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  1. 581

    TRUMP ve AVRUPA TRANSATLANTİK DÜZENDE KIRILMA by Çağatay Özdemir

    Published 2019-08-01
    Subjects: “…us…”
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    Association of expedited review programmes with postmarketing safety events of new drugs approved by the US food and drug administration between 2007 and 2017 by Bao Liu, Xingyue Zhu

    Published 2022-07-01
    “…Objective To explore the associations between the risks of postmarketing safety events of new drugs and the four expedited programmes of priority review, accelerated approval, fast track and breakthrough therapy established by the US Food and Drug Administration (FDA); and to investigate whether multiple uses of expedited programmes, and the combinations of expedited programmes with orphan designation, were relevant to different safety profiles.Design Cohort study.Setting USA.Participants All new drugs approved by the FDA between 1 January 2007 and 31 December 2017, followed up until 10 April 2021.Outcome measures Safety events included safety-related withdrawal, new boxed warning, drug safety communication, postapproval risk evaluation mitigation strategy and safety-related labelling changes. …”
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    Association of daily step counts and step intensity with mortality among US adults: a cross–sectional study of NHANES 2005–2006 by Tianzhou Peng, Changhao Liu, Ti Yang, Leyi Liao, Qingping Li, Hanbiao Liang, Jiapeng Zhang, Chen Xie, Kai Wang, Chuanjiang Li

    Published 2025-01-01
    “…Abstract Background & aims We aimed to describe the dose–response relationship between daily step counts and intensity with respect to all–cause mortality among US adults diagnosed with metabolic dysfunction–associated steatotic liver disease (MASLD). …”
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    Coronary plaque characteristics quantified by artificial intelligence-enabled plaque analysis: Insights from a multi-ethnic asymptomatic US population by Guadalupe Flores Tomasino, Caroline Park, Kajetan Grodecki, Jolien Geers, Donghee Han, Andrew Lin, Keiichiro Kuronuma, Nipun Manral, Emily Xing, Heidi Gransar, Sebastien Cadet, Alan Rozanski, Piotr J. Slomka, Michelle Williams, Daniel S. Berman, Damini Dey

    Published 2025-03-01
    “…We aimed to assess quantitative plaque characteristics from coronary CT Angiography (CCTA) in relation to ethnicity and cardiovascular risk factors in a multi-ethnic asymptomatic US population. Methods: This cross-sectional study retrospectively evaluated 388 asymptomatic patients selected from a prospective CCTA registry. …”
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