proteins
Published 2025-01-01“…Abstract The ongoing global pandemic caused by the SARS-CoV-2 virus has demanded the urgent search for effective therapeutic interventions. …”
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4234
Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81
Published 2023-11-01“…They display anticancer and antiviral effects, reducing the entry of hepatitis C virus (HCV) into hepatocarcinoma cells. The large extracellular loop (LEL) of the tetraspanin protein CD81 represents a molecular target for both Hz-A and Hz-B. …”
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4235
The Impact of the COVID-19 Pandemic on the Mental Health of Older Primary Care Patients and Their Family Members
Published 2022-01-01“…The COVID-19 pandemic introduced mandatory stay-at-home orders and concerns about contracting a virus that impacted the physical and mental health of much of the world’s population. …”
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4236
Diagnosis and presenting features of autoimmune hepatitis at a central referral hospital in South Africa
Published 2024-04-01“…Similarly, few studies have focused on the relationship between AIH and Human-Immunodeficiency Virus (HIV) infection. Aim We aim to describe the presenting features of AIH from a single referral centre in a Sub-Sahara African setting. …”
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4237
Impact of Tat Genetic Variation on HIV-1 Disease
Published 2012-01-01“…The human immunodeficiency virus type 1 (HIV-1) promoter or long-terminal repeat (LTR) regulates viral gene expression by interacting with multiple viral and host factors. …”
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4238
Advanced Applications of Fuel Cells during the COVID-19 Pandemic
Published 2021-01-01“…Every day, the number of new patients and the number of deaths are increasing immensely, while specific drugs for this virus are still being developed. Hospitals are struggling to accommodate patients, resulting in a large number of temporary hospitals. …”
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4239
Study of Abiotic and Biotic Parameters Affecting the Abundance of Mosquito Larvae (Diptera: Culicidae) in the Region of Fez (Morocco)
Published 2020-01-01“…Culex pipiens (Linnaeus, 1758), known as the major vector in the transmission of West Nile virus fever (WNV), was the most common species of all mosquito larvae collected. …”
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4240
LINC02282 promotes DNA methylation of TRIM6 by recruiting DNMTs to inhibit the progression of Parkinson's disease
Published 2025-03-01“…In addition, LINC02282 overexpression using an adeno-associated virus reduced neuronal damage in PD mice. LINC02282 was mainly localized in the nucleus, and LINC02282 promoted the methylation of the tripartite motif-containing protein 6 (TRIM6) promoter to inhibit TRIM6 expression. …”
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