Development of a genetically tailored implantation hepatocellular carcinoma model in Oncopigs by somatic cell CRISPR editing by Lobna Elkhadragy, Maximillian J. Carlino, Luke R. Jordan, Thomas Pennix, Nahed Ismail, Grace Guzman, Jonathan P. Samuelson, Lawrence B. Schook, Kyle M. Schachtschneider, Ron C. Gaba

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Multidisciplinary clinic model enhances liver and metabolic health outcomes in adults with MASH by Jonathan G. Stine, David Bradley, Jennifer McCall-Hosenfeld, Victoria Motz-Patel, Justin Tondt, Sarah Batra, Britney Fitzgerald, Samantha Garcia, Breianna Hummer, Courtney Kindrew, Autumn Koppenhaver, Hannah Mohr, Nataliya Smith, Heather Tressler, Kyra VanKirk, Karen Krok, Ian Schreibman, Elizabeth Stonesifer, Kofi Clarke

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Accelerating TB regimen development: introducing FAST-TB by T. Devezin, C. Chisholm, F. Jones, K. Lacourciere, B. Laughon, L. Ramachandra, A. Vernon, L. Zhang, P. Kim, C. Lienhardt

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Evolving concepts in intracranial pressure monitoring - from traditional monitoring to precision medicine by Rohan Mathur, Lin Cheng, Josiah Lim, Tej D. Azad, Peter Dziedzic, Eleanor Belkin, Ivanna Joseph, Bhagyashri Bhende, Sudha Yellapantula, Niteesh Potu, Austen Lefebvre, Vishank Shah, Susanne Muehlschlegel, Julian Bosel, Tamas Budavari, Jose I. Suarez

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Cartridge-based sequencing for bedaquiline resistance detection from sputum by J.D. Limberis, R.J. Nagel, D. Block, R.E. Colman, A. Nalyvayko, Z. Howard, S. Dewell, S. Chakravorty, J.Z. Metcalfe

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The American Society of Pain and Neuroscience (ASPN) Guidelines and Consensus on the Definition, Current Evidence, Clinical Use and Future Applications for Physiologic Closed-Loop... by Pope JE, Deer TR, Sayed D, Antony AB, Bhandal HS, Calodney AK, Chakravarthy K, Costandi S, Diep J, Durbhakula S, Fishman MA, Gilligan C, Goree JH, Guirguis M, Hagedorn JM, Hunter CW, Kallewaard JW, Kapural L, Lam CM, Li S, Mayrsohn B, Nijhuis H, Nikolic S, Petersen EA, Poree LR, Puri SK, Reece DE, Rosen SM, Russo MA, Shah JM, Staats PS, Verrills P, Vu CM, Levy RM, Mekhail N

