Helping people with psychosis with a low-cost intervention DIALOG+: protocol for the economic evaluation in a randomised control trial in India and Pakistan by Victoria Jane Bird, Sara Evans-Lacko, Lakshmi Venkatraman, Padmavati Ramachandran, Ashar Muhammad Malik, Renata Peppl, Sana Zehra Zehra Sajun, Onaiza Qureshi, Krishna Priya, Hufsa Sarwar

“…The economic evaluation will support efforts to scale up low-cost healthcare interventions such as DIALOG+ to rural and unserved areas, which is otherwise challenging in the resource-constrained health systems in many LMICs.Conclusion The evidence on the cost-effectiveness of DIALOG+ will contribute to efforts to improve community-based care and the quality of life for millions of people suffering from mental health problems in India and Pakistan who experience psychosis.Ethics and dissemination This study is approved by the Queen Mary Ethics of Research Committee (UK), Institutional Ethics Committee of SCARF (India), IRD’s Independent Institutional Review Board (IRD_IRB_2021_01_005) (Pakistan), Karawan-e-Hayat Management Committee (Institutional Approval) (Pakistan), Jinnah Postgraduate Medical Centre Research Committee (NO.F.2-81/2021-GENL/60224/JPMC) (Pakistan), Aga Khan’s Ethics Research Committee (2021-5933-17533) (Pakistan) and National Bio-Ethics Committee, Pakistan (Ref: No.4–87/NBC-774/22/2037 Date: 17 May 2022).The findings of this research will be widely disseminated through research publications and engagement with the communities and the healthcare providers in the public and not-for-profit sectors.Trial registration number ISRCTN13022816.…”
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Patient preferences for drug therapy in inflammatory arthritis: protocol for a living systematic review and evidence map to inform clinical practice guidelines by Rachelle Buchbinder, Peter Tugwell, Pablo Alonso-Coello, Mickael Hiligsmann, Nick Bansback, Laurie Proulx, Dawn P Richards, Wojtek Wiercioch, Glen Hazlewood, Samuel Whittle, Jordi Pardo Pardo, Marie Falahee, Holger Schünemann, Robby Nieuwlaat, Pakeezah Saadat, Simon Kuper

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Use of rituximab in mature, high-grade and advanced-stage pediatric B-lineage non-Hodgkin lymphomas: a systematic review, meta-analysis and the Brazilian reality by Alejandra Adriana Cardoso de Castro, Alejandra Adriana Cardoso de Castro, Alejandra Adriana Cardoso de Castro, Liana Alves de Oliveira, Liana Alves de Oliveira, Diancarlos Pereira de Andrade, Edna Kakitani Carbone, Edna Kakitani Carbone, Roberto Rosati, Roberto Rosati, Roberto Rosati

“…However, access to rituximab in Brazilian hospitals is currently dependent on centers supporting its economic burden.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, PROSPERO (CRD42021292912).…”
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Epilepsy and brain health: a large prospective cohort study by Dan-Dan Zhang, Zi-Yi Wang, Ya-Ru Zhang, Pei-Yang Gao, Wei Zhang, Yan Fu, Hao-Chen Chi, Li-Yun Ma, Yi-Jun Ge, Xiao-Yu He, Jia You, Wei Cheng, Jian-Feng Feng, Lan Tan, Jin-Tai Yu

“…Methods The study was based on clinical diagnostic and test data from 426,527 participants in the UK Biobank, of whom 3,251 were diagnosed with epilepsy at baseline. …”
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Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease by Geetika Nehra, Bryan J. Maloney, Rebecca R. Smith, Wijitra Chumboatong, Erin L. Abner, Peter T. Nelson, Björn Bauer, Anika M. S. Hartz

“…Methods We used postmortem brain tissue and plasma samples from 19 participants: 9 CNI and 10 AD dementia patients who had come to autopsy from the University of Kentucky AD Research Center (UK-ADRC) community-based cohort; all cases with dementia had confirmed severe ADNC. …”
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Exploring the barriers to cervical screening and perspectives on new self-sampling methods amongst under-served groups by Stephanie Gillibrand, Helen Gibson, Kelly Howells, Sean Urwin, Jennifer C. Davies, Emma J. Crosbie, Caroline Sanders

“…Abstract Background Cervical screening rates have fallen in recent years in the UK, representing a health inequity for some under-served groups. …”
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Patterns and factors associated with healthcare utilisation in Cambodia: a cross-sectional study based on the World Health Survey Plus 2023 by Kerstin Klipstein-Grobusch, Por Ir, Paul Kowal, Nawi Ng, Srean Chhim, Chhorvann Chhea, Chamnab Ngor, Sereyraksmey Long, Poppy Walton, Khin Thiri Maung, Grace Marie Ku, Heng Sopheab

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Interventions for Digital Addiction: Umbrella Review of Meta-Analyses by Peng Lu, Jiamin Qiu, Shiqi Huang, Xinman Wang, Shasha Han, Sui Zhu, Youjing Ning, Fang-fang Zeng, Yuan Yuan

“…Trial RegistrationPROSPERO CRD42024528173; crd.york.ac.uk/PROSPERO/display_record.php?RecordID=528173…”
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Utilization of biomass ash generated from combined heat and power generation system as a multi-nutrient source for crops by Tirthankar Mohanty, Subhaprada Dash, Priyabrata Pattanaik, Hara Prasada Tripathy, J.M.L. Gulati, Dilip Kumar Mishra, William Holderbaum

