Murine model of cross-IgE sensitization and cross-anaphylactic reactions among multiple group food allergens by Ibrahim Musa, Fariba Ardalani, Nan Yang, Soheila J. Maleki, Xiu-Min Li, Xiu-Min Li, Xiu-Min Li

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Insights into salinity effect on growth of the spotted scat (Scatophagus argus): Exploring the optimum salinity for its culture by Maoliang Su, Zhanquan Feng, Youling Zhong, Zhiyin Ye, Junbin Zhang

“…The results above indicated that there were energetic trade-offs between osmoregulation and somatic growth. A “U-shaped” relationship between salinity and final weight was revealed through regression analysis, and it was deduced that the optimal salinity for the growth of S. argus juveniles was 17.40 ppt. …”
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Association between sleep duration and hypertension in southwest China: a population-based cross-sectional study by Yu Guo, Liming Li, Zhengming Chen, Qiang Sun, Pei Pei, Xianping Wu, Ningmei Zhang, Xiaofang Chen, Guojin Luo, John S Ji, Xiaoyu Chang, Xiaofang Chen*

“…The odds of hypertension was relatively flat until around 6.81 hours of sleep duration and then started to increase rapidly afterwards in subjects and a J-shaped pattern was observed. There was a U-shaped relationship between sleep duration and hypertension in females.Conclusion Long sleep duration was significantly associated with hypertension and a J-shaped pattern was observed among rural adults in southwest China, independent of potential confounders. …”
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ＩｇＡ肾病患儿血浆氧化应激水平及早期联用ＡＣＥＩ的影响

“…【结果】 ①与对照组相比，ＩｇＡＮ组血浆氧化应激水平明显升高，表现为ＡＯＰＰ和ＭＤＡ水平明显升高［ＡＯＰＰ：（９９ ± ２７） ｖｓ （５３ ± ２１）μｍｏｌ／ｍＬ，ＭＤＡ：（５．３ ± ２．１） ｖｓ （２．５ ± １．４） ｎｍｏｌ／ｍＬ，均Ｐ ＜ ０．０１］，ＳＯＤ水平明显下降［（６７ ± ２１） ｖｓ （９５ ± ２０）Ｕ／ｍＬ，Ｐ＜ ０．０１］。②血浆氧化应激水平在肾病综合征组和病理Ｖ级组最高，且与ＩｇＡＮ患儿的肾脏Ｋａｔａｆｕｃｈｉ评分密切相关。…”
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Restricción del crecimiento intrauterino y peso del cerebro en relación con sus órganos vitales en lechones neonatos: consideraciones para la producción porcina by A. ROMANELLI, J.M. DECUNDO, G. MARTÍNEZ, M.B. FERNANDEZ PAGGI, D.S. PÉREZ GAUDIO, S.N. DIEGUEZ, A. L. SORACI

“…Se los clasificó como lechones normo peso (>1 kg), bajo peso (<1 kg) y restringidos (<1 kg y con cabezas tamaño relativo mayor que su cuerpo con forma semejante a un foco, exoftalmia u ojos saltones y hocico arrugado con pliegues perpendiculares a la boca). …”
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TSH Variability of Patients Affected by Differentiated Thyroid Cancer Treated with Levothyroxine Liquid Solution or Tablet Form by Carlo Cappelli, Ilenia Pirola, Elena Gandossi, Claudio Casella, Davide Lombardi, Barbara Agosti, Fiorella Marini, Andrea Delbarba, Maurizio Castellano

“…Recent guidelines from the American Thyroid Association (ATA) indicate that, in many patients affected by differentiated thyroid cancer (DTC), the serum TSH should be maintained between 0.1 and 0.5 mU/L. The purpose of this study was to evaluate the TSH variability of patients affected by DTC treated with liquid L-T4 formulation or in tablet form. …”
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Effects of cassava pellets and enzymes addition on growth performance, meat quality, serum biochemical indices and cecum microbiota of broilers by Dan Yue, Ying Lu, Jin Zhao, Xiaoming He, Junhong Zhu, Jiawei Liang, Weidong Deng

