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    Exploring the Causal Relationship Between Frailty and Chronic Obstructive Pulmonary Disease: Insights From Bidirectional Mendelian Randomization and Mediation Analysis by Cheng Z, Wu J, Xu C, Yan X

    Published 2025-01-01
    “…Zewen Cheng,1 Jian Wu,1 Chun Xu,2 Xiaokun Yan1 1Department of Thoracic Surgery, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou, Jiangsu, 215000, People’s Republic of China; 2Department of Cardio-Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215000, People’s Republic of ChinaCorrespondence: Xiaokun Yan, Department of Thoracic Surgery, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou, Jiangsu, 215000, People’s Republic of China, Email yanxk2008@126.comBackground: Observational studies have underscored a robust association between frailty and chronic obstructive pulmonary disease (COPD), yet the causality remains equivocal.Methods: This study employed bidirectional two-sample Mendelian randomization (MR) analysis. …”
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    ETHICS OF LIABILITY K.-O.APELY IN THE LANDSCAPES OF CONTRACTUALISM by Dmytro V. Usov

    Published 2015-05-01
    “…It is consistently proved that in the context of substantial interest of justification was established the algorithms of universal values of modern philosophical anthropology, which will become the core of Apel’s responsible person. …”
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