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1821
Knowledge, attitudes and behaviour towards ticks and tick-borne diseases—A survey among Lyme borreliosis cases in Bavaria in 2019
Published 2025-01-01“…In Bavaria, the average annual incidence of reported cases was 34.3 cases per 100,000 inhabitants between 2013 and 2020, although case numbers were presumed to be substantially higher. Since no vaccine against LB is currently available, prevention focuses on individual protection measures. …”
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1822
Discovery of anti-Ebola virus multi-target inhibitors from traditional Chinese medicine database using molecular screening, biophysical investigation, and binding free energy calcu...
Published 2025-02-01“…The lack of effective treatment or vaccine for this pathogen poses a serious threat to a global pandemic. …”
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1823
Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada
Published 2025-02-01“…In period #2, the hazard of infection was higher among HCWs who had COVID-19-infected children at home, whereas the use of protective measures in the community (maintaining social distance, mask-wearing) and receiving a vaccine booster were associated with reduced risk. …”
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1824
Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial
Published 2025-02-01“… BackgroundInvasive meningococcal disease (IMD) is a serious, vaccine-preventable infectious disease that can be life-threatening. …”
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1825
Optimizing Tongue Fluid Sampling and Testing Protocols for Enhanced PRRSV Isolation from Perinatal Swine Mortalities
Published 2025-01-01“…Isolating PRRSV is essential for identifying infectious viruses and for vaccine formulation. This study evaluated the potential of using tongue fluid (TF) from perinatal piglet mortalities for PRRSV isolation. …”
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1826
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1827
Extracellular vesicles from fifth-stage larval Angiostrongylus cantonensis upregulate cholesterol biosynthesis and suppress NLRP2-associated inflammatory responses in mouse astrocy...
Published 2025-01-01“…This study highlights the immunomodulatory roles of L5 EVs in non-permissive hosts, suggesting their potential as therapeutic targets and vaccine candidates against A. cantonensis.…”
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1828
Methods to Adjust for Confounding in Test-Negative Design COVID-19 Effectiveness Studies: Simulation Study
Published 2025-01-01“… BackgroundReal-world COVID-19 vaccine effectiveness (VE) studies are investigating exposures of increasing complexity accounting for time since vaccination. …”
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1829
Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells
Published 2025-02-01“…BackgroundAlthough the immune response of host T cells to human immunodeficiency virus (HIV) significantly influences the progression of the infection, the development of T-cell-based vaccines and therapies, as well as the clinical evaluation of specific T-cell functions, is currently markedly hindered by the absence of broad-spectrum, functionally validated HIV T-cell epitopes that account for the polymorphisms of the human leukocyte antigen (HLA) within an indicated geographic population. …”
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1830
Resurgence of Mumps among Lower Socioeconomic Class of Children in Ahmedabad: A Cross-sectional Study of 115 Cases in a Tertiary Care Center
Published 2024-05-01“…No patient was fully vaccinated for mumps. Out of the 15.6% (18 patients) admitted, two patients (1.7%) suffered from mumps complication of orchitis. …”
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1831
Incidence and predictors of respiratory tract infections among birth cohorts in Ethiopia, 2023
Published 2025-02-01Get full text
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1832
Proficiency, Clarity, and Objectivity of Large Language Models Versus Specialists’ Knowledge on COVID-19's Impacts in Pregnancy: Cross-Sectional Pilot Study
Published 2025-02-01“…Overall, ChatGPT-4, Microsoft Copilot, and Google Bard generally provided accurate, updated information on COVID-19 and vaccines in maternal and fetal health, aligning with health guidelines. …”
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1833
Seroprevalence of SARS-CoV-2 Infection Among People Living with HIV in Libreville, Gabon
Published 2024-12-01“…However, having a detectable viral load (<i>p</i> = 0.0001), being vaccinated (COVID-19 vaccine, <i>p</i> = 0.04), and a history of COVID-19 (<i>p</i> < 0.0001) symptoms were associated with a higher risk of having anti-SARS-CoV-2 antibodies. (4) Conclusions: By early 2023, PLHIV in Gabon had high rates of SARS-CoV-2 seropositivity. …”
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1834
Pulmonary aspergillosis in US Veterans with COVID-19: a nationwide, retrospective cohort study
Published 2025-01-01“…Selected clinical characteristics included age >70, receipt of immune-compromising drugs, hematologic malignancy, chronic respiratory disease, vaccination status, and vaccine era. Multivariate logistic regression was used to estimate the independent effects of these variables via adjusted odds ratios (aOR). …”
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1835
Prevalence, Incidence and Predictors of Anal HPV Infection and HPV-Related Squamous Intraepithelial Lesions in a Cohort of People Living with HIV
Published 2025-01-01“…A CD4 cell count > 500/mmc was an independent predictor of HPV clearance. HPV vaccination was performed on 30.9% of patients. A trend toward an increased clearance of HPV genotypes included in 9-valent vaccine was observed in vaccinated patients (40.6% versus 30.8% in unvaccinated, <i>p</i> = 0.079). …”
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1836
From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes
Published 2025-02-01“…These findings improve our understanding of virus–host interactions and provide a promising approach to modified live vaccine development.IMPORTANCEA better understanding of the interactions between viruses and their hosts is a crucial step in the development of strategies for controlling viral diseases, such as vaccines and antivirals. …”
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1837
Chemical Synthesis, Efficacy, and Safety of Antimalarial Hybrid Drug Comprising of Sarcosine and Aniline Pharmacophores as Scaffolds
Published 2020-01-01“…Currently, there is no effective vaccine for malaria control. In addition, although there are effective drugs for treatment of malaria, this could be lost to the drug resistance in different Plasmodium species. …”
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1838
Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages
Published 2025-02-01Get full text
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1839
Policy brief: Optimising antimicrobial usage in paediatric inpatient hospital settings
Published 2024-04-01Get full text
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1840
Population genetic analysis of clinical Mycobacterium abscessus complex strains in China
Published 2025-01-01Get full text
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