“…A total of 144 healthy 1-day-old AA broilers were randomly assigned to six dietary groups: basal diet (K1), basal diet + 5 % cassava pellets (K2), basal diet + 10 % cassava pellets (K3), basal diet + 20 % cassava pellets (K4), basal diet + 20 % cassava pellets + 0.3 % tannase (K5), and basal diet + 20 % cassava pellets + 0.3 % tannase + 2500 U/kg α-amylase (K6). At 21 days, growth performance, meat quality, serum biochemical indices, and cecal microbial composition were analyzed. …”
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Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Sign... by Jingjing Ye, Wei Ai, Fenglin Zhang, Xiaotong Zhu, Gang Shu, Lina Wang, Ping Gao, Qianyun Xi, YongLiang Zhang, Qingyan Jiang, Songbo Wang

“…Moreover, Ca2+o-induced promotion of pBMSCs proliferation, the changes of proliferative genes expression levels, and the activation of ERK1/2 signaling pathway were effectively blocked by U0126, a selective ERK kinase inhibitor. In conclusion, our findings provided evidence that the enhanced pBMSCs proliferation in response to Ca2+o was associated with the activation of CaSR and ERK1/2 signaling pathway, which may be useful for the application of pBMSCs in future clinical studies aimed at tissue regeneration and repair.…”
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Optimal vocal therapy for respiratory muscle activation in patients with COPD: effects of loudness, pitch, and vowels by Zhengtong Qiao, Ziwei Kou, Jiazhen Zhang, Daozheng Lv, Dongpan Li, Xuefen Cui, Kai Liu

“…However, variations in singing treatment protocols have led to inconsistent clinical outcomes.ObjectiveThis study aims to explore the content of vocalization training for patients with COPD by observing differences in respiratory muscle activation across different vocalization tasks.MethodsAll participants underwent measurement of surface electromyography (sEMG) activity from the sternocleidomastoid (SCM), parasternal intercostal muscle (PARA), seventh intercostal muscle (7thIC), and rectus abdominis (RA) during the production of the vowels/a/,/i/, and/u/at varying pitches (comfortable, +6 semitones) and loudness (−10 dB, +10 dB) levels. …”
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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…The RCS analysis indicated a U-shaped nonlinear relationship between HbA1c levels and all-cause mortality (P = 0.026 for nonlinearity) and a J-shaped nonlinear relationship with CVD mortality (P = 0.035 for nonlinearity).ConclusionThis cohort study suggests that both low and high HbA1c levels are associated with an increased risk of all-cause mortality in elderly patients with non-diabetic CKD.…”
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Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area by Girma Tariku, Isabella Ghiglieno, Andres Sanchez Morchio, Luca Facciano, Celine Birolleau, Anna Simonetto, Ivan Serina, Gianni Gilioli

“…We conducted a comparative study, using cutting-edge deep-learning-based segmentation models (U-Net, SegNet, DeepLabV3) with various pre-trained backbones (ResNet, Inception, DenseNet, EfficientNet) on our dataset acquired from Google Earth Pro. …”
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Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a p... by Ziyu Weng, Chenzhong Wang, Bo Liu, Yi Yang, Yueqi Zhang, Chi Zhang

“…Results In this study, we identified three hub genes: interleukin 1 receptor-associated kinase 3 (IRAK3), integrin subunit beta-like 1 (ITGBL1), and Ras homolog family member U (RHOU). An Artificial Neural Network (ANN) diagnostic model constructed based on these hub genes demonstrated excellent performance in both training and validation phases. …”
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Neurocognitive impact of different irradiation modalities for patients with grade I-II skull base meningioma: a prospective multi-arm cohort study (CANCER COG) by Paul Lesueur, Florence Joly, Benedicte Clarisse, Justine Lequesne, Dinu Stefan, Jacques Balosso, Marie Lange, Sebastien Thureau, Aurelie Capel, Marie Castera, Berenice Legrand, Nicolas Goliot, Jean Michel Grellard, Thomas Tessonier, Helene Castel, Samuel Valable

