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Fixation and reversion of mutations in the receptor-binding domain of the SARS-CoV-2 spike protein: A 2020–2024 analysis
Published 2024-12-01Subjects: Get full text
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Geographical distribution and evolutionary dynamics of H4Nx avian influenza viruses
Published 2025-01-01Subjects: Get full text
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Order reduction for an RNA virus evolution model
Published 2015-05-01Subjects: Get full text
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A novel isothermal whole genome sequencing approach for Monkeypox Virus
Published 2024-09-01“…Whole genome sequencing (WGS) has been successfully used to keep track of viral evolution during outbreaks or for surveillance of multiple pathogens of public health significance. …”
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NOVEL MUTATIONS IN THE NON-STRUCTURE PROTEIN 2 OF SARS-CoV-2
Published 2023-10-01“…Conclusion: Our study suggested that the mutations as K337D and G392D modulate the stability of nsp2 and tracking viral evolution should be implemented and vaccine development updated. …”
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Phylodynamic reconstruction of major chicken infectious anemia virus clades epidemiology, dispersal, and evolution
Published 2025-01-01“…Accordingly, although significant selective pressures were shaping viral evolution, comparable strengths were estimated in the two viral populations. …”
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Rotavirus in Calves and Its Zoonotic Importance
Published 2021-01-01“…Reassortment is one of the important mechanisms for generating genetic diversity of rotaviruses and eventually for viral evolution. So, the primary strategy is to reduce the burden of rotavirus infections by practicing early colostrum’s feeding in newborn calves, using vaccine, and improving livestock management. …”
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The R203M and D377Y mutations of the nucleocapsid protein promote SARS-CoV-2 infectivity by impairing RIG-I-mediated antiviral signaling.
Published 2025-01-01“…However, its biological function in viral evolution is not well understood. SARS-CoV-2 N protein mutations were analyzed in Delta, Omicron, and original strains. …”
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Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era
Published 2024-04-01“…Keywords: immunocompromised; SARS-CoV-2 infection; monoclonal antibodies; antivirals; persistent infection; viral evolution …”
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Two Years of SARS-CoV-2 Omicron Genomic Evolution in Brazil (2022–2024): Subvariant Tracking and Assessment of Regional Sequencing Efforts
Published 2025-01-01“…The emergence of new subvariants in this new epidemiological scenario underscores the importance of ongoing genomic surveillance to track viral evolution and inform public health strategies, providing valuable information to update vaccines and implement other measures, such as lockdowns, mask usage, social distancing, health education, and self-testing.…”
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Diversity and Potential Cross-Species Transmission of Rotavirus A in Wild Animals in Yunnan, China
Published 2025-01-01“…This study provides critical data for understanding the transmission mechanisms and the RVA host range, and highlights the pivotal role of wildlife in viral evolution and dissemination. These findings have significant implications for public health policies and emphasize the need for enhanced surveillance to prevent interspecies RVA transmission.…”
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Low-Level Zoonotic Transmission of Clade C MERS-CoV in Africa: Insights from Scoping Review and Cohort Studies in Hospital and Community Settings
Published 2025-01-01“…Ongoing research focuses on genomic comparisons between clade C and the more virulent clades A and B, alongside the surveillance of viral evolution. This study highlights the need for continuous monitoring but indicates that MERS-CoV clade C currently poses a minimal public health threat in Africa.…”
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A novel approach to analyzing the evolution of SARS-CoV-2 based on visualization and clustering of large genetic data compactly represented in operative memory
Published 2025-01-01“…Finally, the evolution of distributions of the number of changes (editing distance between each genome and reference sequence) caused by substitutions, deletions and insertions was visualized as 3D surfaces, which clearly show the process of viral evolution over 4.5 years, with a time step = 1 week. …”
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p18 encoded by FgGMTV1 is responsible for asymptomatic infection in Fusarium graminearum
Published 2025-01-01“…This work not only expands our knowledge of the genomovirus proteome but also provides insights into the strategies of viral evolution and adaptation. Moreover, we propose an innovative approach for creating hypovirulent strains utilizing engineered mycoviruses for the biocontrol of plant pathogenic fungi.IMPORTANCEMycovirus-fungus interplay often leads to asymptomatic infections. …”
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Insight into the codon usage patterns and adaptation of Tembusu Virus
Published 2025-01-01“…Codon adaptation index (CAI) analysis reveals that this lineage of TMUV show best adapted to the CUPs of duck than other lineages, underscoring the role of natural selection in shaping viral evolution, a finding in line with evidence that CUPs in the TMUV genome is predominantly shaped by natural selection. …”
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Fc-binding nanodisc restores antiviral efficacy of antibodies with reduced neutralizing effects against evolving SARS-CoV-2 variants
Published 2025-01-01“…Notably, Sotrovimab, an FDA-approved monoclonal antibody that has experienced a significant decline in neutralizing potency due to viral evolution, exhibited robust antiviral activity when complexed with the nanodisc against all tested Omicron variants. …”
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Exploring the recombinant evolution and hosts of crucivirus based on novel oyster-associated viruses
Published 2025-02-01“…“Crucivirus” represents a group of viruses with chimeric genomes, significant for viral evolution and recombination studies. Their capsid proteins share homology with the RNA virus tombusvirus, while their replicase-associated proteins are homologous to a class of single-stranded DNA viruses, namely CRESS DNA viruses. …”
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