“…Jason E Pope,1 Timothy Ray Deer,2 Dawood Sayed,3 Ajay B Antony,4 Harjot Singh Bhandal,1 Aaron K Calodney,5 Krishnan Chakravarthy,6 Shrif Costandi,7 Jack Diep,8 Shravani Durbhakula,9 Michael A Fishman,10 Christopher Gilligan,11 Johnathan Heck Goree,12 Maged Guirguis,13 Jonathan Michael Hagedorn,14 Corey William Hunter,15,16 Jan Willem Kallewaard,17,18 Leonardo Kapural,19– 21 Christopher M Lam,3 Sean Li,22 Brian Mayrsohn,23,24 Harold Nijhuis,25 Serge Nikolic,26 Erika A Petersen,27 Lawrence Raymond Poree,28 Shawn K Puri,29 David E Reece,30 Steven Mark Rosen,31 Marc A Russo,32 Jay M Shah,33 Peter Sean Staats,34 Paul Verrills,35 Chau M Vu,1 Robert M Levy,36 Nagy Mekhail37 1Evolve Restorative Center, Santa Rosa, CA, USA; 2Pain Services, The Spine & Nerve Center of the Virginias, Charleston, WV, USA; 3Department of Anesthesiology and Pain Medicine, The University of Kansas Medical Center, Kansas City, KS, USA; 4The Orthopaedic Institute, Gainesville, FL, USA; 5Clinical Research, Precision Spine Care, Tyler, TX, USA; 6Anesthesiology and Pain Medicine, Solaris Research Institute, Wilmington, DE, USA; 7Pain Medicine, Cleveland Clinic, Cleveland, OH, USA; 8Nevada Pain Management, Las Vegas, NV, USA; 9Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA; 10Michael Fishman MD PLLC, Lebanon, PA, USA; 11Robert Wood Johnson University Hospital, New Brunswick, NJ, USA; 12Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 13Interventional Pain Management Department, Ochsner Health System, New Orleans, LA, USA; 14Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; 15Ainsworth Institute of Pain Management, New York City, NY, USA; 16Physical Medicine & Rehabilitation, Icahn School of Medicine at Mount Sinai Hospital, New York City, NY, USA; 17Amsterdam University Medical Centre, Amsterdam, The Netherlands; 18Rijnstate Hospital, Arnhem, The Netherlands; 19Carolinas Pain Institute, Winston Salem, NC, USA; 20Centers for Clinical Research, Winston Salem, NC, USA; 21Chronic Pain Research Institute, Winston Salem, NC, USA; 22National Spine and Pain Centers, Shrewsbury, NJ, USA; 23Interventional Pain Management, Maywell Health, Plainview, NY, USA; 24Interventional Pain Management, Maywell Health, New York City, NY, USA; 25Anesthesiology, St Antonius Hospital, Nieuwegein, Utrecht, The Netherlands; 26Pain Medicine and Neuromodulation, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK; 27Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 28Anesthesia- Division of Pain Medicine, University of California, San Francisco, CA, USA; 29Integrated Pain Associates, Killeen, TX, USA; 30Absolute Pain Management, Rockville, MD, USA; 31Delaware Valley Pain and Spine Institute, Trevose, PA, USA; 32School of Biomedical Sciences, University of Newcastle, Newcastle, NSW, Australia; 33Samwell Institute of Pain Management, Colonia, Livingston, and Englewood, NJ, USA; 34National Spine and Pain Centers, Atlantic Beach, FL, USA; 35Metropain, Melbourne, VIC, Australia; 36Neuromodulation: Technology at the Neural Interface, International Neuromodulation Society, Boca Raton, FL, USA; 37Evidence-Based Pain Management Research, Cleveland Clinic, Cleveland, OH, USACorrespondence: Timothy Ray Deer, The Spine and Nerve Center of the Virginias, 400 Court Street, Charleston, WV, 25304, USA, Tel +1 304 347 6141, Email doctdeer@aol.comIntroduction: Neuromodulation has been a staple of treatment for moderate-to-severe chronic refractory pain since the introduction of the first spinal cord stimulator by Norman Shealy in 1967. …”
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Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis by Phuong T.T. Nguyen, Mia Shiue, Nina Kuprasertkul, Pedro Costa-Pinheiro, Luke T. Izzo, Laura V. Pinheiro, Hayley A. Affronti, Gabriel Gugiu, Shivani Ghaisas, Joyce Y. Liu, Jordan C. Harris, Charles W. Bradley, John T. Seykora, Xiaolu Yang, Taku Kambayashi, Clementina Mesaros, Brian C. Capell, Kathryn E. Wellen

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Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties by Ming Cheng, Demitri de la Cruz, Adam V. Crain, Paula Espinoza, Carrie Ng, Zachary C. Elmore, Aravind Asokan, Casey A. Maguire

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gynecologic cancer by Anne Mills, Leisha A Emens, Mary L Disis, Kunle Odunsi, John B Liao, Tyler Curiel, Margaret Gatti-Mays, Amir Jazaeri, Emese Zsiros, Marcus O Butler, Jyoti Bajpai, Katherine C Kurnit, Haider Mahdi, Laura Doherty, Claire F Friedman, Melissa A Geller, Sarah F Adams, Shelley A Dodt, Veena S John

