Exploring the potential cost-effectiveness and societal burden implications of screening for fracture risk in a UK general radiography setting by E. Söreskog, B. Lopez, T. Bean, P. Lewis, N. Ashley, J. Da Palma Lopes, R. Meertens, A. Ratcliffe

“…Conclusions IBEX BH could be a cost-effective tool for early identification and prevention of fragility fractures in the UK, addressing the current challenges of low provision and access to fracture risk assessment and treatment.…”
Get full text

TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…Treatment options and robust trial data are limited.Objectives The TOURISM study (Treatment Outcomes in UteRIne SarcoMa) is a UK-wide study by the National Oncology Trainees Collaborative for Healthcare Research which aimed to characterise this patient cohort.Design A retrospective descriptive cohort study. …”
Get full text

Cohort study evaluating pressure ulcer management in clinical practice in the UK following initial presentation in the community: costs and outcomes by Julian F Guest, Graham W Fuller, Peter Vowden, Kathryn Ruth Vowden

“…Objectives The aim of this study was to estimate the patterns of care and annual levels of healthcare resource use attributable to managing pressure ulcers (PUs) in clinical practice in the community by the UK’s National Health Service (NHS), and the associated costs of patient management.Methods This was a retrospective cohort analysis of the records of 209 patients identified within a randomly selected population of 6000 patients with any type of wound obtained from The Health Improvement Network (THIN) Database, who developed a PU in the community and excluded hospital-acquired PUs. …”
Get full text

Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

Subjects: Get full text

Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts by Muataz S. Lafta, Aleksandr V. Sokolov, Gull Rukh, Helgi B. Schiöth

Subjects: “…UK biobank…”
Get full text

Health and associated economic benefits of reduced air pollution and increased physical activity from climate change policies in the UK by Heather Walton, David Dajnak, Mike Holland, Dimitris Evangelopoulos, Dylan Wood, Christian Brand, Nosha Assareh, Gregor Stewart, Andrew Beddows, Shawn YC Lee, Daniela Fecht, Yunzhe Liu, Bethan Davies, Anna Goodman, Tuan Vu, Sean Beevers

“…We compared business as usual (BAU) UK policy with Net Zero scenarios from the UK Climate Change Committee for road transport and building sectors. …”
Get full text

Postpartum depression in relation to chronic diseases and multimorbidity in women’s mid-late life: a prospective cohort study of UK Biobank by Yue Zhang, Yangyang Cheng, Rodrigo M. Carrillo-Larco, Yaguan Zhou, Hui Wang, Xiaolin Xu

“…Methods This prospective cohort study included female participants in UK Biobank who attended online follow-up assessment and reported their history of PPD. …”
Get full text

Understanding good communication in ambulance pre-alerts to the emergency department: findings from a qualitative study of UK emergency services by Rachel O’Hara, Joanne Coster, Fiona C Sampson, Jaqui Long

“…We undertook qualitative research to understand how pre-alert communication may be improved to optimise the ED response for pre-alerted patients.Design, setting and participants Data collection took place within three UK Ambulance Services and six EDs between August 2022 and April 2023. …”
Get full text

Comparing the emotional impact of the UK COVID-19 lockdown in very preterm and full-term born children: a longitudinal study by Zeyuan Sun, Zeyuan Sun, Laila Hadaya, Laila Hadaya, Marguerite Leoni, Marguerite Leoni, Paola Dazzan, Emily Simonoff, Serena J. Counsell, A. David Edwards, Chiara Nosarti, Chiara Nosarti, Lucy Vanes

Get full text

Assessment of the Performance of ²¹⁰Pb-Based Dating Models with a Challenging Sediment History in Maryport Harbour (UK) by José M. Abril-Hernández

“…The performance of the classical models, CFCS and CRS, and the novel TERESA is assessed with a 2 m long, high-resolution core sampled in Maryport Harbour, UK, by using raw data from the literature. It was affected by dredging, shortening, and by the anthropogenic impacts of radionuclides released by the Sellafield nuclear plant and the phosphate industry in Whitehaven and was considered non-datable by the ²¹⁰Pb method. …”
Get full text

Modelling Socio-Environmental Sensitivities: How Public Responses to Low Carbon Energy Technologies Could Shape the UK Energy System by Brighid Moran Jay, David Howard, Nick Hughes, Jeanette Whitaker, Gabrial Anandarajah

Get full text

British Edition of the Monroe Doctrine versus ‘Com- munist Militarism’: Collisions between the USSR and the UK in Eastern Countries in the mid-1920s by E. Yu. Sergeev

