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In Vitro and In Silico Cytotoxic and Antibacterial Activities of a Diterpene from Cousinia alata Schrenk
Published 2021-01-01“…The presence of the essential pharmacophoric features of histone deacetylase (HDAC) inhibitors in the structure of grindelic acid encouraged us to run a molecular docking study against the HDAC enzyme to understand its mechanism of action on a molecular level. …”
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Certain Death: Mike Flanagan’s Gothic Antidote to Traumatic Memory and Other Enlightenment Hang-Overs in <i>Doctor Sleep</i>
Published 2025-01-01“…In this way, I illustrate and encourage future study of how Gothic texts not only point to marginalized, repressed problems, but more importantly, how they help us relate differently to a traumatic past and innovate strategies for immediate relief from inherited suffering.…”
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A Change in the Classical Order of Setting of Porous Metal Augments with Locked Cups in Hip Revision Surgery: Technical Note and Case Report
Published 2022-01-01“…The interlocking mechanism offers an additional biomechanical stability and thus may allow us to place the cup first in the desired position with a less demanding technique. …”
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Investigating the research landscape of chlorinated paraffins over the past ten decades
Published 2025-01-01“…This scientometric analysis allowed us to infer global trends in CPs, identify tendencies and gaps, and contribute to future research. …”
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TRANSFORMATION REFLEXES OF PRE-CHRISTIAN WORLDVIEW IN KIEVAN RUS LITERATURE
Published 2015-05-01“…Among the general scientific approaches in solving the problems that have been used was primarily theological and philosophical. This approach allowed us to explore and objectively analyze the tendency to reflect pre-Christian beliefs in the literature of Kievan Rus. …”
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Adult Intra-Thoracic Kidney: A Case Report of Bochdalek Hernia
Published 2010-01-01“…Abdominal X-ray and chest X-ray revealed dilated loops of the colon above left hemidiaphragm. Abdominal ultrasound (US) showed the right kidney with many fluid and esophytic cysts; left kidney was unfeasible to study because of the impossibility to find it. …”
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Older People's Perceptions of Well-Being
Published 2025-01-01“…The obtained results allow us to say that well-being in the ideas of elderly people is health combined with emotions of calmness and happiness. …”
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Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology
Published 2025-01-01“…Apremilast was the first PDE4 inhibitor approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for psoriasis, psoriatic arthritis, and oral ulcers of Behcet’s disease. …”
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Criteria base of the Hartmann–Sprenger pipe workflow
Published 2024-06-01“…Finding dimensionless complexes based on the modeling theory allowed us to determine the criteria base of the Hartmann–Sprenger pipe workflow.…”
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Coprescribing of opioids and high-risk medications in the USA: a cross-sectional study with data from national ambulatory and emergency department settings
Published 2022-06-01“…Objective Describe trends in opioid plus high-risk medication coprescribing in the USA.Design Analyses of serial, cross-sectional, nationally representative data of the National Ambulatory Medical Care Survey (NAMCS) over 2007–2016 and the National Hospital Ambulatory Medical Care Survey (NHAMCS) over 2007–2018.Setting US ambulatory (NAMCS) and emergency department (ED, NHAMCS) settings.Participants Patient visits in which the patient was 18 years and older with an opioid prescription in the NAMCS or NHAMCS databases.Primary and secondary outcome measures Frequency of opioid plus high-risk medication coprescribing.Results From a combined sample of 700 499 visits over 2007–2018, there were 105 720 visits (15.1%) where opioids were prescribed. n=31 825 were from NAMCS and n=73 895 were from NHAMCS. …”
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A reliable supply chain network design for perishable crops with disruption risk consideration (case study: tomato supply chain)
Published 2024-12-01“…Moreover, considering the disruptions and protection of products brings us closer to real-world conditions and reduces the amount of waste and related adverse environmental effects.Originality/Value: Agriculture is one of the most important and influential sectors in the economy of any country, it plays a vital role in its political and economic independence. …”
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