Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…In this study, we employed an immunoinformatic strategy to design a set of candidate multi-epitope subunit vaccines by combining the most potent B and T cell epitopes from three targeted antigenic proteins (BabA, CagA, and VacA). Out of the 12 hypothetical vaccines generated, two (HP_VaX_V1 and HP_VaX_V2) were found to be strongly immunogenic, non-allergenic, and structurally stable. …”
Get full text

Successful Non-Surgical Root Canal Treatment on Auto-Transplanted Maxillary Premolar with Apical Periodontitis by Christopher M. Naglieri, Ellie Bash, Glen A. Karunanayake, Carlos H. R. Camargo, Takashi Komabayashi

“…The canal was cleaned and shaped to a size #80 using copious irrigation of 2.5% sodium hypochlorite (NaOCl), followed by 17% ethylenediaminetetraacetic acid (EDTA) via the EndoVac Negative Pressure Irrigation system. The tooth was dried with paper points, and then calcium hydroxide was mixed with 2.5% NaOCl and placed with an amalgam carrier 2 mm from the radiographic apex. …”
Get full text

Inkjet-printed electronics for rapid and low-cost prototyping of digital microfluidic devices using an off-the-shelf printer by Babak Kamali Doust Azad, Amirhossein Roozbahani, Seyed Mohammad Tabatabaei, Amirali Valinejad, Alireza Fazelian, Kimia Shahmoradi, Fatemeh Khatami, Seyed Mohammad Kazem Aghamir, Mohammadreza Kolahdouz

“…Functional DMF chips are fabricated using tape, parafilm, and SU8 as dielectric and silicone oil as the hydrophobic layers, enabling actuation voltages as low as 144 VDC and 92 VAC@100 kHz for a whole-blood droplet. We detail our actuation and control circuitry, designed entirely with standard electronic modules and components. …”
Get full text

Continuous tunability of refractive index contrast in LiNbO3 optical waveguides fabricated by high-vacuum vapor-phase proton exchange by Mihnea Raoul Sandu, Alicia Petronela Rambu, Laura Hrostea, Sorin Tascu

“…This paper presents a simple and reliable method allowing well-controlled index contrast tunability between high-index contrast (Δn e  = 0.1) and low-index contrast (Δn e  = 0.035) while benefiting from the optical nonlinearity of LiNbO3 waveguides fabricated using HiVac-VPE technique. The study involves both planar and channel lithium niobate waveguides. …”
Get full text

Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin by Togbemabou Primous Martial Godjedo, Alidehou Jerrold Agbankpe, Moussiliou Noël Paraiso, Tamegnon Victorien Dougnon, Marie Hidjo, Lamine Baba-Moussa, Honore Bankole

“…The results of this study showed that there is an emergence of cases of meningococcal of serogroup C four years after the introduction of MenAfricVac in Benin. These results demonstrated the effectiveness of case-by-case surveillance in detecting small changes in the distribution of serogroups that could have important implications for public health strategies in the coming seasons.…”
Get full text

The association between violence victimization and subsequent unplanned pregnancy among adolescent girls in Uganda: Do primary schools make a difference? by Katherine G Merrill, Louise Knight, Janet Nakuti, Angel Mirembe, Elizabeth Allen, Amiya Bhatia, Jenny Parkes, Dipak Naker, Karen M Devries

“…We analyzed data from the Contexts of Violence in Adolescence Cohort (CoVAC) study in Luwero District, Uganda. Primary students in 42 schools completed surveys in 2014 (Wave 1) and 2018 (Wave 2). …”
Get full text

Factors associated with the formation of neutralizing antibodies post-vaccination: a lesson from COVID-19 vaccination by Hana Ratnawati, Fen Tih, Grace Puspasari, Allen A. Pelapelapon, Steven Felim

“…Methods: A cross-sectional study was conducted among mass vaccination attendees using inactivated CoronaVac. Collected the peripheral blood serum four weeks following the second vaccine dose. …”
Get full text

COMBINED TREATMENT OF LOCALLY-ADVANCED BLADDER CANCER by I. V. Chernyshev, Y. V. Samsonov, D. V. Perepechin, A. M. Ulbashev

“…An important component of treatment has been the use of platinum (cisplatin or carboplatin) in Schemes M–VAC and GP. An objective response is possible in 44.7%, and the stabilization process in 40.4% of patients.Results. …”
Get full text

Prevalence of Helicobacter pylori infection in the general population in Wuzhou, China: a cross-sectional study by Liumei Yan, Qiliang He, Xinyun Peng, Sen Lin, Meigu Sha, Shujian Zhao, Dewang Huang, Jiemei Ye

“…Results Serum Ure, CagA, and VacA antibodies were detected in 43.3%, 27.4%, and 23.6% of the 22,769 subjects that were screened, respectively. …”
Get full text

OUR EXPERIENCE IN TREATMENT OF ENTEROATMOSPHERIC FISTULAS FORMED AS A RESULT OF MINE-EXPLOSIVE INJURY by Kyrylo Parkhomenko, Anastasia Drozdova, Kostiantyn Prokopenko, Ivan Parkhomenko

“…The second stage is the delimitation of the intestinal fistula with one's tissues or with the help of various "fistula adapters". Next, VAC bandages were installed for active drainage. …”
Get full text

Pivotal role of Helicobacter pylori virulence genes in pathogenicity and vaccine development by Ayman Elbehiry, Eman Marzouk, Adil Abalkhail, Wael Sindi, Yasir Alzahrani, Salem Alhifani, Turki Alshehri, Nuha Abdulaziz Anajirih, Turki ALMutairi, Ahmad Alsaedi, Feras Alzaben, Abdullah Alqrni, Abdelmaged Draz, Abdulaziz M. Almuzaini, Sahar N. Aljarallah, Abdulrahman Almujaidel, Akram Abu-Okail

