Efficacy and safety of intravenous ferric carboxymaltose in the treatment of Restless Legs Syndrome: a systematic review and meta-analysis by Ayesha Khan, Harsh Kumar, Kuldeep Dalpat Rai, Anzel Saeed, Jawad Ishtiaq, Muhammad Tanveer Alam, Sakshi Chawla, Md Ariful Haque, Md Ariful Haque

“…However, further long-term studies are needed to fully assess the safety profile and confirm sustained symptom improvement in a broader population.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42024585233.…”
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Understanding the implementation strategy of a secondary care tobacco addiction treatment pathway (the CURE project) in England: a strategic behavioural analysis by Matthew Evison, Anna Haste, Catherine Haighton, Freya Howle, Angela M Rodrigues, Angela Wearn, Verity Mallion

“…This study aimed to (1) specify key characteristics of CURE’s exiting implementation strategy and (2) develop theoretical-informed and stakeholder-informed recommendations to optimise wider roll-out.Design and methods Data were collected via document review and secondary analysis of interviews with 10 healthcare professionals of a UK hospital. Intervention content was specified through behaviour change techniques (BCTs) and intervention functions within the Behaviour Change Wheel. …”
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Cost minimization analysis of nasopharyngoscope reprocessing in community practice by Ameen Biadsee, Lauren Crosby, Winsion Chow, Leigh J Sowerby

“…., Mississauga, Canada), (3) disinfection with chlorine dioxide wipe (Tristel Trio Wipes System; Tristel plc., Cambridgeshire, UK), (4) UV-C light system (UV Smart, Delft, The Netherlands). …”
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Clinical Predictors of Aspirin Resistance in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis by Fan Zhang, Hongyan Zheng

“…The PROSPERO registration: CRD42023388170, https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=388170…”
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The double-edged sword of statins in intracerebral hemorrhage patients: a systematic review and meta-analysis by Zheng Li, Wen-qi Xu, Jiao-qi Wang, Jia-hui Yang, Xiao-hua Shi, Cheng-bing Wang, Zhong-xin Xu, Jin-lan Jiang

“…Subgroup analyses further demonstrated lower mortality in ICH patients treated with statins compared to those not treated, including in the propensity score matching (PSM) group (OR: 0.59; 95% CI: 0.48–0.74; I2 = 90%; p < 0.01), the prospective cohort study (PCS) group (OR: 0.56; 95% CI: 0.40–0.77; I2 = 89%, p < 0.01), and the retrospective cohort study (RCS) group (OR: 0.64; 95% CI: 0.51–0.81; I2 = 87%, p < 0.01).ConclusionOur meta-analysis of 30 studies suggests that statin use may be associated with improved mortality and functional outcomes in patients with intracerebral hemorrhage (ICH).Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, CRD42023493063.…”
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An Evidence-Based Update on the Impact of Local Antimicrobials as Adjunct to Periodontal Therapy by Nabaz Yahya Hussein, Sadat Abdulla Aziz, Twana Mohammed M. Ways, Omed Amiri, Hisham Al-Obaidi, Dianne Ford

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Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study by Robert W Platt, Laurent Azoulay, Ying Cui, Christel Renoux, Oriana Hoi Yun Yu, Zarin Abdullah, Chenjie Xia

“…Objectives To assess the association between sodium-glucose co-transporter-2 inhibitor (SGLT-2i) use and the risk of incident dementia compared with dipeptidyl peptidase-4 inhibitors (DPP-4i) use among individuals with type 2 diabetes.Design A population-based retrospective cohort study.Setting The Clinical Practice Research Datalink (CPRD) Aurum database from the UK.Participants Individuals with type 2 diabetes, aged 40 years or older, newly prescribed SGLT-2i or DPP-4i on or after 2013–2021, registered in the CPRD Aurum database.Main outcome measure The primary outcome was incident dementia, and the secondary outcome was incident mild cognitive impairment (MCI). …”
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Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study by Changyu Jin, Zehong Lu, Yuzhan Chen, Huijie Hu, Miao Zhou, Yanli Zhang, Guifang Ouyang, Tongyu Li, Lixia Sheng

“…Methods A two-sample MR analysis assessed the impact of specific plasma proteins on CLL risk, using data from the Finngen Proteomics project (analyzing 828 participants) and the UK Biobank. Additional analyses included colocalization, phenomenon-wide MR, and protein–protein interaction networks. …”
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Validation of the Arabic Version of Asthma Numeracy Questionnaire (ANQ) Among Parents of Asthmatic Children: Factor and Rasch Analyses Study by Al-Qerem W, Jarab A, Al Bawab AQ, Eberhardt J, Alasmari F, Hammad A, Al-Zayadneh E, Al-Iede M, Al-sa’di L, Obidat R

