Effect of Genicular Nerve Block (GNB) on Pain in Lesions of the Knee Joint: A Meta-Analysis of Randomized Controlled Trials by Li W, Xu F, Chen F, Cao L, Bao X

“…Weiming Li,1,* Fenglian Xu,2,* Feng Chen,1 Lei Cao,1 Xiaohang Bao1 1Department of Anesthesiology, second Affiliated Hospital of Army Medical University, Chongqing, 400037, People’s Republic of China; 2Gynaecology and Obstetrics, second Affiliated Hospital of Army Medical University, Chongqing, 400037, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaohang Bao, Department of Anesthesiology, second Affiliated Hospital of Army Medical University, Chongqing, 400037, People’s Republic of China, Tel +13708328111, Email 6851950@qq.comAbstract: To explore the effect of genicular nerve block (GNB) on pain in lesions of the knee joint. …”
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Golden Tandem of Photothermal Ablation and Simultaneous Anti-Inflammation in One Nanoparticle for Activated Macrophage-Targeted Atherosclerosis Treatment by Lu Y, Wang Y, Li Y, Li Y, Jiang YW, Li J

“…Yuqing Lu,1,* Yan Wang,2,* Yize Li,1,* Yunan Li,1 Yao-Wen Jiang,1,3 Jingjing Li1,3 1School of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, People’s Republic of China; 2The First Clinical Medical College, Xuzhou Medical University, Xuzhou, 221004, People’s Republic of China; 3Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yao-Wen Jiang; Jingjing Li, Email jiang@xzhmu.edu.cn; qingchao0124@163.comIntroduction: Photothermal therapy (PTT) is attracting increasing attention in treating atherosclerotic plaques. …”
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Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients by Peizeng Jia, Jianyin Zou, Shankai Yin, Feng Chen, Hongliang Yi, Qian Zhang

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Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms by Xiao Wang, Wenxuan Shi, Yu Jin, Zhuoyuan Li, Tanjun Deng, Tingshu Su, Ao Zheng, Lingyan Cao

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Symptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study by Yu C, Xu M, Pang X, Zhang Y, Cao X, Xu Y, Huang S, Zhao H, Chen C

“…Chunchun Yu,1 Mengying Xu,1 Xinyue Pang,2 Yuting Zhang,3 Xinmei Cao,2 Yixin Xu,1 Shuai Huang,1 Hongjun Zhao,4 Chengshui Chen1,3,4 1Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 2Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 3Cixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, Zhejiang, 315302, People’s Republic of China; 4Zhejiang Province Engineering Research Center for Endoscope Instruments and Technology Development, Department of Pulmonary and Critical Care Medicine, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, People’s Republic of ChinaCorrespondence: Hongjun Zhao; Chengshui Chen, Zhejiang Province Engineering Research Center for Endoscope Instruments and Technology Development, Department of Pulmonary and Critical Care Medicine, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, People’s Republic of China, Email zhaohongjun@wmu.edu.cn; chenchengshui@wmu.edu.cnPurpose: This study aims to construct a contemporaneous symptom network of inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease (ECOPD) based on the symptom cluster, identify core and bridge symptoms, and patient subgroups with different symptom clusters based on individual differences in the intensity of patient symptom experiences.Patients and Methods: This study used convenience sampling to collect demographic, symptom, auxiliary examination, and prognosis information of 208 inpatients with ECOPD from April 2022 to October 2023. …”
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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…Yinshuang Zou,1– 3,* Yaji Yang,1,3,* Jianye Yang,1,3 Yanhao Zhang,4 Chen Zhao,1,3 Leilei Qin,1,3 Ning Hu1,3 1Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Orthopedics, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, 434000, People’s Republic of China; 3Laboratory of Orthopedics, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Army Medical University, Chongqing, 400038, People’s Republic of China*These authors contributed equally to this workCorrespondence: Leilei Qin; Ning Hu, Email qinleilei@stu.cqmu.edu.cn; huning@cqmu.edu.cnBackground: Diagnosing chronic periprosthetic joint infection (PJI) is challenging. …”
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Risk factors and early prediction of cardiorenal syndrome type 3 among acute kidney injury patients: a cohort study by Hui Lin, Xiaoyu Guo, Mengzhu Wang, Xiaole Su, Xi Qiao

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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Hui Liu,1,* Siyun Liu,1,* Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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The Timing and Spectral Properties of the 2022 Outburst of SGR J1935+2154 Observed with NICER by Fu Yu-Cong, Lin Lin, Ge Ming-Yu, Enoto Teruaki, Hu Chin-Ping, Younes George, Göǧüş Ersin, Malacaria Christian

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Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis by Huang L, Zhang T, Zhu Y, Lai X, Tao H, Xing Y, Li Z