“…This review discusses various virulence factors associated with H. pylori, such as cytotoxin-associated gene A (cagA), vacuolating cytotoxin gene (vacA), outer membrane proteins (OMPs), neutrophil-activated protein (NAP), urease (ure), and catalase. …”
Get full text

مقایسه تمرینات اصلاحی با تمرینات ایکس‌باکس کینکت بر تعادل ایستا و پویا در دختران نوجوان دارای ناهنجاری کف پای صاف... by فریده هوشمند فر, احمد ابراهیمی عطری, بهناز شاه طهماسبی, شهناز بمبئی‌چی

“…قبل و بعد از تمرینات اصلاحی و تمرینات ایکس‌باکس کینکت، تعادل ایستا و پویا آزمودنی‌ها با دستگاه بایودکس مدل Balance SD, System115, VAC اندازه‌گیری شد. بمنظور تجزیه و تحلیل داده‌ها در این پژوهش، نرم افزار آماری spss نسخه ۲۱ استفاده شد و از آزمون آنالیز واریانس با اندازه‌گیری مکرر جهت بررسی تغییرات درون گروهی ‌(پیش‌آزمون و پس‌آزمون) و بین گروهی، استفاده شد. …”
Get full text

Sustainable aquaculture and sea ranching with the use of vaccines: a review by Alma Alfatat, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Jia Cai, Jia Cai, Jia Cai, Jia Cai, Jia Cai, Yu Huang, Yu Huang, Yu Huang, Yu Huang, Yu Huang, Muhammad Fachri, Hagai Nsobi Lauden, Shaoliang Lyu, Xuefeng Wang, Sahya Maulu, Berchie Asiedu, Syaifiuddin Syaifiuddin

“…Innovations like the recombinant DNA vaccine for goldfish using the G protein expressed by baculovirus for spring viremia for carp and the ME-VAC Aqua Strept vaccine for tilapia highlight their ability to reduce antibiotic dependence and support greener practices. …”
Get full text

Pre-existing IgG antibodies to HCoVs NL63 and OC43 Spike increased during the pandemic and after COVID-19 vaccination by Zahra Hasan, Kiran Iqbal Masood, Marc Veldhoen, Shama Qaiser, Marta Alenquer, Mishgan Akhtar, Sadaf Balouch, Junaid Iqbal, Yaqub Wassan, Shahneel Hussain, Khalid Feroz, Sajid Muhammad, Atif Habib, Akbar Kanji, Erum Khan, Afsar Ali Mian, Rabia Hussain, Maria Joao Amorim, Zulfiqar A. Bhutta

“…IgG antibody levels increased during the pandemic; 2.7-fold to HCoV-NL63 and 1.9-fold to HCoV-OC43.SinoVac and BNT162b2 vaccine induced an increase in IgG antibodies to Spike SARS-CoV-2 as well as HCoV-NL63 and HCoV-OC43.Our data show that antibodies to spike protein of endemic coronaviruses were present in the prepandemic population. …”
Get full text

Longitudinal immunogenicity cohort study of SARS-CoV-2 mRNA vaccines across individuals with different immunocompromising conditions: heterogeneity in the immune response and cruci... by Annalisa Ciabattini, Elena Pettini, Fabio Fiorino, Jacopo Polvere, Simone Lucchesi, Chiara Coppola, Simone Costagli, Gabiria Pastore, Anna Sicuranza, Monica Tozzi, Arianna Lippi, Francesca Panza, Monica Bocchia, Alessandro Bucalossi, Guido Garosi, David Bennett, Sonia Bernazzali, Massimiliano Fabbiani, Francesca Montagnani, Donata Medaglini

“…Here, we determined and compared in a longitudinal study the immune response elicited by SARS-CoV-2 vaccination across different groups of individuals who are immunocompromised. Methods: In the PatoVac_COV longitudinal prospective single-centre study, the spike-specific B cell and antibody responses to SARS-CoV-2 mRNA vaccination were compared across 5 different groups of individuals with haematological malignancies, hematopoietic stem cell (HCT) or solid organ transplantation (SOT), undergoing haemodialysis, and people living with HIV (PLWH), for a total of 585 participants. …”
Get full text

Nanostructured lipid carriers based mRNA vaccine leads to a T cell–inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a... by Carole Fournier, Marion Mercey-Ressejac, Valentin Derangère, Amal Al Kadi, David Rageot, Christine Charrat, Alexis Leroy, Julien Vollaire, Véronique Josserand, Marie Escudé, Séverine Escaich, François Ghiringhelli, Thomas Decaens, Fabrice P. Navarro, Evelyne Jouvin-Marche, Patrice N. Marche

“…Funding: This work was supported by Inserm Transfert, la Région Auvergne Rhône Alpes, FINOVI, and the French Ministry of Higher Education, research and innovation (LipiVAC, COROL project, funding reference N° 2102992411).…”
Get full text

Identification and subcellular localization of proteins that interact with Duck plague virus pUL14 in infected host cells by Jieyu Wan, Mingshu Wang, Anchun Cheng, Wei Zhang, Qiao Yang, Bin Tian, Xumin Ou, Di Sun, Yu He, Xinxin Zhao, Ying Wu, Shaqiu Zhang, Juan Huang, Zhen Wu, YanLing Yu, Ling Zhang, Dekang Zhu, Renyong Jia, Mafeng Liu, Shun Chen

Get full text