Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection by Zeyu Liu, Xue Li, Xiaohong Li, Xingyu Yan, Yuan Tian, Yue Zhao, Kexin Liu, Pei Hao, Shuye Zhang, Chao Zhang

“…Licensed inactivated EV-A71 vaccines do not provide cross-protection against other enteroviruses. …”
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Targeted Anticancer Immunotoxins and Cytotoxic Agents with Direct Killing Moieties by Koji Kawakami, Oumi Nakajima, Ryuichi Morishita, Ryozo Nagai

“…Despite the progress of the bioinformatics approach to characterize cell-surface antigens and receptors on tumor cells, it remains difficult to generate novel cancer vaccines or neutralizing monoclonal antibody therapeutics. …”
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Severe Cases of Tick-Borne Encephalitis in Northeastern Poland by Justyna Adamczuk, Magdalena Chlabicz, Natalia Koda, Maciej Kondrusik, Joanna Zajkowska, Piotr Czupryna, Anna Moniuszko-Malinowska

“…Both of our patients were not vaccinated despite the World Health Organization’s (WHO’s) recommendations. …”
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Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease by Long Fung Chau, Simon Lillico, Tanja Opriessnig, Rosemary Blake, Luc Tardy, Chen-Hsuin Lee, Scott Maxwell, Claire Warren, Elizabeth Thornton, Catherine L. Mclaughlin, Gerry McLachlan, Christine Tait-Burkard, Sarah Fletcher, Stephen Anderson, Sharon Brown, Louise Gibbard, Thomas Tzelos, Dawn MacMillan-Christensen, J. Kenneth Baillie, David A. Dorward, David J. Griffiths, Finn Grey

“…Abstract Animal models that accurately reflect COVID-19 are vital for understanding mechanisms of disease and advancing development of improved vaccines and therapeutics. Pigs are increasingly recognized as valuable models for human disease due to their genetic, anatomical, physiological, and immunological similarities to humans, and they present a more ethically viable alternative to non-human primates. …”
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ASSISTED REPRODUCTIVE TECHNOLOGY BETWEEN MEDICINE, RELIGION AND LAW by Dan LUPAȘCU, Ioana PĂDURARIU

“…That is what we do by nature: we figure out how things work and we make new steps, over and over. We created vaccines to help prevent diseases and, in the future, maybe we are about to create a human being outside the womb. …”
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Antihepatitis B Virus Activity of a Protein-Enriched Fraction from Housefly (Musca domestica) in a Stable HBV-Producing Cell Line by Xuemei Lu, Xiaobao Jin, Jie Wang, Fujiang Chu, Jiayong Zhu

“…Hepatitis B virus (HBV) infection remains a major public health problem. Although several vaccines and therapeutic strategies are currently being implemented to combat HBV virus, effective antiviral therapy against HBV infection has not been fully developed. …”
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Current advancements in microneedle technology for therapeutic and biomedical applications by Olivia Sen, Poulami Poddar, Poulami Sarkar, Sanchita Das, Sreejan Manna

“…Silicon, stainless steel, polymers, coating materials, biodegradable materials, several crosslinking techniques and biosensing devices are used to fabricate microneedles. can be employed as a leading novel technology for drug administration, vaccinations, cosmetics, diagnostics, tissue engineering, cancer studies, and wound care. …”
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Effectiveness of Mobile Health Services in Remote Papua under Indonesia’s Minister of Health Regulation No. 90 of 2015 by Nora Lelyana, Aris Sarjito

“…The findings reveal that MHS has significantly enhanced access to essential services, including maternal and child health, vaccinations, and primary care, while alleviating travel burdens for isolated populations. …”
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Stress and Coping Among Elderly During The COVID-19 Pandemic in Sulaimanya City in Kurdistan Region of Iraq by Yousif Abdalla Qadr, Azad Ali Ismail

“…Male participants, elders who live with their family, unvaccinated elders, physically passive elders have had higher stress level than female, elderly home, vaccinated, physical active elders. The findings also indicated that spiritual connection was the most common coping method used by the sample. …”
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GENETIC CHARACTERIZATION OF AVIAN INFECTIOUS BRONCHITIS VIRUS ISOLATES RECOVERED IN CIS COUNTRIES IN 2015–2017 by L. O. Scherbakova, S. N. Kolosov, Z. B. Nikonova, N. G. Zinyakov, Ye. V. Ovchinnikova, I. A. Chvala