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Protocol for the generation of HLF+ HOXA+ human hematopoietic progenitor cells from pluripotent stem cells by Sherry Li Zheng, Jonas L. Fowler, Julie Y. Chen, Christopher Li, Elaine Lin, Alana T. Nguyen, Angela Chen, George Q. Daley, Lay Teng Ang, Kyle M. Loh

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Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists by Dong Li, Sarah K. Tasian, Gerald Wertheim, Susan R. Rheingold, Kathrin M. Bernt, Haley Newman, Luanne Wainwright, Donna M. Wilmoth, Brian Thiel, Lea F. Surrey, Elizabeth Margolskee, Vinodh Pillai, Minjie Luo, Michele E. Paessler, Stephen P. Hunger, Marilyn M. Li, Yiming Zhong

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Person-centred language for describing stratified approaches to TB treatment by M. Nash, A. Deluca, E. Lessem, N. West, L. McKenna, E.V. McConnell, K. Angami, R. Herrera, A. Makone, G.E. Velásquez, R.E. Chaisson, P.P.J. Phillips

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Interactive effects of social media use and puberty on resting-state cortical activity and mental health symptoms by Nathan M. Petro, Giorgia Picci, Lauren K. Webert, Mikki Schantell, Jake J. Son, Thomas W. Ward, Kellen M. McDonald, Cooper L. Livermore, Abraham D. Killanin, Danielle L. Rice, Grace C. Ende, Anna T. Coutant, Erica L. Steiner, Tony W. Wilson

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Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review by Laya Jalilian-Khave, Razi Kitaneh, Binah Baht Ysrayl, Anna Borelli, Melissa C. Funaro, Marc N. Potenza, Gustavo A. Angarita

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Ground-based Reconnaissance Observations of 21 Exoplanet Atmospheres with the Exoplanet Transmission Spectroscopy Imager by Ryan J. Oelkers, Luke M. Schmidt, Erika Cook, Mary Anne Limbach, D. L. DePoy, J. L. Marshall, Jimmy Ardoin, Mitchell Barry, Evan Batteas, Alexandra Boone, Brant Conway, Silvana Delgado Adrande, John D. Dixon, Enrique Gonzalez-Vega, Alexandra Guajardo, Landon Holcomb, Christian Lambert, Shravan Menon, Divya Mishra, Jacob Purcell, Zachary Reed, Nathan Sala, Noah Siebersma, Nhu Ngoc Ton, Raenessa M. L. Walker, Z. Franklin Wang, Kaitlin Webber

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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

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Case study: Stomach ulcers in the context of tricuspid atresia—“I can barely stomach it” by Thomas C. Varkey, Chloe-Marie Lee Roeder, Rachel Elizabeth Daum, Sajana Ravi, Emily C. Courtois, Kyle Simtion, Caitlyn Simtion, Cheney E. Merhavy, Zachary I. Merhavy, Teresa C. Frohman, Elliot M. Frohman, Christie Spann

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Glioblastoma drives protease-independent extracellular matrix invasion of microglia by Chia-Wen Chang, Ashwin Bale, Rohit Bhargava, Brendan A.C. Harley

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α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak by Phuong M. Le, Jeanne M. Quinn, Annette S. Flozak, Adam W. T. Steffeck, Che-Fan Huang, Cara J. Gottardi

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Comparison of peroral endoscopic myotomy, laparoscopic Heller myotomy, and pneumatic dilation for patients with achalasia: a United States national experience by Dushyant Singh Dahiya, Bhanu Siva Mohan Pinnam, Saurabh Chandan, Hassam Ali, Manesh Kumar Gangwani, Amir Humza Sohail, Dennis Yang, Amit Rastogi

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