“…Li Huang,1– 3,* Tong Zhang,4,* Yuanyuan Zhu,5 Xueling Lai,6 Hualin Tao,1– 3 Yuhan Xing,5 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, Sichuan, People’s Republic of China; 3Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, Sichuan, People’s Republic of China; 4Department of Laboratory Medicine, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 5School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, People’s Republic of China; 6Shenzhen Guangming Maternal & Child Healthcare Hospital, Shenzhen, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaoyinqian Li, Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, Sichuan, 646000, People’s Republic of China, Email lizhaoyinqian@swmu.edu.cn Yuhan Xing, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, People’s Republic of China, Email xingyh8@mail.sysu.edu.cnAbstract: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications which exerts detrimental effects on mothers and children. …”
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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling by Xian Jin, Liang Liu, Yaping Zhang, Yin Xiang, Guizhi Yin, Yi Lu, Ludong Shi, Jian Dong, Chengxing Shen

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ATF3 Knockdown Exacerbates Astrocyte Activation by Inhibiting Phosphorylation of Drp1 in Ischemic Stroke by Huang R, Huang X, Yang H, Wu H, Liu F, Saw PE, Cao M

“…Rong Huang,1 Xiaoyan Huang,1 Hongmei Yang,1 Haixuan Wu,1 Fan Liu,1 Phei Er Saw,2,3 Minghui Cao1,4 1Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, People’s Republic of China; 2Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, People’s Republic of China; 3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, People’s Republic of China; 4Department of Anesthesiology, Shenshan Medical Center, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Shanwei, 516600, People’s Republic of ChinaCorrespondence: Phei Er Saw; Minghui Cao, Email caipeie@mail.sysu.edu.cn; caomh@mail.sysu.edu.cnIntroduction: ATF3, a stress-induced transcription factor, has been implicated in the injury processes of various cell types, including neurons. …”
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Global Research Trends and Focus on the Link Between Heart Failure and NLRP3 Inflammasome: A Bibliometric Analysis From 2010 to 2024 by Lian Y, Zhang H, Xing W, Li S, Lai X, Jia S, Shang J, Liu H

“…YanJie Lian,1,2,* Heyi Zhang,1,2,* Wenlong Xing,1 Sinai Li,3 Xiaolei Lai,1 Sihan Jia,1 JuJu Shang,1 Hongxu Liu1 1Department of Cardiovascular, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China; 2Graduate School of Capital Medical University, Beijing, 100069, People’s Republic of China; 3Beijing Institute of Traditional Chinese Medicine, Beijing, 100010, People’s Republic of China*These authors contributed equally to this workCorrespondence: JuJu Shang, Department of cardiovascular, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China, Email shangjuju@bjzhongyi.com Hongxu Liu, Department of cardiovascular, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China, Email lhx_263.netBackground: Heart failure (HF) is characterized by elevated morbidity, mortality, and rehospitalization frequencies. …”
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Association between the atherogenic index of plasma and non-alcoholic fatty liver disease in Korean pregnant women: secondary analysis of a prospective cohort study by Rong Shuai, Yuxing He, Dongqian Yang, Yingying Zhang, Li Zhang

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Development and Evaluation of an ICU Nurse Training Program on Oral Mucosal Pressure Injury Prevention and Management Using the ADDIE Model by Jia T, Lan Y, Pang J, Ma M, Ding Z, Wang Y, Jiang E

“…Tiantian Jia,1 Yunxia Lan,2 Jing Pang,2 Mengdan Ma,1 Zhe Ding,3 Yongting Wang,1 Enshe Jiang4 1Cardiac Surgery Intensive Care Unit, The Affiliated Chest Hospital of Zhengzhou University, Zhengzhou, 450008, People’s Republic of China; 2Department of Nursing, The Affiliated Chest Hospital of Zhengzhou University, Zhengzhou, 450008, People’s Republic of China; 3Department of Rehabilitation, The Affiliated Chest Hospital of Zhengzhou University, Zhengzhou, 450008, People’s Republic of China; 4Institute of Nursing and Health, Henan University, Kaifeng, 475004, People’s Republic of ChinaCorrespondence: Enshe Jiang, Institute of Nursing and Health, Henan University, No. 1 Jinming Road, Kaifeng, Henan, 475004, People’s Republic of China, Email esjiang@gmail.com Yongting Wang, Cardiac Surgery Intensive Care Unit, the Affiliated Chest Hospital of Zhengzhou University, No. 1 Weiwu Road, Zhengzhou, Henan, 450008, People’s Republic of China, Email 2313992171@qq.comPurpose: To construct a training course program for ICU nurses to care for oral mucosal membrane pressure injury (MMPI) and evaluate its implementation effects based on the ADDIE model.Patients and Methods: A research team was established to construct the training course program in January 2024. …”
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FEASTS: Radial Distribution of H i Surface Densities Down to 0.01 M⊙ pc−2 of 35 Nearby Galaxies by Jing Wang, Dong Yang, Xuchen Lin, Qifeng Huang, Zhijie Qu, Hsiao-wen Chen, Hong Guo, Luis C. Ho, Peng Jiang, Zezhong Liang, Céline Péroux, Lister Staveley-Smith, Simon Weng

