Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation. by Louis Kuijpers, Evdokia-Anastasia Giannopoulou, Yuzhen Feng, Wouter van den Braak, Abbas Freydoonian, Ramon Ramlal, Hugo Meiring, Belén Solano, Wouter H Roos, Arjen J Jakobi, Leo A van der Pol, Nynke H Dekker

“…To counteract hand, foot, and mouth disease-causing viruses such as enterovirus A71 and coxsackievirus A6, virus-like particles (VLPs) have emerged as a leading contender for the development of a multivalent vaccine. However, VLPs have shown rapid conversion from a highly immunogenic state to a less immunogenic state and low particle integrity lifetimes compared to inactivated virus vaccines, thus raising concerns about their overall stability. …”
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Role of Infection in Neurologic and Psychiatric Diseases by Marylou V. Solbrig, Guey Chuen Perng

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Meta-Analysis of Pulmonary Transcriptomes from Differently Primed Mice Identifies Molecular Signatures to Differentiate Immune Responses following Bordetella pertussis Challenge by René H. M. Raeven, Jeroen L. A. Pennings, Elly van Riet, Gideon F. A. Kersten, Bernard Metz

“…Complement-mediated responses were more prominent in mice immunized with an outer membrane vesicle pertussis vaccine than in mice that received a whole-cell pertussis vaccine. …”
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Canine adenovirus serotype 2 isolation and determination of its cultivation parameters by A. A. Klimova

“…Primarily, the virus strains currently important and circulating in the particular territory shall be used for vaccine production to induce long-term and strong immunity in animals. …”
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Antiviral Activity and Underlying Mechanism of <i>Moslae herba</i> Aqueous Extract for Treating SARS-CoV-2 by Yan Feng, Qiong Ge, Jian Gao, Zhuoying Wu, Yunyi Zhang, Haiyan Mao, Beibei Wu, Changping Xu

“…Despite the widespread use of COVID-19 vaccines, there is still a global need to find effective therapeutics to deal with the variants of SARS-CoV-2. …”
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Immunomodulation Induced by Host Pathogen Interaction by Hadi M. Yassine, Syed M. Moin, Farhan S. Cyprian, Adam K. Wheatley, Gheyath K. Nasrallah

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Unvaccinated COVID-19 Pneumonia- a family affair by Trilok Stead, Michael Hughes, Frank Fraunfelter, Vashun Rodriguez, Latha Ganti

“…This case illustrates the complexities of vaccine hesitancy and societal misinformation.…”
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Enhanced Porcine Reproductive and Respiratory Syndrome Virus Replication in Nsp4- or Nsp2-Overexpressed Marc-145 Cell Lines by Zhengqin Ye, Zhenbang Zhu, Liangzheng Yu, Zhendong Zhang, Xiangdong Li

“…Porcine reproductive and respiratory syndrome (PRRS) causes significant economic losses to the swine industry. The killed PRRSV vaccine has been reported to be safe and could elicit humoral responses. …”
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Tetanus Toxoid Immunization Status and Associated Factors among Mothers in Damboya Woreda, Kembata Tembaro Zone, SNNP, Ethiopia by Muluken Dubale Mamoro, Lolemo Kelbiso Hanfore

“…Even though most mothers had access for TT immunization service, they were not immunized with protective doses of TT vaccine.…”
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Expression of Helicobacter pylori hspA Gene in Lactococcus lactis NICE System and Experimental Study on Its Immunoreactivity by Xiao-Juan Zhang, Shu-Ying Feng, Zhi-Tao Li, Yan-Ming Feng

“…The aim of this study was to develop an oral Lactococcus lactis (L. lactis) vaccine against Helicobacter pylori (H. pylori). Methods. …”
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Multiplayer games and HIV transmission via casual encounters by Stephen Tully, Monica-Gabriela Cojocaru, Chris T. Bauch

“…We study the sensitivity of Nash strategies with respect to varying preference rankings, and the impact of a prophylactic vaccine introduced in players of youngest age groups. …”
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Leveraging Quantum LSTM for High-Accuracy Prediction of Viral Mutations by Prashanth Choppara, Bommareddy Lokesh

“…The rapid mutations of viruses such as COVID-19 pose significant challenges for vaccine development and effective disease management. …”
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An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…All mice were given a quadrivalent influenza vaccine at 3 µg/animal via intramuscular injection 14 days before the end of the study. …”
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The Efforts to Implement a Malaria Elimination Strategy in The Highly Endemic Malaria Region of Papua Province, Indonesia by Erni Juwita Nelwan

“…Indonesia has recently completed a malaria vaccine trial, the IDSPZV1, which included the PfSPZ Vaccine and PfSPZ-CVac (CQ), conducted among soldiers deployed to Papua Province, New Guinea, for 10 months. …”
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Mitigation of the biosafety risks of sars-cov-2 at bsl-3 laboratories by Mustafa Sencer Karagül, Orbay Sayı, Mevlüt Demirbaş, Fahriye Saraç, Mustafa Hasöksüz

“…<b>Aim:</b> The aim of this study is to reduce the biosafety risks of laboratory exhaust air due to SARS-CoV-2 at a biosafety level-3 laboratory used for vaccine development against COVID-19 pandemic.<p> <b>Materials and Methods: </b>In this study, the infrastructure and the organisation of the containment laboratory, which aimed to be used to struggle with pandemic, was used for risk assessment. …”
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Isolation, Serotyping, and Molecular Detection of Bovine FMD Virus from Outbreak Cases in Abaʼala District of Afar Region, Ethiopia by Teshager Dubie, Tsedale Amare

“…Hence, region-wise FMD outbreak investigation, further phylogenetic analysis, and vaccine matching field isolates should be carried out for effective vaccine development to control the disease.…”
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Isolation and Antibiotic Susceptibility Testing of Haemophilus influenzae from Nasopharynx of Children under Five Years Attending Maternal and Child Health Clinic in Mbarara Region... by Daniel Omoding, Joel Bazira

“…H. influenzae remains an organism of a major public health challenge worldwide despite the availability of the Hib vaccine, particularly among children under 5 years. …”
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Developing a clinical prediction model to modify empirical antibiotics for non-typhoidal Salmonella bloodstream infection in children under-five in the Democratic Republic of Congo by Bieke Tack, Daniel Vita, Jules Mbuyamba, Emmanuel Ntangu, Hornela Vuvu, Immaculée Kahindo, Japhet Ngina, Aimée Luyindula, Naomie Nama, Tito Mputu, Justin Im, Hyonjin Jeon, Florian Marks, Jaan Toelen, Octavie Lunguya, Jan Jacobs, Ben Van Calster

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Detection of infectious laryngotracheitis virus in a peacock by A. A. Kozlov, N. S. Mudrak, I. A. Chvala

“…High level of similarity with vaccine strains «0» (FGBI «ARRIAH» and Serva (Nobilis ILT) used in poultry production in Vladimir oblast in analyzed genome section (99,5%) was demonstrated.…”
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Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthoha... by Jing Wei, Hui Zhang, Jiawei Pei, Qiqi Yang, Yuan Wang, Xiaolei Jin, He Liu, Liang Zhang, Hongwei Ma, Linfeng Cheng, Yangchao Dong, Yingfeng Lei, Yinlan Bai, Zhikai Xu, Pengbo Yu, Fanglin Zhang, Wei Ye

“…Currently, the inactive vaccine licensed in endemic areas elicit low levels of neutralizing antibodies (NAbs). …”
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