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Evolution and effectiveness of bilateral and multilateral development assistance for health: a mixed-methods review of trends and strategic shifts (1990–2022)
Published 2025-01-01“…Major contributors to DAH included the USA, the UK and the Bill & Melinda Gates Foundation. …”
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Protective role of ginsenoside Rg1 in the dynamic progression of liver injury to fibrosis: a preclinical meta-analysis
Published 2025-01-01“…Time-dose interval analysis revealed that the effective dose range of ginsenoside Rg1 was between 4 and 800 mg/kg/d.ConclusionRg1 at a dose of 4–800 mg/kg/d mitigates the progression of liver injury to fibrosis via anti-inflammatory, antioxidative, and anti-apoptotic pathways.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD 42024557878.…”
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Recent Developments to the ANSWERS® Monte Carlo Codes MONK® and MCBEND®
Published 2024-01-01“…MONK® and MCBEND® are two advanced Monte Carlo codes developed by the ANSWERS® Software Service, which have been used in over 30 countries worldwide for a range of applications, and have been well-established in the UK criticality and shielding communities respectively over the course of several decades. …”
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Taking a partnership approach to embed physical activity in local policy and practice: a Bradford District case study
Published 2025-01-01“…The aim of this study was to examine ‘what works’, and identify factors underpinning change, focused on work to embed physical activity in local policy and practice in Bradford, UK. Methods A mixed-methods case study approach involved collecting data from cross-sectoral stakeholders directly or indirectly engaged in the physical activity agenda in Bradford over a period of three years (2021–2024). …”
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The prognostic utility of the ratio of lymphocyte to monocyte in patients with metastatic colorectal cancer: a systematic review and meta-analysis
Published 2025-02-01“…However, further high-quality prospective studies are warranted to validate our findings since the majority of current investigations have relied on retrospective study designs.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024496467, identifier CRD42024496467.…”
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Using OCO-2 Observations to Constrain Regional CO<sub>2</sub> Fluxes Estimated with the Vegetation, Photosynthesis and Respiration Model
Published 2025-01-01“…We investigated the potential of our inversion system by applying it to a European region (that includes, in particular, the EU countries and the UK) for the warm season (May–September) of 2021. …”
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Protocol for an adaptive platform trial of intended service user-derived interventions to equitably reduce non-attendance in eye screening programmes in Botswana, India, Kenya and...
Published 2025-02-01“…Approvals for individual interventions will be sought from UK and local ethics committees. Results will be shared via local workshops, social media and peer-reviewed publications.Trial registration number ISRCTN53970958.…”
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Understanding stakeholder views of the use of digital therapeutic interventions within children and young people’s mental health services
Published 2025-02-01“…Increased use of digital technology in the delivery of children and young people’s mental health services has been proposed as a means of increasing access to treatment.MethodsWe conducted three interrelated studies to provide multi-perspective insights into the use of digital therapeutic interventions within children and young people’s mental health services in the UK. Study 1 used semi-structured interviews and an online survey to collect the views of digital therapeutic interventions of families who self-identified as facing additional barriers to accessing mental health support (n=13). …”
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Exome-wide genetic risk score (ExGRS) to predict high myopia across multi-ancestry populations
Published 2024-12-01“…This study enrolled two independent cohorts: 12,600 unrelated individuals of Han Chinese ancestry from Myopia Associated Genetics and Intervention Consortium (MAGIC) and 8682 individuals of European ancestry from UK Biobank (UKB). Results Here, we first estimate the heritability of HM resulting in 0.53 (standard error, 0.06) in the MAGIC cohort and 0.21 (standard error, 0.10) in the UKB cohort by using whole-exome sequencing (WES) data. …”
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Systemic Inflammatory Markers for Predicting Overall Survival in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis
Published 2021-01-01“…PROSPERO (CRD42021249954), https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=249954.…”
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Through each other's eyes: initial results and protocol for the co-design of an observational measure of adolescent-parent interaction using first-person perspective
Published 2024-03-01“…We also undertook public engagement work utilising a mobile research van, taken to multiple locations around Bristol, UK to engage with a variety of populations through interactive methods. …”
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