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Safety and efficacy of low-dose esketamine weakly opioidized anesthesia in elderly patients with lumbar spinal stenosis undergoing surgery: a prospective, double-blind randomized c... by Ni-Na Hou, Meng-Yun Zhang, Yu-Wei Zhang, Hong-Jing Wu, Hong Luo, Heng Yang

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Association Between Diurnal Temperature Range and Risk of Cardiomyopathy-Induced Hospitalisation in Henan, China: A Time-Series Study by Zhang Z, Wang Y, Zhou Y, Pei J, Zhao G, Dong P, Yang K, Liu H, Xie N, Li X, Zang X, Lin F, Chen Z

“…Zhaolin Zhang,1,* Yongbin Wang,2,* Yifeng Zhou,1 Jiachao Pei,1 Guoan Zhao,1,3 Pingshuan Dong,4 Kan Yang,5 Hui Liu,6 Na Xie,7 Xuefang Li,3 Xiayan Zang,3 Fei Lin,1,3 Zhigang Chen1 1Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 2Department of Epidemiology and Health Statistics, Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China; 3Henan Engineering Technology Research Center of Environmental Meteorological Medicine, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 4Department of Cardiology,The First Affiliated Hospital of Henan University of Science and Technology, Luoyan, 471000, People’s Republic of China; 5Department of Cardiology,Nanyang Central Hospital, Nanyang, 473005, People’s Republic of China; 6Department of Cardiology,Anyang District Hospital, Anyang, 455000, People’s Republic of China; 7Department of Cardiology,The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Lin; Zhigang Chen, Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui, Henan, People’s Republic of China, Tel +86 18567557937, Email 1fy2000129@xxmu.edu.cn; 1fy2015157@xxmu.edu.cnPurpose: The effect of the diurnal temperature range (DTR) on human health in diverse geographic areas and the potential confounding factors are not fully understood. …”
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Combination Fractional Carbon Dioxide Laser Treatment and Bone Marrow Mesenchymal Stem Cell Therapy Enhances the Treatment of Skin Photoaging in a Murine Model System by Li L, He Z, Yu C, Zhang C, Yu Y, Li Y, Xu X

“…Li Li,1– 3,* Zeyu He,3– 5,* Chengqian Yu,3– 5 Chao Zhang,3– 5 Yanqiu Yu,6 Yuanhong Li,3– 5 Xuegang Xu3– 5 1ShanXi Medical University, Taiyuan, People’s Republic of China; 2Department of Dermatology, The First Hospital of ShanXi Medical University, Taiyuan, 030001, People’s Republic of China; 3Department of Dermatology, The First Hospital of China Medical University, Shenyang, 030001, People’s Republic of China; 4Key Laboratory of Immunodermatology (China Medical University), Ministry of Education, Shenyang, 110001, People’s Republic of China; 5NHC Key Laboratory of Immunodermatology (China Medical University), Shenyang, 110001, People’s Republic of China; 6Department of Pathophysiology, College of Basic Medical Science, China Medical University, Shenyang, 110122, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuegang Xu, Department of Dermatology, The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang, Liaoning Province, 110001, People’s Republic of China, Email xuxuegang2749290@163.com Li Li, Department of Dermatology, The First Hospital of ShanXi Medical University, No. 85 South Jiefang Road, Yingze District, Taiyuan, Shanxi Province, 030001, People’s Republic of China, Email lilizaimu0807@163.comBackground: Fractional carbon dioxide lasers and bone marrow mesenchymal stem cells (BMSCs) are commonly employed in the treatment of skin photoaging.Objective: This study was developed to explore the effects of combination carbon dioxide laser treatment and BMSC injection on skin photoaging and the underlying molecular mechanisms.Methods & Materials: In total, 24 mice with experimentally photoaged skin were separated into control, carbon dioxide fractional laser treatment, combination therapy, and BMSC injection groups. …”
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Solar Modulation of Low-energy Cosmic-Ray Nitrogen and Its Comparison with Oxygen by Yun Li, Xiaoping Zhang, Shuai Fu, Zhenning Shen, Yi Xu, Haoyu Lu, Jinbin Cao, Tianle Zhu

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