Showing 2,941 - 2,960 results of 3,363 for search '"UK"', query time: 0.08s Refine Results
  1. 2941
  2. 2942

    Polygenic prediction of human longevity on the supposition of pervasive pleiotropy by M. Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang, Zhen Wang, Joydeep Mitra, Nha Nguyen, Tina Gao, Mark Khusidman, Sanish Sathyan, Gil Atzmon, Sofiya Milman, Jan Vijg, Nir Barzilai, Zhengdong D. Zhang

    Published 2024-08-01
    “…We tracked allele frequency changes as a function of viability across different age bins and prioritized 34 variants with an immediate implication on lipid metabolism, body mass index (BMI), and cognitive performance, among other traits, revealed by PheWAS analysis in the UK Biobank. Given the highly complex and non-linear interactions between the genetic determinants of longevity, we reasoned that a composite polygenic score would approximate a substantial portion of the variance in lifespan and developed the integrated longevity genetic scores (iLGSs) for distinguishing exceptional survival. …”
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  3. 2943

    Efficacy and safety of nivolumab plus ipilimumab in gastrointestinal cancers: a systematic review and meta-analysis by Bowen Dai, Jiaping Jiang, Xiaoyu Yu, Haihua Zhan, Zhengchuan Hu

    Published 2025-01-01
    “…However, its efficacy in biliary cancer still needs to be further proven.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024590994.…”
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  4. 2944

    Draft genome sequence of a co-harbouring blaNDM-5 and mcr-1.1 Escherichia coli phylogroup A isolate associated with patient colonisation in Ireland by Anna Tumeo, Francesca McDonagh, Aneta Kovarova, Kate Ryan, Christina Clarke, Georgios Miliotis

    Published 2025-01-01
    “…Plasmid replicons associated with the spread of MDR genes such as IncHI2/HI2A were detected. wgMLST analysis showed the closest relative being a strain from the UK, exhibiting differences in the sequences of 851 genes. …”
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  5. 2945

    Novel application of an imageless robotic system in simultaneous unicompartmental knee arthroplasty and anterior cruciate ligament reconstruction by Joshua Yeuk Shun Tran, Rex Wang-Fung Mak, Kevin Ki-Wai Ho, Jonathan Patrick Ng, Cham Kit Wong, Gloria Yan-Ting Lam, Tsz Lung Choi, Michael Tim-Yun Ong, Patrick Shu-Hang Yung

    Published 2025-01-01
    “…The patient underwent a simultaneous robotic-assisted UKA and ACLR using the CORI Surgical System (Smith&Nephew, London, UK). This approach enables accurate tibial tunnel placement and precise soft tissue balancing. …”
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  6. 2946

    Effect of Multimodal App-Based Interventions on Glycemic Control in Patients With Type 2 Diabetes: Systematic Review and Meta-Analysis by Emma Bodner, Lena Roth, Kathleen Wiencke, Christian Bischoff, Peter EH Schwarz

    Published 2025-01-01
    “…Trial RegistrationPROSPERO CRD42023440203; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=440203…”
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  7. 2947
  8. 2948

    Effects of exercise training on the nigrostriatal glutamatergic pathway and receptor interactions in Parkinson’s disease: a systematic review by Shahid Ishaq, Iqbal Ali Shah, Shin-Da Lee, Shin-Da Lee, Bor-Tsang Wu

    Published 2025-02-01
    “…It also improved motor function, including balance, coordination, and gait parameters.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/#recordDetails, identifier CRD42024564127…”
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  9. 2949

    Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level by Giusy Rita Maria La Rosa, Alejandro Ismael Lorenzo-Pouso, Vito Carlo Alberto Caponio, Mariangela Valentina Puci, Mariangela Valentina Puci

    Published 2025-02-01
    “…Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=411038, PROSPERO (CRD42023411038).…”
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  10. 2950

    Genetic Associations Between Specific Sleep-Related Phenotypes and Idiopathic Sudden Sensorineural Hearing Loss: A Mendelian Randomization Analysis by Li M, He J, Liang Y, Zou F, Gou C, Lv J, Zhang X, Li D, Yu Z

    Published 2025-02-01
    “…This study was designed to investigate the link between SRPs and ISSNHL from a genetic perspective through Mendelian randomization (MR) analysis.Methods: ISSNHL trials were downloaded from Finngen database. SRPs were from the UK Biobank and FinnGen database. The inverse variance weighted (IVW) method was utilized, followed by confirming the robustness and reliability using the MR Egger, weighted median, simple mode, and weighted mode. …”
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  11. 2951

    Effect of invasive acupuncture on awakening quality after general anesthesia: systematic review and meta-analysis by Fan-dong Bu, Shang-kun Si, Shang-kun Si, Shang-kun Si, Dong-bin Zhang, Yong-liang Chi

