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    Rates of viral evolution are linked to host geography in bat rabies. by Daniel G Streicker, Philippe Lemey, Andres Velasco-Villa, Charles E Rupprecht

    Published 2012-01-01
    “…Although the tempo of viral evolution is often ascribed to viral features such as mutation rates and transmission mode, these factors alone cannot explain variation among closely related viruses, where host biology might operate more strongly on viral evolution. …”
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    The mutational landscape of SARS-CoV-2 provides new insight into viral evolution and fitness by Jori Symons, Claire Chung, Bert M. Verheijen, Sarah J. Shemtov, Dorien de Jong, Gimano Amatngalim, Monique Nijhuis, Marc Vermulst, Jean-Francois Gout

    Published 2025-07-01
    “…In this work, we show that the biased mutation spectrum of SARS-CoV-2 is likely a result of frequent cytidine deamination and that the secondary structure of the virus plays an important role in this process, providing new insight into the parameters that guide viral evolution and highlighting fundamental weaknesses of the virus that may be exploited for therapeutic purposes.…”
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    Higher Rates of Viral Evolution in Chronic Hepatitis B Patients Linked to Predicted T Cell Epitopes by Magnus Illum Dalegaard, Anni Winckelmann, Ulrik Fahnøe, Alexander P. Underwood, Anders Gorm Pedersen, Signe Bollerup, Jens Bukh, Nina Weis

    Published 2025-05-01
    “…This study aims to compare intra-individual viral evolution in two groups of chronic hepatitis B (CHB) patients, using antiviral treatment initiation as a measure of lack of immunological control. …”
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    Apollo: a comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell by Deshan Perera, Evan Li, Paul MK Gordon, Frank van der Meer, Tarah Lynch, John Gill, Deirdre L. Church, A. P. Jason de Koning, Christian D. Huber, Guido van Marle, Alexander Platt, Quan Long

    Published 2025-07-01
    “…Abstract Modern sequencing instruments bring unprecedented opportunity to study within-host viral evolution in conjunction with viral transmissions between hosts. …”
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