Is joint hypermobility linked to self-reported non-recovery from COVID-19? Case–control evidence from the British COVID Symptom Study Biobank by Hugo D Critchley, Dorina Cadar, Claire J Steves, Kevin A Davies, Alan J Hakim, Nicholas Gall, Jessica A Eccles, Vicky Bowyer, Lisa Quadt, Nathan Cheetham

“…This association remained after sequential models adjusting for age, sex, ethnic group, education level and index of multiple deprivation (OR 1.33 (95% CI 1.10 to 1.61)) and further adjustment for vaccination status and number of vaccinations (OR 1.33 (95% CI 1.10 to 1.60)). …”
Get full text

Development of ¹¹¹In-Labeled Monoclonal Antibodies Targeting SFTSV Structural Proteins for Molecular Imaging of SFTS Infectious Diseases by SPECT by Takeshi Fuchigami, Mya Myat Ngwe Tun, Yusuke Tanahara, Kodai Nishi, Sakura Yoshida, Kazuma Ogawa, Morio Nakayama, Daisuke Hayasaka

“…No effective vaccines or treatments are currently available for severe fever with thrombocytopenia syndrome (SFTS), a fatal tick-borne infectious disease caused by the SFTS virus (SFTSV). …”
Get full text

A phase I, randomized, placebo‐controlled trial to evaluate the pharmacokinetics, safety, and tolerability of nirsevimab in healthy Chinese adults by Xiaomeng Mao, Xiaohan Hua, Chengyi Wu, Xiaoyun Ge, Jie Zhang, Xiaojie Wu, Robert J. Kubiak, Ulrika Wählby Hamrén, Tonya Villafana, Georgios Christou, Jannine Green, Therese Takas, Yuwen Jin

Get full text

The evolving landscape of COVID-19: factors associated with in-hospital COVID-19 related mortality during the 2023–2024 phase of JN.1 subvariant dominance by Drieda Zaçe, Albiana Çekrezi, Christopher Jones, Ludovica Ferrari, Giuseppe De Simone, Elisabetta Teti, Vincenzo Malagnino, Marco Iannetta, Loredana Sarmati, Anna Maria Geretti

“…It is imperative to advocate for up-to-date COVID-19 vaccination among older people and other vulnerable groups.…”
Get full text

Risk factors for disease progression and clinical outcomes in patients with COVID-19 in Taiwan: a nationwide population-based cohort study by Raymond N. Kuo, Wanchi Chen, Wen-Yi Shau

“…Adjusting for age, sex, region, risk factors, and vaccination status, elderly patients had higher risks of hospital admission, ICU admission, invasive ventilatory support, fatal outcome, and composite outcome. …”
Get full text

Clinical outcomes of early remdesivir administration in hospitalized patients at high risk for severe COVID-19 during the Omicron wave by Yeon Ju La, Won Sup Oh, Changhyup Kim, Myoung-nam Lim, Yong Duk Jeon

“…Additionally, BMI (OR, 0.908; 95% CI, 0.824, 1.000; P = 0.049) and vaccination with more than three doses (OR, 0.412; 95% CI, 0.202, 0.839; P = 0.015) were independent factors associated with the need for oxygen supply. …”
Get full text

Inequalities in health behaviours during the COVID-19 pandemic – a commentary by Aleksandra Herbeć

“…The focus of the pandemic response has been on health protective behaviours (e.g. update of vaccinations, isolation, and use of face covering). Health behaviours and health behaviour change (such as changes in physical activity, diet and alcohol consumption) have been socio-demographically- patterned already before the COVID-19 pandemic. …”
Get full text

Patent Foramen Ovale and Closure Technique with the Amplatzer Occluder by Bernhard Meier

“…It represents thus a kind of mechanical vaccination.…”
Get full text

The power of health economics and outcomes research (HEOR) in making decisions that matter by Oscar Herrera Restrepo

“… Deciding on approving and granting market access to new medical technologies such as pharmaceutical products, vaccines, or medical devices is a multifactorial research problem. …”
Get full text

The power of health economics and outcomes research (HEOR) in making decisions that matter by Oscar Herrera Restrepo

“… Deciding on approving and granting market access to new medical technologies such as pharmaceutical products, vaccines, or medical devices is a multifactorial research problem. …”
Get full text