    Published 2025-01-01
    “…No statistical difference in the occurrence of POCD (OR = 0.56, 95% CI [0.28, 1.11], p = 0.10) and postoperative agitation (OR = 0.42, 95% CI [0.11, 1.65], p = 0.21).Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, CRD42023410260.…”
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  12. 2952
  13. 2953

    Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalab... by Najma Siddiqi, Chao Huang, Maureen Twiddy, Miriam Johnson, Margaret Ogden, Kathryn Sartain, Imogen Featherstone, Jason Boland, Mark Pearson, Catriona Jackson, Gillian Jackson

    Published 2022-07-01
    “…The primary objective of this study is to demonstrate the feasibility of an implementation strategy (designed to help deliver good practice delirium guidelines), participant recruitment and data collection.Methods and analysis Three work packages in three hospices in the UK with public involvement in codesign, study management and stakeholder groups: (1) experience-based codesign to adapt an existing theoretically-informed implementation strategy (Creating Learning Environments for Compassionate Care (CLECC)) to implement delirium guidelines in hospices; (2) feasibility study to explore ability to collect demographic, diagnostic and delirium management data from clinical records (n=300), explanatory process data (number of staff engaged in CLECC activities and reasons for non-engagement) and cost data (staff and volunteer hours and pay-grades engaged in implementation activities) and (3) realist process evaluation to assess the acceptability and flexibility of the implementation strategy (preimplementation and postimplementation surveys with hospice staff and management, n=30 at each time point; interviews with hospice staff and management, n=15). …”
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  14. 2954
  15. 2955

    Participant Compliance With Ecological Momentary Assessment in Movement Behavior Research Among Adolescents and Emerging Adults: Systematic Review by Shirlene Wang, Chih-Hsiang Yang, Denver Brown, Alan Cheng, Matthew Y W Kwan

    Published 2025-02-01
    “…Trial RegistrationPROSPERO CRD42021282093; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=282093…”
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  16. 2956

    Towards a common approach for managing food allergy and serious allergic reactions (anaphylaxis) at school. GA2LEN and EFA consensus statement by Antoine Deschildre, Montserrat Alvaro‐Lozano, Antonella Muraro, Marcia Podesta, Debra deSilva, Mattia Giovannini, Simona Barni, Timothy E. Dribin, Mónica Sandoval‐Ruballos, Aikaterini Anagnostou, Alessandro Fiocchi, Alice Toniolo, Andrew Bird, Angel Sánchez Sanz, Anna Asarnoj, Anna Nowak‐Wegrzyn, Berber Vlieg‐Boerstra, Brian P. Vickery, Carina Venter, Caroline Nilsson, Cecilia Parente, Céline Demoulin, David M. Fleischer, Diola Bijlhout, Edward F. Knol, Eleanor Garrow, Emma E. Cook, Fallon Schultz, Francesca Lazzarotto, Francesca Mori, Gary Wong, Gideon Lack, Graham Roberts, Gustavo Andres Marino, H. N. G. Oude Elberink, Helen A. Brough, Hugh A. Sampson, Jay Lieberman, Jennifer Gerdts, Jing Zhao, Josefine Gradman, Julia E. M. Upton, Julie Wang, Kati Palosuo, Kirsi M. Järvinen, Kirsten Beyer, Kunling Shen, Laura Polloni, Lianne Mandelbaum, Luciana Kase Tanno, Lucy A. Bilaver, Marcus S. Shaker, Margitta Worm, Maria Said, Mary Kelly, Mary Jane Marchisotto, Michael Makris, Mikaela Odemyr, Montserrat Fernandez‐Rivas, Motohiro Ebisawa, Nandinee Patel, Pablo Rodríguez del Río, Pakit Vichyanond, Paul Turner, Pete Smith, Pilar Morón Gaspar, R. Sharon Chinthrajah, Rima Rachid, Roberta Bonaguro, Ruchi Gupta, Sabine Schnadt, Sakura Sato, Stefania Arasi, Stephanie Leonard, Sung Poblete, Susanne Halken, Thuy‐My Le, Guillaume Pouessel, Tracey Dunn, Victoria Cardona, Torsten Zuberbier

    Published 2025-01-01
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  17. 2957
  18. 2958
  19. 2959

    CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

    Published 2025-01-01
    “…Zahid Hussain,1,2 Lama Abdulrahim Abdul Moti,1 Jayalakshmi Jagal,2 Hnin Ei Thu,3 Shahzeb Khan,4 Mohsin Kazi5 1Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; 2Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; 3Department of Pharmacology, Faculty of Dentistry, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia; 4Center for Pharmaceutical Engineering Science, Faculty of Life Sciences, School of Pharmacy and Medical Sciences, University of Bradford, West Yorkshire Bradford, BD7 1DP, UK; 5Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451 Saudi ArabiaCorrespondence: Zahid Hussain, Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates, Email zhussain@sharjah.ac.aeIntroduction: Owing to its high prevalence, colossal potential of chemoresistance, metastasis, and relapse, breast cancer (BC) is the second leading cause of cancer-related fatalities in women. …”
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  20. 2960