“…The mutation frequency in the hypervariable region of the S1 gene of the virus isolated from the vaccinated birds annually amounts to 1.5%. Long-term observations of the circulation of IBV isolates detected in a number of poultry farms demonstrated that the virus genetic lineages circulating on the poultry farms could eventually change. …”
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Towards designing improved cancer immunotherapy targets with a peptide-MHC-I presentation model, HLApollo by William John Thrift, Nicolas W. Lounsbury, Quade Broadwell, Amy Heidersbach, Emily Freund, Yassan Abdolazimi, Qui T. Phung, Jieming Chen, Aude-Hélène Capietto, Ann-Jay Tong, Christopher M. Rose, Craig Blanchette, Jennie R. Lill, Benjamin Haley, Lélia Delamarre, Richard Bourgon, Kai Liu, Suchit Jhunjhunwala

“…Abstract Based on the success of cancer immunotherapy, personalized cancer vaccines have emerged as a leading oncology treatment. …”
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Prognostic significance of tumor angiogenesis markers in advanced cervical cancer undergoing chemotherapy by I Nyoman Bayu Mahendra, I Gde Sastra Winata, William Alexander Setiawan, Ida Bagus Agung Widnyana Putra, Putu Bagus Darmayasa

“…Despite advancements in screening programs and vaccination efforts, a significant proportion of patients present with advanced-stage disease, characterized by severe manifestations and a poor prognosis. …”
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Triple Viral Infections in Advanced Breast Cancer: Insights from a Three-Case Report and Literature Review by Ashraf I. Khasawneh, Nisreen Himsawi, Mohammed Alorjani, Hadeel Al-Momani, Uruk Shahin, Ashraf Sammour, Tareq Saleh, Hafez Al-Momani, Rame Khasawneh, Sofian Al Shboul

“…<b>Conclusions:</b> The findings contribute to growing evidence that viral infections may influence the progression and therapeutic response of breast cancer, warranting further investigation into targeted preventive measures including vaccinations.…”
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Artificial neural networks for stability analysis and simulation of delayed rabies spread models by Ramsha Shafqat, Ateq Alsaadi

“…This study addressed the complexity of rabies spread by integrating two critical delay effects—vaccination efficacy and incubation duration—into a delay differential equations model, capturing more realistic infection patterns between dogs and humans. …”
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Interactions between Leishmania braziliensis and Macrophages Are Dependent on the Cytoskeleton and Myosin Va by Elisama Azevedo, Leandro Teixeira Oliveira, Ana Karina Castro Lima, Rodrigo Terra, Patrícia Maria Lourenço Dutra, Verônica P. Salerno

“…Leishmaniasis is a neglected tropical disease with no effective vaccines. Actin, microtubules and the actin-based molecular motor myosin Va were investigated for their involvement in Leishmania braziliensis macrophage interactions. …”
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Role of extracellular vesicles in the pathogenesis of mosquito-borne flaviviruses that impact public health by Pedro Pablo Martínez-Rojas, Verónica Monroy-Martínez, Blanca H. Ruiz-Ordaz

“…This review focuses on the roles of extracellular vesicles in the pathogenesis of mosquito-borne flavivirus diseases: how they contribute to viral cycle completion, cell-to-cell transmission, and cellular responses such as inflammation, immune suppression, and evasion, as well as their potential use as biomarkers or therapeutics (antiviral or vaccines). We highlight the current findings concerning the functionality of extracellular vesicles in different models of dengue virus, Zika virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus infections and diseases. …”
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Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine by Vijay Kumar

“…On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
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cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values by Danyang Zhang, Bingxue Zhang

“…Gynecological cancers, including cervical, ovarian, and endometrial malignancies, remain a significant global health burden, exacerbated by disparities in access to preventive measures such as HPV vaccination and routine screening. The cGAS/STING signaling pathway, a pivotal mechanism in innate immunity, detects cytosolic DNA from pathogens or cellular damage, triggering immune responses via type I interferons and inflammatory cytokines. …”
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Investigation of prevalence and risk factors of parvovirus infection in dogs in erzurum province, turkey by Walied Fadulalseed Ahmed Ismail, Basak Hanedan

“…<p> <b>Results: </b>In this study, it was determined that there was an important association between the presence of CPV and vaccination status, housing place, cleanliness frequency of housing place, anthelmintic treatment as well as anorexia, vomiting, dehydration and abdominal pain findings.…”
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Molecular Detection and Characterization of Pasteurella multocida Infecting Camels in Marsabit and Turkana Counties, Kenya by Justus K. Kasivalu, George I. Omwenga, Gabriel O. Aboge

“…Farmers should not underfeed camels, ensure appropriate medication and vaccination programs, and minimize herding of camels in crowded areas especially in wet conditions in order to slow the spread of P. multocida infection.…”
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