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3501
Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme Metabolism
Published 2010-01-01“…Recently, the analysis of mice from which the gene coding for the heme exporter Feline Leukemia Virus subgroup C Receptor (FLVCR1) is deleted suggested that this gene may be involved in the pathogenesis of DBA. …”
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3502
Comprehensive influence evaluation algorithm of complex network nodes based on global-local attributes
Published 2022-09-01“…Mining key nodes in the network plays a great role in the evolution of information dissemination, virus marketing, and public opinion control, etc.The identification of key nodes can effectively help to control network attacks, detect financial risks, suppress the spread of viruses diseases and rumors, and prevent terrorist attacks.In order to break through the limitations of existing node influence assessment methods with high algorithmic complexity and low accuracy, as well as one-sided perspective of assessing the intrinsic action mechanism of evaluation metrics, a comprehensive influence (CI) assessment algorithm for identifying critical nodes was proposed, which simultaneously processes the local and global topology of the network to perform node importance.The global attributes in the algorithm consider the information entropy of neighboring nodes and the shortest distance nodes between nodes to represent the local attributes of nodes, and the weight ratio of global and local attributes was adjusted by a parameter.By using the SIR (susceptible infected recovered) model and Kendall correlation coefficient as evaluation criteria, experimental analysis on real-world networks of different scales shows that the proposed method is superior to some well-known heuristic algorithms such as betweenness centrality (BC), closeness centrality (CC), gravity index centrality(GIC), and global structure model (GSM), and has better ranking monotonicity, more stable metric results, more adaptable to network topologies, and is applicable to most of the real networks with different structure of real networks.…”
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3503
Love Them & Leave Them: science-based rationale for a campaign at the public health-conservation interface
Published 2025-01-01“…., bubonic plague, Ebola, Hendra virus). Public health messaging intended to mitigate these zoonotic disease risks can inadvertently induce fear of wildlife, thereby resulting in wildlife culling and habitat destruction. …”
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3504
Christianity, ‘supernatural’ beliefs and COVID-19
Published 2023-06-01“…Issues around social distancing and lockdown directly impacted articulation and religious expression, while understanding of the pandemic and the virus were mediated through constructions of religio-spiritual beliefs. …”
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3505
Spatial heterogeneity of the hepatocellular carcinoma microenvironment determines the efficacy of immunotherapy
Published 2025-01-01“…In recent years, new immune approaches, including adoptive cell therapy, tumor vaccines, and oncolytic virus therapy, have shown great potential. As the efficacy of immunotherapy mainly depends on the spatial heterogeneity of the tumor immune microenvironment, it is necessary to elucidate the crosstalk between the composition of the liver cancer immune environment, from which potential therapeutic targets can be selected to provide more appropriate individualized treatment programs. …”
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3506
AXL inhibitors selected by molecular docking: Option for reducing SARS-CoV-2 entry into cells
Published 2022-09-01“…A new therapeutic target on the human cellular membrane is AXL (anexelekto), proposed as an independent pathway by which interaction with the S protein of SARS-CoV-2 allows the virus to enter the cell, without the participation of ACE2. …”
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3507
PREVALENCIA SEROLÓGICA DEL SÍNDROME REPRODUCTIVO Y RESPIRATORIO PORCINO (PRRS) EN CERDOS DE EXPLOTACIONES EXTENSIVAS DE COLOMBIA
Published 2006-01-01“…El presente trabajo tuvo como objetivo actualizar en el país la situación de la infección por el virus del Síndrome reproductivo y respiratorio porcino (PRRS). …”
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3508
Surveillance Following Hepatitis B Surface Antigen Loss: An Issue Requiring Attention
Published 2024-12-01“…However, even after HBsAg loss, hepatitis B virus can persist, with a risk of recurrence, reactivation, cirrhosis, and hepatocellular carcinoma. …”
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3509
The WHO Disease Outbreak News during the Covid-19 pandemic.
Published 2025-01-01“…We find that multinational epidemics of diseases like Ebola virus and MERS-CoV continue to dominate the DON. …”
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3510
COVID-19: Gastrointestinal Manifestations and Complications
Published 2021-11-01“…The virus responsible for the COVID-19 pandemic is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the genus Betacoronavirus. …”
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3511
MODES OF SARS-COV-2 TRANSMISSION
Published 2021-07-01“…On 11th February 2020, the WHO named the disease COVID-19, short for “COronaVIrus Disease 2019”. This COVID-19 out-break has grown substantially to that of pandemic nature currently. …”
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3512
A Metaphorical Approach to Developing Behavior Within the Context of the Covid-19 Pandemic
Published 2022-06-01“…On the other hand, it may be thought that the visuals examined may not convince everyoneto be careful and avoid exposure to the virus. In the study, a social network analysis was also conducted tounderstand the appearance and interaction status of the pandemic in social networks, and the networks‘#evdekal’ (stay at home) and ‘#hayatevesigar’ (life fits into the home) on Twitter were examined. …”
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3513
Herpes Simplex Proctitis Mimicking Inflammatory Bowel Disease in a Teenaged Male
Published 2017-01-01“…Rectal biopsies obtained via colonoscopy were culture-positive for herpes simplex virus (HSV), leading to a diagnosis of HSV proctitis and treatment with an appropriate antiviral medication. …”
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3514
Pandemia y crisis económica: una relación de develación
Published 2020-07-01“…Finalmente, se establece que el rol del virus ha sido des-ocultar la incapacidad sistémica del orden mundial para hacer frente a diversas amenazas, incluida la actual pandemia. …”
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3515
Pneumocystis carinii: A Review of an Important Opportunistic Pathogen in AIDS
Published 1991-01-01“…Individuals with damaged T helper cells secondary to malignancies (eg, Hodgkin’s lymphoma), drugs (eg, cyclosporine, steroids), or certain infections (eg, human immunodeficiency virus) are at particular risk. Serological studies suggest that disease is most often secondary to the reactivation of an asymptomatic infection, usually acquired during childhood. …”
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3516
Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
Published 2018-01-01“…Drug-induced hypersensitivity syndrome (DIHS), also termed as drug reaction with eosinophilia and systemic symptoms (DRESS), is a multiorgan systemic reaction characterized by a close relationship with the reactivation of herpes virus. Published data has demonstrated that among patients with DIHS/DRESS, 75–95% have leukocytosis, 18.2–90% show atypical lymphocytes, 52–95% have eosinophilia, and 75–100% have hepatic abnormalities. …”
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3517
HIV-Related Immune Activation and Inflammation: Current Understanding and Strategies
Published 2021-01-01“…Although antiretroviral therapy effectively controls human immunodeficiency virus (HIV) replication, a residual chronic immune activation/inflammation persists throughout the disease. …”
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3518
A Model System for Concurrent Detection of Antigen and Antibody Based on Immunological Fluorescent Method
Published 2015-01-01“…It will be helpful to screen for both antigen and antibody particularly in the situations of the multiserotype and high-frequency mutant virus infections.…”
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3519
Case report Diagnosis dan Penanganan Feline Panleukopenia
Published 2024-12-01“…Feline panleukopenia (FPL) adalah penyakitinfeksi Feline panleukopenia virus yang menyebabkan mortalitas tinggi pada kucing. …”
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3520
Roles of Interferons in Pregnant Women with Dengue Infection: Protective or Dangerous Factors
Published 2017-01-01“…The severity of dengue is correlated with the level of IFNs, while the serum IFN level must be sufficiently high to maintain the pregnancy and to inhibit virus replication.…”
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