“…Walid Al-Qerem,1 Anan Jarab,2– 4 Abdel Qader Al Bawab,1 Judith Eberhardt,5 Fawaz Alasmari,6 Alaa Hammad,1 Enas Al-Zayadneh,7 Montaha Al-Iede,7 Lujain Al-sa’di,1 Raghd Obidat1 1Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 11733, Jordan; 2College of Pharmacy, Al Ain University, Abu Dhabi, 112612, United Arab Emirates; 3AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, 112612, United Arab Emirates; 4Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan; 5Department of Psychology, School of Social Sciences, Humanities and Law, Teesside University, Middlesbrough, TS1 3BX, UK; 6Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 12372, Saudi Arabia; 7Department of Pediatrics, School of Medicine, University of Jordan, Amman, JordanCorrespondence: Walid Al-Qerem, Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 11733, Jordan, Email waleed.qirim@zuj.edu.joBackground: The increasing global prevalence of asthma necessitates effective disease management, with patients and their families playing a central role. …”
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Patient and public involvement in the co-design and assessment of unobtrusive sensing technologies for care at home: a user-centric design approach by Jenny Sharma, Nazia Gillani, Imran Saied, Aaesha Alzaabi, Tughrul Arslan

“…This study aims to explore the involvement of various stakeholders across different developmental stages to inform the design and assess the capabilities of unobtrusive sensing solutions being developed as part of the Advanced Care Research Centre (ACRC), Edinburgh, UK. Methods This study was conducted in two phases. …”
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Brief intervention to reduce fatigue impact in patients with inflammatory arthritis: design and outcomes of a single-arm feasibility study by Paul Ewings, Emma Dures, Sarah Hewlett, Joanna Thorn, Mwidimi Ndosi, Siobhan Creanor, Jo Adams, Lance M McCracken, Joe Lomax, Susan Bridgewater, Bryan Abbott, Alice Berry, Marie Urban

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Translation of a Diabetes Remission Service into Australian Primary Care: Findings from the Evaluation of DiRECT-Australia by Ritesh Chimoriya, Kimberly Mitlehner, Chee L. Khoo, Uchechukwu Levi Osuagwu, Russell Thomson, Lei Si, Michael Lean, David Simmons, Milan K. Piya

“…The Diabetes Remission Clinical Trial (DiRECT) study demonstrated that an intensive and structured weight management program in UK primary care resulted in high rates of diabetes remission in adults with recent onset type 2 diabetes mellitus (T2DM). …”
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Prevalence of diabetic retinopathy and its associated factors among adults in East African countries: A systematic review and meta-analysis. by Habtamu Wagnew Abuhay, Tigabu Kidie Tesfie, Meron Asmamaw Alemayehu, Muluken Chanie Agimas, Getaneh Awoke Yismaw, Gebrie Getu Alemu, Nebiyu Mekonnen Derseh, Bantie Getnet Yirsaw

“…<h4>Trial registration</h4>Systematic review registration: PROSPERO (2024: ID = CRD42024511437). https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024511437.…”
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Comparison of the safety of remimazolam and propofol during general anesthesia in elderly patients: systematic review and meta-analysis by Xianchun Liu, Longyi Zhang, Li Zhao, Xuelei Zhou, Wei Mao, Linlin Chen, Hongyu Zhu, Ying Xie, Linji Li

“…Remimazolam may be a safer sedative for elderly patients.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024516950, CRD42024516950.…”
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Association of physical and sexual assault with mortality in two British birth cohorts by Jayati Das-Munshi, Ioannis Bakolis, William Lee, Vishal Bhavsar, James H MacCabe

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Research hotspots and trends in lung cancer STAS: a bibliometric and visualization analysis by Xiuhua Peng, Hupo Bian, Hongxing Zhao, Dan Jia, Mei Li, Wenhui Li, Pengliang Xu

“…This study’s findings provide new insights and directions for future research in this area.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/#myprospero, identifier 589442.…”
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Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing by Maham Tanveer, Karina Klein, Brigitte von Rechenberg, Salim Darwiche, Hannah L. Dailey

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Gender differences in the price elasticity of demand for waterpipe and cigarette smoking in Lebanon, Jordan and Palestine: a volumetric choice experiment by Ramzi G Salloum, Mohammed Jawad, Aya Mostafa, Yousef Khader, Rima Nakkash, Niveen ME Abu-Rmeileh, Ali Chalak, Ruba Abla, Sameera Awawda

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Geochemistry and mineralogy of Cobalt in mine wastes: examples from Cobalt, Canada and Cornwall, England by Gabriel Ziwa, Gabriel Ziwa, Gabriel Ziwa, Rich Crane, Rich Crane, Karen A. Hudson-Edwards, Karen A. Hudson-Edwards

“…In this study, the geochemistry (bulk and sequential extraction analysis, paste pH) and mineralogy (X-ray diffraction, scanning electron microscopy, electron microprobe analysis) of Co in mine wastes from Cobalt (Canada) and Cornwall (UK) were characterised to assess potential Co and other metal(loid) mobility in the aquatic environment. …”
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Does interprofessional simulation increase self-efficacy: a comparative study by Peter Jaye, Gabriel Reedy, Alastair Ross, Colm Watters, Nicola J Morgan, Rhodri Handslip

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