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    Asthma Biologics Across the T2 Spectrum of Inflammation in Severe Asthma: Biomarkers and Mechanism of Action by Lindsley AW, Lugogo N, Reeh KAG, Spahn J, Parnes JR

    Published 2025-01-01
    “…Andrew W Lindsley,1 Njira Lugogo,2 Kaitlin AG Reeh,3 Joseph Spahn,3 Jane R Parnes1 1Amgen Inc., Thousand Oaks, CA, USA; 2Michigan Medicine Asthma Program, University of Michigan, Ann Arbor, MI, USA; 3AstraZeneca, Gaithersburg, MD, USACorrespondence: Andrew W Lindsley, US Medical Affairs, Amgen Inc., One Amgen Center Dr, Thousand Oaks, CA, 91320, USA, Email alindsle@amgen.comAbstract: Airway inflammation, a hallmark feature of asthma, drives many canonical features of the disease, including airflow limitation, mucus plugging, airway remodeling, and hyperresponsiveness. …”
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    Association of race and ethnicity with mortality in adults with SLE: a systematic literature review and meta-analysis by Sam Norton, Chris Wincup, Patrick Gordon, Kate Bramham, James Galloway, Zijing Yang, Samir Patel, Maryam Adas, Deepak Nagra, Mark Russell

    Published 2025-02-01
    “…We observed no significant association in the mortality of Black patients compared with White patients from non-USA cohorts, but a scarcity of data outside of the USA was highlighted. …”
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    Validation of Mortality Data Sources Compared to the National Death Index in the Healthcare Integrated Research Database by Jamal-Allial A, Sponholtz T, Vojjala SK, Paullin M, Papazian A, Eshete B, Mahmoudpour SH, Verpillat P, Beachler DC

    Published 2025-02-01
    “…Aziza Jamal-Allial,1 Todd Sponholtz,1 Shiva K Vojjala,2 Mark Paullin,2 Anahit Papazian,1 Biruk Eshete,2 Seyed Hamidreza Mahmoudpour,3 Patrice Verpillat,3 Daniel C Beachler2 1Safety & Epidemiology, Carelon Research, Newton, MA, USA; 2Safety & Epidemiology, Carelon Research, Wilmington, DE, USA; 3Merck Healthcare KGaA, Darmstadt, GermanyCorrespondence: Daniel C Beachler, Carelon Research, 123 Justison Street, Suite 200, Wilmington, DE, 19801, USA, Email Daniel.beachler@carelon.comBackground: The National Death Index (NDI) is the gold standard for mortality data in the United States (US) but has a time lag and can be operationally intensive. …”
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