“…The prospect of unfettered Bolshevik expansion into British colonies and dependent territories in Asia and Africa became a matter of particular concern for the UK ruling circles. It was this threat that forced the military and political elites of Great Britain to turn to the experience of their overseas counterparts and develop a set of measures that can be described as the British edition of the Monroe Doctrine. …”
Get full text

Exploring community stakeholder perspectives of partnership development in community-engaged undergraduate Global Health Education in the UK: a qualitative study by Shyam Sundar Budhathoki, Helen Ward, Dorota Chapko, Christine Pettitt, Keitumetse-Kabelo Murray

“…This study explores the perspectives of members of community-based organisations (CBOs) who were partnered with a community engagement programme for intercalating medical students at Imperial College London.Design A qualitative study using semistructured interviews was conducted, employing reflexive thematic analysis.Setting London, UK.Participants A total of five participants (one member from five CBOs who agreed to participate) were interviewed for this study. …”
Get full text

Delphi study to identify consensus on patient selection for hydrogel rectal spacer use during radiation therapy for prostate cancer in the UK by Amit Bahl, Suneil Jain, Albert Edwards, Rhodri Saunders, Clive Peedell, Heather Ann Payne, James Andrew Thomas, Prantik Das, Amanda Hansson Hedblom, Emily Woodward

“…Objectives To identify consensus on patient prioritisation for rectal hydrogel spacer use during radiation therapy for the treatment of prostate cancer in the UK.Design Delphi study consisting of two rounds of online questionnaires, two virtual advisory board meetings and a final online questionnaire.Setting Radical radiation therapy for localised and locally advanced prostate cancer in the UK.Participants Six leading clinical oncologists and one urologist from across the UK.Interventions Rectal hydrogel spacer.Primary and secondary outcome measures None reported.Results The panel reached consensus on the importance of minimising toxicity for treatments with curative intent and that even low-grade toxicity-related adverse events can significantly impact quality of life. …”
Get full text

Cardiovascular risk profiles and the uptake of the NHS Healthcheck programme in male prisoners in six UK prisons: an observational cross-sectional survey by Kamlesh Khunti, Richard Morriss, Christopher Packham, Elizabeth Butcher, Marie Williams, Joanne Miksza

Get full text

Artificial intelligence assisted risk prediction in organ transplantation: a UK Live-Donor Kidney Transplant Outcome Prediction tool by Hatem Ali, Arun Shroff, Tibor Fülöp, Miklos Z. Molnar, Adnan Sharif, Bernard Burke, Sunil Shroff, David Briggs, Nithya Krishnan

“…The calibration process was adequate, as evidenced by the IBS score of 0.09.Conclusion: By evaluating possible donor–recipient pairs based on graft survival, the AI-based UK Live-Donor Kidney Transplant Outcome Prediction has the potential to enhance choices for the best live-donor selection. …”
Get full text

Barriers to accessing mental health services for women with perinatal mental illness: systematic review and meta-synthesis of qualitative studies in the UK by Megan Sambrook Smith, Vanessa Lawrence, Euan Sadler, Abigail Easter

“…Objective Lack of access to mental health services during the perinatal period is a significant public health concern in the UK. Barriers to accessing services may occur at multiple points in the care pathway. …”
Get full text

Translation of the UK Pediatric Influenza Vaccination Programme in Primary Schools to 13 European Countries Using a Dynamic Transmission Model by Laetitia Gerlier, Judith Hackett, Richard Lawson, Sofia Dos Santos Mendes, Martin Eichner

“…In adults, the range of ORs for PCC was 0.60–0.91 (UK OR=0.41 [0.19; 0.86]). NNV ranges were 6–19 per averted PCC (UK NNV=16), 530–1524 per averted hospitalization (UK NNV=317) and 5298–15 241 per averted ICU admission (UK NNV=2205). …”
Get full text

Evaluating the Effectiveness of Primary Care Health Checks at Assessing Cardiovascular Risks among Ethnic Minorities in the UK: A Systematic Review by Aleesha Karia, Reza Zamani, Tanimola Martins, Abdal Zafar, Ava Zamani

“…Background: Cardiovascular diseases (CVD) affect around 7.6 million people in the UK, disproportionately affecting the minority ethnic community. …”
Get full text

Service delivery and the role of clinical pharmacists in UK primary care for older people, including people with dementia: a scoping review by Alice Burnand, Abi Woodward, Vladimir Kolodin, Jill Manthorpe, Yogini Jani, Mine Orlu, Cini Bhanu, Kritika Samsi, Victoria Vickerstaff, Jane Wilcock, Jane Ward, Greta Rait, Nathan Davies

“…This review explores how clinical pharmacists working in UK primary care support older people and people with dementia. …”
Get full text