Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy by Fermín E. González, Alexey Chernobrovkin, Cristián Pereda, Tamara García-Salum, Andrés Tittarelli, Mercedes N. López, Flavio Salazar-Onfray, Roman A. Zubarev

“…During the last decade, we demonstrated that vaccination of advanced melanoma patients with autologous tumor antigen presenting cells (TAPCells) loaded with an allogeneic heat shock- (HS-) conditioned melanoma cell-derived lysate (called TRIMEL) is able to induce an antitumor immune response associated with a prolonged patient survival. …”
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Comparison of air-liquid interface transwell and airway organoid models for human respiratory virus infection studies by Camilla T. Ekanger, Camilla T. Ekanger, Camilla T. Ekanger, Nilima Dinesh Kumar, Rosanne W. Koutstaal, Fan Zhou, Martin Beukema, Joanna Waldock, Simon P. Jochems, Noa Mulder, Cécile A. C. M. van Els, Cécile A. C. M. van Els, Othmar G. Engelhardt, Nathalie Mantel, Kevin P. Buno, Karl Albert Brokstad, Karl Albert Brokstad, Agnete S. T. Engelsen, Agnete S. T. Engelsen, Rebecca J. Cox, Rebecca J. Cox, Barbro N. Melgert, Barbro N. Melgert, Anke L. W. Huckriede, Puck B. van Kasteren

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Testing of chickens experimentally infected with A/H9N2 avian influenza virus isolates for their immune responses by O. S. Osipova, M. A. Volkova, S. V. Frolov, D. B. Andreychuk, I. A. Chvala

“…According to literature data, immune response activated by vaccination induces the reverse dynamics towards to increase in CD4⁺/CD8⁺ ratio. …”
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Overview of animal infectious disease situation in the Republic of Dagestan in 2023 by M. M. Mikailov, N. R. Budulov, Sh. A. Gunashev, E. A. Yanikova

“…Anti-epizootic measures taken in the past year included a total of 93.8 million vaccinations and 6.2 million tests performed in the diagnostic institutions. …”
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Teenage Pregnancy: Impact of the Integral Attention Given to the Pregnant Teenager and Adolescent Mother as a Protective Factor for Repeat Pregnancy by Maria José Carvalho Sant'Anna, Kepler Alencar Mendes Carvalho, Amanda Melhado, Verônica Coates, Hatim A. Omar

“…One year after birth, 67.5% studied, 50% worked, 55.1% lived with the partner, 77% correctly used contraceptives, every child lived with their mothers and their vaccinations were up to date. The results demonstrate that the global attention given to the health of adolescent mothers and pregnant adolescents is a protective factor for pregnancy relapse and quality of life.…”
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Development and Validation of Rabies Health Education Module (RaHEM) for Dog Owners in Kelantan, Malaysia: An ADDIE Model by Mohammad Fazrul Mohammad Basir, Suhaily Mohd Hairon, Mohd Ismail Ibrahim, Wan Mohd Zahiruddin Wan Mohamad, Nik Mohd Hafiz Mohd Fuzi, Ainin Syakirah Rosli, Mohammad Sabri Abdul Rahman, Anas Rosedi

“…Despite the availability of effective vaccines for both humans and animals, the persistence of rabies-related fatalities underscores the need for enhanced public education strategies. …”
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The Ukrainian war and the pandemic: the impact on public health and the need for new health digital tools and the next level of intelligence by M. Geanta, B. Cucos, A. Boata, A.C. Nuta, F.M. Nuta, V.V. Semenov

“…Pandemic restrictions in the European region are being lifted despite low vaccination rates in Central and Eastern European countries and a lack of effective containment strategies. …”
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Influenza D virus in cattle (review) by S. V. Koteneva, A. G. Glotov, T. I. Glotova, A. V. Nefedchenko

“…There are currently no vaccines or specific treatment for influenza D virus. …”
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Harmonizing population health data into OMOP common data model: a demonstration using COVID-19 sero-surveillance data from Nairobi Urban Health and Demographic Surveillance System by Michael Ochola, Sylvia Kiwuwa-Muyingo, Tathagata Bhattacharjee, David Amadi, Maureen Ng’etich, Damazo Kadengye, Henry Owoko, Boniface Igumba, Jay Greenfield, Jim Todd, Agnes Kiragga, Agnes Kiragga