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RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression by Yihui Ma, Enjie Liu, Huijie Fan, Chenfei Li, Pei Huang, Meiying Cui, Zhengyang Wang, Jing Zhou, Kuisheng Chen

“…Loss- and gain-of-function effects of RBM47 on cell proliferation, tumor growth, and immune evasion were determined by CCK-8, EdU incorporation, colony formation assays, the xenogeneic tumor model, and co-culture system of PC and NK-92 cells. …”
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The Impact of Carbon on Electronic Structure of N-Doped ZnO Films: Scanning Photoelectron Microscopy Study and DFT Calculations by Elzbieta Guziewicz, Sushma Mishra, Matteo Amati, Luca Gregoratti, Oksana Volnianska

“…Generalized Gradient Approximation (GGA) supplemented by +U correction was applied to both <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>Z</mi><mi>n</mi><mn>3</mn><mi>d</mi></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>O</mi><mn>2</mn><mi>p</mi></mrow></semantics></math></inline-formula> orbitals for calculation of the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>V</mi><mi>Zn</mi></msub></semantics></math></inline-formula> migration properties by the Nudged Elastic Band (NEB) method. …”
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Uncovering molecular mechanisms of soybean response to 12C6+ heavy ion irradiation through integrated transcriptomic and metabolomic profiling by Honglei Ren, Bixian Zhang, Chunlei Zhang, Xiulin Liu, Xueyang Wang, Fengyi Zhang, Kezhen Zhao, Rongqiang Yuan, Ahmed M. Abdelghany, Sobhi F. Lamlom

“…A total of 1500 rounds of disease-free soybean seeds underwent irradiation with 270 MeV/u 12C6+ ion beams, administered at doses of 0, 120, and 150 Gy. …”
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Purine metabolites regulate leukemic cell sensitivity toward cytarabine by Xiaowen Zhang, Ang Jia, Jianwei You, Zixuan Zhuang, Yinfei Wang, Ting Liu, Xingrong Du, Linzhang Huang, Peng Li, Tong-Jin Zhao, Craig T. Jordan, Li Chen, Ji-Hao Zhou, Haobin Ye

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Interaction Between Malat1 and miR-499-5p Regulates Meis1 Expression and Function with a Net Impact on Cell Proliferation by Salma A. Fahim, Manon Ragheb, Ibrahim Hassan Fayed, Aya Osama, Ahmed Karam, Sameh Magdeldin, Rana Metwale, Mohamed Dief Allah Abdalmoneam Elsayed, Ahmed Abdellatif, Hesham A. Sadek, Shereen Ahmed El Sobky, Nada El-Ekiaby, Injie Omar Fawzy, Ahmed Ihab Abdelaziz

“…Moreover, knocking down Malat1 increased miR-499-5p expression, subsequently suppressing Meis1. Through BrdU incorporation assay, we showed that the knockdown of Malat1, Meis1, or mimicking with miR-499-5p promoted cell proliferation. …”
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New Insights on <i>Gordonia alkanivorans</i> Strain 1B Surface-Active Biomolecules: Gordofactin Properties by João Tavares, Susana M. Paixão, Tiago P. Silva, Luís Alves

“…The most purified sample, designated as extracted gordofactin, after lyophilization, presented a specific emulsifying activity of 9.5 U/mg and a critical micelle concentration of 13.5 mg/L. …”
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Selectively expressed RNA molecules as a versatile tool for functionalized cell targeting by Frederik Rastfeld, Marco Hoffmann, Sylvie Krüger, Patrick Bohn, Anne-Sophie Gribling-Burrer, Laura Wagner, Nils Hersch, Carina Stegmayr, Lukas Lövenich, Sven Gerlach, Daniel Köninger, Christina Hoffmann, Helene L. Walter, Dirk Wiedermann, Hajaani Manoharan, Gereon R. Fink, Rudolf Merkel, Heribert Bohlen, Redmond P. Smyth, Maria A. Rueger, Bernd Hoffmann

“…We effectively treat breast tumor cell clusters in mixed cell systems and shrink early U87 glioblastoma cell clusters in the brain of male mice without detectable side effects. …”
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