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2741
Análise dos padrões espaço-temporais das internações por diarreia e do clima nas capitais brasileiras
Published 2019-11-01“…The study found that factors such as seasonality and climate-related are relevant in the analysis of DGOIP occurrence patterns, and continuous observation of hospitalizations should be performed to detect changes in seasonal patterns of the disease, notably considering the wide coverage of child vaccination for rotavirus in Brazil.…”
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2742
Camel milk is a neglected source of brucellosis among rural Arab communities
Published 2025-01-01“…Control is largely via vaccination of small ruminant and cattle populations. …”
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2743
Expression of Proinflammatory and Regulatory Cytokines via NF-κB and MAPK-Dependent and IFN Regulatory Factor-3-Independent Mechanisms in Human Primary Monocytes Infected by Mycob...
Published 2011-01-01“…Thus, by inducing a specific cytokine profile, Mtb can influence the immunoregulatory properties of monocytes, which represent important target of novel vaccinal strategies against Mtb infection.…”
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2744
Quinoline and Quinazoline Alkaloids against COVID-19: An In Silico Multitarget Approach
Published 2021-01-01“…Although, recently, vaccines have been approved for the prevention of COVID-19, there is still an urgent need for the discovery of more efficacious and safer drugs especially from natural sources. …”
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2745
Local and Systemic Antibody Responses in Humans with Helicobacter pylori Infection
Published 1999-01-01“…These studies suggest that the success of antihelicobacter immunization may be due to the ability of vaccination to induce an immune response against antigens that are normally not immunodominant during the course of infection.…”
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2746
Batavia in Crisis: Disease Outbreaks and Public Health Responses in the 20th Century
Published 2024-07-01“…However, the introduction of mass vaccination programs in the 1910s and 1920s marked a turning point, demonstrating the potential of public health interventions in mitigating disease outbreaks. …”
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2747
Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses
Published 2025-01-01“…These advancements have paved the way for lipid-based vaccines and immunotherapies through the application of nanoparticles and synthetic lipid antigens designed to boost immune responses against cancers and infectious diseases. …”
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2748
Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting
Published 2025-01-01“…Such tools facilitated the search for potential therapeutic agents and accelerated epidemiological studies on post-infection and post-vaccination humoral immunity. This review focuses on the use of pseudoviruses as a model for large-scale applications to study enveloped viruses.…”
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2749
Fundamentals and Methods for T- and B-Cell Epitope Prediction
Published 2017-01-01“…There is great interest in identifying epitopes in antigens for a number of practical reasons, including understanding disease etiology, immune monitoring, developing diagnosis assays, and designing epitope-based vaccines. Epitope identification is costly and time-consuming as it requires experimental screening of large arrays of potential epitope candidates. …”
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2750
Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
Published 2022-09-01“…To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. …”
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2751
The Prospects for the Therapeutic Implications of Genetically Engineered Probiotics
Published 2020-01-01“…The lactic acid bacilli are predominantly opposite as they already have gained attention owing to their health-promoting benefits and their safety for human consumption; therefore, their use, especially as a delivery agent of vaccines and drugs, is gaining attention. The tailoring of probiotic strains will not only improve the data regarding the probiotic potential of these strains but also clinch the doubts concerning these probiotics. …”
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2752
In situ-formed cryomicroneedles for intradermal cell delivery
Published 2024-02-01“…As a proof-of-concept, we examined the loading and intradermal delivery of three cell types in clinically relevant in vitro and in vivo models, including mesenchymal stem cells for wound healing, melanocytes for vitiligo treatment, and antigen-pulsed dendritic cells for cancer vaccination.…”
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2753
Abuse potential of fentanyl and fentanyl analogues
Published 2024-11-01“…Conclusions: By educating patients and physicians, making rescue kits easily accessible, developing vaccines to prevent opioid addiction, and perhaps even creating new tamper-resistant fentanyl formulations, it may be possible to prevent fentanyl misuse, therapeutic errors, and the repercussions that follow.…”
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2754
Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations
Published 2025-03-01“…By collating current knowledge, this review underscores the urgent need for the development of targeted vaccines and therapeutic interventions to mitigate the growing threat of EEEV, particularly in the context of climate change-driven geographical expansion.…”
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2755
Analysis of Passenger Satisfaction as a Mediator of Repurchase Intention on Flights with International Routes
Published 2024-12-01“…But as the time goes on, numbers of vaccination found to be effective to eliminate the pandemic. …”
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2756
Evaluation of the Primary Healthcare attributes in a municipality located in the countryside of São Paulo State – Brazil
Published 2015-01-01“…Proper adaptations should be performed during the opening hours of the healthcare centers; facilitating access and appointment scheduling; improve the counter-reference and reference system; offer vaccination and stitch services; and also, improve the communication between professionals and users, review and reformulate the attendance model of the FHS…”
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2757
National Consensus for the Management of Acute Gastroenteritis in Jordanian Children: Consensus Recommendations Endorsed by the Jordanian Paediatric Society
Published 2022-01-01“…The prevention of diarrhoeal diseases should focus on the improvement of nutrition, hygiene, and sanitation, the introduction of routine vaccination against rotavirus, and the adoption of a standardised approach for AGE management (oral rehydration solution (ORS) use±adjunct therapies, continued feeding, and avoiding routine antibiotic use). …”
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2758
The Disappearance of COVID-19 Data Dashboards: The Case of Ephemeral Data
Published 2025-01-01“…Data dashboards tracked global and country-specific statistics and provided cartographic visualizations of cases, deaths, vaccination rates and other metrics. We examined the role of geospatial data on COVID-19 dashboards in the form of maps, charts, and graphs. …”
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2759
The Societal Impact of Herpes Zoster and Postherpetic Neuralgia on Patients, Life Partners, and Children of Patients in Germany
Published 2014-01-01“…We need to raise the awareness of the general public about the real life impact of HZ and PHN and their often severe, debilitating consequences and the potential benefits from vaccination.…”
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2760
Hepatitis B Virus in Polish Blood Donors in the Period 2005–2019—Significant Changes in Epidemiology and Demographic Characteristics of Infected Donors
Published 2025-01-01“…Pursuant to the WHO guidelines, obligatory vaccination was introduced in 1994–1996 (as a part of hepatitis B prophylaxis for newborns), and in 2000–2011, all 14-year-olds were vaccinated. …”
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