“…The standardized dataset included information on demographics, COVID-19 symptoms, vaccination, and COVID-19 antibody test results.ConclusionsThe OMOP CDM is a valuable tool for harmonizing observational health data. …”
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A Proposed Information System for Communicating Foot-and-Mouth Disease Events among Livestock Stakeholders in Gairo District, Morogoro Region, Tanzania by Ahmed Kijazi, Michael Kisangiri, Shubi Kaijage, Gabriel Shirima

“…The data shows that 78% of livestock keepers in Gairo district had already observed FMD infection in their cattle, and the pastoral communities were mostly affected. Currently, vaccination is the main tool for controlling FMD because there are no therapeutic intervention tools. …”
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Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer by Nirmala Ghimirey, Chase Steele, Brian J. Czerniecki, Gary K. Koski, Loral E. Showalter

“…To explore the possibility of combining targeted drugs with Th1-polarizing vaccines, we undertook a study to examine the impact of combining Th1 cytokines with the relatively broad-spectrum receptor tyrosine kinase antagonist, sunitinib. …”
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Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask by Adam F. Parlin, Mikhail Yermakov, Samuel M. Stratton, Susan R. Reutman, Theresa M. Culley, Patrick A. Guerra, Sergey A. Grinshpun

“…Abstract In spite of the remarkable progress made in the development of safe and effective vaccines against COVID-19, deployment of respiratory protective devices remains vital for mitigating the transmission of SARS-CoV-2 during the ongoing pandemic. …”
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Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Eff... by Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

“…Positive outcome was the abrogation of polymerase activity increasing safety of RT-based DNA vaccines. Identification of the molecular determinants of low cellular immunogenicity of RT requires further studies.…”
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Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells by Hongzhuan Zhou, Huanhuan Zhang, Xia Su, Fuzhou Xu, Bing Xiao, Jin Zhang, Qi Qi, Lulu Lin, Kaidi Cui, Qinqin Li, Songping Li, Bing Yang

“…This study lays the foundation for elucidating the potential function of CPV VP2 protein in the process of viral infection and proliferation which provides a theoretical basis for the design of antiviral agents and vaccines.…”
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The length of price&reimbursement negotiation procedures in Italy in the period 2021-2023 was independent from the price of medicines by Raffaella Cocciolo, Paola Turella, Daniela Pilunni, Pierluigi Navarra

“…Biosimilars, generics, gene therapies, Sars-Cov-2 vaccines and medicines with no negotiated price at the datalock of December 2023 were excluded from the analysis. …”
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TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders by Nincy Debeuf, Sahine Lameire, Manon Vanheerswynghels, Julie Deckers, Caroline De Wolf, Wendy Toussaint, Rein Verbeke, Kevin Verstaen, Hamida Hammad, Stijn Vanhee, Bart N Lambrecht

“…After immunization with Spike/CpG-motifs, mRNA vaccination or SARS-CoV-2 infection, CORSET8 T cells strongly proliferated and showed signs of T cell activation. …”
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Rapid aging of influenza epidemics in China from 2005/06 to 2016/17: A population-based study by Weibo Tang, Hao Lei, Nan Zhang, Yaojing Wang, Shimeng Cai, Shuyi Ji, Lei Yang, Mengya Yang, Can Chen, Shigui Yang, Dayan Wang, Yuelong Shu

“…This finding highlights the importance of influenza vaccination among older individuals in China.…”
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Genetic proxies for clinical traits are associated with increased risk of severe COVID-19 by N. J. M. Chaddock, S. S. R. Crossfield, M. Pujades-Rodriguez, M. M. Iles, A. W. Morgan

“…PRS were optimized for 23 clinical variables and related traits previously-associated with severe COVID-19 in up to 450,449 UK Biobank participants, and tested in 9,560 individuals diagnosed in the pre-vaccination era. Associations were further adjusted for (i) sociodemographic and (ii) clinical variables. …”
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Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen by Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

“…Our study suggests a temporal window soon after BCG vaccination, in which STAT1-dependent activation of long-lived resident cells in the tissue mediates localized protection.…”
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A functional approach to analyze the genetic basis for differences in virulence of monkeypox virus clades by Patricia L. Earl, Jeffrey L. Americo, Sara Reynolds, Wei Xiao, Catherine Cotter, Bernard Moss

“…Determination of the genetic basis for these differences could help to develop improved therapeutics and vaccines. The Castaneous (CAST) mouse is highly susceptible to MPXV and virulence differences of MPXV clades are statistically significant mimicking their relative severities in humans. …”
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