Seeding Stress Resilience through Inoculation by Archana Ashokan, Meenalochani Sivasubramanian, Rupshi Mitra

“…This articulation has been referred to as “stress inoculation,” reminiscent of resilience to the pathology generated through vaccination by attenuated pathogen itself. Using experimental evidence from animal models, this review explores relationship between nature of the “inoculum” stress and subsequent psychological resilience.…”
Get full text

Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53 by Iulianna C. Taritsa, Eric T. Fossel

“…These agents can broadly be classified into six categories: the viral approach, direct modifiers of the p53 pathway, epigenetic modifiers of the p53 pathway, synthetic lethal agents, structural reactivators, and immune activating vaccines. Even these strategies have been met with limited success. …”
Get full text

Some statements on medical care in the "new normal" post-covid-19 by Alfredo Darío Espinosa Brito

“…This has been possible thanks to the joint efforts of the whole of society, with its highest authorities ahead, the capacity and dedication of health professionals organized in a vigorous national health system, obtaining and applying effective native drugs and the massive immunization against SARS-COV-2, with our Cuban Abdala and Soberanas vaccines. Comments are made on a group of lessons learned during the pandemic, on the existence of many doubts and questions still unanswered, on the new risks -especially for the most vulnerable- including the so-called post-COVID syndrome, when events are held more massive outbreaks of different kinds, as well as alerting to the frequent appearance of new coronavirus’ variants and recent "waves" of patients in different countries. …”
Get full text

Global burden of five major types of gastrointestinal cancer by Arjun Singh

“…Key priorities include vaccination, reducing modifiable risks, improving screening, expanding care access, and advancing prevention/therapy research. …”
Get full text

Sickness, Hygienic Education and Village Practice: Tuberculosis in the Life of a Cobbler by Tuija Saarinen

“…The first concord of antibiotics was received in 1947. Vaccinations against tuberculosis started on a mass scale in the following year. …”
Get full text

First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India by Aniruddha Jakharia, Biswajyoti Borkakoty, Sumi Pait, Gautam Baruah, Rahul Hazarika, Dipankar Biswas

“…Virus isolation is of paramount importance for development of vaccines, in-vitro screening of antiviral compounds, pathogenesis studies, etc., Many cell lines were studied for amplification and replication of SARS-CoV-2 and Vero cells were found to be ideal cell lines for isolation. …”
Get full text

Enhanced Immunogenicity and Affinity with A35R-Fc-Based Chimeric Protein Compared to MPXV A35R Protein by Shimeng Bai, Yanxin Cui, Qibin Liao, Hongyang Yi, Zhonghui Liao, Gengwei Zhang, Fenfang Wu, Hongzhou Lu

“…These results support the potential of Fc domain chimeric antigens as a strategy to enhance the efficacy of subunit vaccines targeting the MPXV.…”
Get full text

Continuous detection of Chikungunya Virus in a passive surveillance system in southern Thailand, 2012-2019. by Aaron Farmer, Kathryn B Anderson, Darunee Buddhari, Thanaporn Hortiwakul, Boonsri Charernmak, Butsaya Thaisomboonsuk, Tippa Wongstitwilairoong, Taweewun Hunsawong, Chonticha Klungthong, Piyawan Chinnawirotpisan, Sarunyou Chusri, Stefan Fernandez

“…Chikungunya virus (CHIKV) infections are distributed across the globe, causing significant and, often, lasting morbidity. CHIKV vaccines are in development, but their evaluation is limited by the unpredictability of CHIKV transmission, which classically manifests as explosive epidemics separated by variable interepidemic periods. …”
Get full text

Recurrent Herpetic Stromal Keratitis in Mice: A Model for Studying Human HSK by Patrick M. Stuart, Tammie L. Keadle

“…We will document both differences and similarities that derive from this fundamental difference in these models with an eye towards possible vaccines and therapies that demonstrate promise in treating HSK.…”
Get full text

The power of health economics and outcomes research (HEOR) in making decisions that matter by Oscar Herrera Restrepo

“… Deciding on approving and granting market access to new medical technologies such as pharmaceutical products, vaccines, or medical devices is a multifactorial research problem. …”
Get full text