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Association between the intensity of statin therapy and physical activity 1 year after acute coronary syndrome: a multicentre prospective cohort study in Switzerland by David Nanchen, Stephan Windecker, Isabella Locatelli, Nicolas Rodondi, Lorenz Räber, David Carballo, Francois Mach, Olivier Muller, Baris Gencer, Christian M Matter, Roland Klingenberg, Thomas Lüscher, Alex Boudon

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Alterations of interhemispheric functional connectivity in patients with hypertensive retinopathy using voxel-mirrored homotopic connectivity: a resting state fMRI study by Xue-Lin Wang, Yu Chen, Jin-Yu Hu, Hong Wei, Qian Ling, Liang-Qi He, Cheng Chen, Yi-Xin Wang, Yan-Mei Zeng, Xiao-Yu Wang, Qian-Min Ge, Xu Chen, Yi Shao

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Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…The NSWD is a large‐scale cross‐sectional, representative sample of adults across Wales, UK. A univariable and multivariable regression analysis was carried out on self‐reported answers to health and well‐being questions contained within the NSWD (2016–2020) to determine the strength of association of various determinants and comorbidities related to spinal pain. …”
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Effects of virtual reality technology on early mobility in critically ill adult patients: a systematic review and meta-analysis by Yansha He, Yansha He, Qin Yang, Xiaoxia Dai, Tian Chen, Huan Wu, Kunjie Li, Shiqiong Zhu, Yanlin Liu, Hua Lei

“…However, the effect of enhancing the functional independence of limbs is not yet evident and still needs to be confirmed by high-quality, multicenter, and large-sample clinical trials.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/ Prospero register No.: CRD42024546409.…”
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Quality of life among residents of informal urban settlements during the COVID-19 pandemic in Salvador, Brazil by Albert I Ko, Federico Costa, Hammed Mogaji, Nivison Nery, Hernan D Argibay, Jaqueline S Cruz, Ianei O Carneiro, Ricardo Lustosa, Mike Begon, Hussein Khalil

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Assessment of relative energy deficiency in sport and malnutrition prevalence in female endurance runners by energy availability questionnaire, bioelectrical impedance analysis and... by Samantha Sharp, Roni Mashiach-Fransis, Nicola Keay, Adrian Slee

“…Methods: 70 female runners from London, UK running clubs participated in this study. The median age of the participants was 32 years old (range 18–55 years old), with mean ± SD BMI 21.2±2.4 kg/m2. …”
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Mendelian randomization studies of risk and protective factors for osteoporosis: a systematic review and meta-analysis by Wenhao Ji, Wenhao Ji, Bin Pan, Bin Pan, Xin Chen, Xin Chen, Zhaobai Lao, Zhaobai Lao, Wanlei Yang, Wanlei Yang, Yu Qian, Yu Qian

“…However, the association between obesity, type 2 diabetes mellitus, metformin, ulcerative colitis, leisure sedentary behaviors, systemic lupus erythematosus, serum iron and osteoporosis was found to be nonsignificant.ConclusionIn summary, our meta-analysis indicates that significant causal relationships with osteoporosis’s onset and progression have been established for rheumatoid arthritis, inflammatory bowel disease, primary biliary cholangitis, non-alcoholic fatty liver disease, depression, sex hormone binding globulin, basal metabolic rate, gut microbiota (NB1n), and asthma.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier PROSPERO CRD42024540504.…”
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Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egy... by Giuseppe Indolfi, Diana M Gibb, Aya Mostafa, Sarah Pett, Yazdan Yazdanpanah, Sylvie Deuffic-Burban, Anthony E Ades, Karen Scott, Ali Judd, Nadia Hachicha-Maalej, Clotilde Lepers, Intira Jeannie Collins, Manal H El Sayed

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Mixed methods evaluation of the Getting it Right First Time programme in elective orthopaedic surgery in England: an analysis from the National Joint Registry and Hospital Episode... by Stephen Morris, James Mason, Rosalind Raine, Peter Martin, Naomi J Fulop, Elena Pizzo, Andrew Hutchings, Helen Barratt, Jean Ledger, Raj Mehta, Sarah Jasim, Fiona Aspinal, Rafael Gafoor

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Development of an individualized dementia risk prediction model using deep learning survival analysis incorporating genetic and environmental factors by Shiqi Yuan, Qing Liu, Xiaxuan Huang, Shanyuan Tan, Zihong Bai, Juan Yu, Fazhen Lei, Huan Le, Qingqing Ye, Xiaoxue Peng, Juying Yang, Yitong Ling, Jun Lyu

“…Methods and results This study is based on a large prospective cohort from the UK Biobank, which includes a total of 41,484 participants with an average follow-up period of 12.6 years. …”
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Green sanctuaries: residential green and garden space and the natural environment mitigate mental disorders risk of diabetic patients by Erxu Xue, Jianhui Zhao, Jingyu Ye, Jingjie Wu, Dandan Chen, Jing Shao, Xue Li, Zhihong Ye

“…Methods We performed a longitudinal analysis based on 39,397 participants with diabetes from the UK Biobank. Residential green and garden space modeled from land use data and the natural environment from Land Cover Map were assigned to the residential address for each participant. …”
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