Xiaoyao Pills Attenuate Inflammation and Nerve Injury Induced by Lipopolysaccharide in Hippocampal Neurons In Vitro by Yang Fang, Boyu Shi, Xiaobo Liu, Jie Luo, Zhili Rao, Rong Liu, Nan Zeng

“…Xiaoyao Pills significantly decreased the levels of IL-6, TNF-α, and IDO in cell supernatant and increased the expression of BDNF, NGF, TrkB, TrkA, CREB, p-CREB, p-CREB/CREB, and SYP as well as the average optical density of BrdU/NeuN double-labelled positive cells. Our study shows that lipopolysaccharides induce inflammation and nerve damage in hippocampal neurons, which are closely related to the pathological mechanism of depression. …”
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تأثیر تمرین ورزشی بر میزان آپلین سرمی و مقاومت به انسولین در بیماران مبتلا به دیابت نوع 2: مرور نظام‌مند و فراتحلیل... by فاطمه کاظمی نسب, نفیسه حسن پور, امید ظفرمند

“…با این وجود، تجزیه و تحلیل داده­­ها نشان داد که تمرین ورزشی سبب کاهش معنادار سطوح گلوکز ناشتا ]001/0P= ،(37/26- الی 69/11-)mg/dl  034/19-=[WMD، میزان انسولین ناشتا ]001/0P= ،(429/5- تا 804/1-)mU/mL  616/3-= [WMDو شاخص مقاومت به انسولین یا HOMA-IR ]001/0P= ،(044/2- تا 104/1-) 574/1-= [WMD نسبت به گروه کنترل در بیماران T2DM شد. …”
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hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p by Shenglan Huang, Kan Liu, Yongkan Xu, Hua Wang, Shumin Fu, Jianbing Wu

“…Further functional assays, including CCK8, EdU, colony formation assays, scratch-healing, transwell assays, and Xenograft tumor models were conducted to explore the biological functions of circPTK2. …”
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Self-compassion and work engagement among clinical nurses: the mediating role of moral resilience by Xingxing Liu, Fang He, Tian Tian, Jun Zhang, Yuanjiao Ji, Yuexia Zhong

“…The data analysis involved descriptive statistics, the Mann–Whitney U test, the Kruskal-Wallis H rank-sum test, Spearman correlation analysis, and the SPSS PROCESS macro.ResultsA significant positive correlation was observed between clinical nurses’ self-compassion and moral resilience (r = 0.700, p < 0.01). …”
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Challenges and opportunities for data integration to improve estimation of migratory connectivity by Jeffrey A. Hostetler, Emily B. Cohen, Christen M. Bossu, Amy L. Scarpignato, Kristen Ruegg, Andrea Contina, Clark S. Rushing, Michael T. Hallworth

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Characteristics of velopharyngeal dysfunction in 22q11.2 deletion syndrome: a retrospective case-control study by Sebastiano Failla, Peng You, Chandheeb Rajakumar, Anne Dworschak-Stokan, Philip C. Doyle, Murad Husein

“…Results Lateral pharyngeal wall displacement was found to be reduced in the 22q11.2 deletion syndrome group (U = 29.50, p = .001, r = .63). However, measures of velar displacement were not observed to differ between groups. …”
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Silencing of STEAP3 suppresses cervical cancer cell proliferation and migration via JAK/STAT3 signaling pathway by Zouyu Zhao, Panpan Yu, Yan Wang, Hong Li, Hui Qiao, Chongfeng Sun, Lina Zhu, Ping Yang

“…Cell viability, proliferation, migration, and invasion, were evaluated using the Cell Counting Kit-8 (CCK8), 5-ethynyl-2’-deoxyuridine (EdU), wound repair assay, and transwell assay, respectively. …”
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System aukcyjny jako nowy sposób wspierania OZE by Waldemar Gostomczyk

“…Materiałem badawczym były materiały statystyczne Eurostatu i GUS-u, dokumenty Komisji Europejskiej, Ministerstwa Energii, Urzędu Regulacji Energetyki, raporty dotyczące systemów wsparcia z krajów europejskich i Polski. …”
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Implementing the Kids’ Athletics Program in the System of Increasing the Level of Physical Performance of Youth by Ján Jakubík, Jaroslav Broďáni

“…The effectiveness of the 7-month experimental program was evaluated using comparative analysis through non-parametric statistical methods: Wilcoxon and Mann-Whitney U test and substantive significance assessment: Cohen (r). …”
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Stimulation of Alpha7 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Upregulation of MMP, MCP-1, and RANTES through Modulating ERK1/2/AP-1 Signaling Pathway in RAW264... by Liping Liu, Hongxian Wu, Qunan Cao, Zhenzhen Guo, Anmin Ren, Qiuyan Dai

“…Nicotine markedly stimulated the phosphorylation of extracellular signal-regulated kinase1/2 (ERK1/2) and c-Jun in RAW264.7 cells. Pretreatment with U0126 significantly suppressed phosphorylation of ERK1/2 and further attenuated nicotine-induced activation of c-Jun and upregulation of MMP-2, MMP-9, monocyte chemotactic protein- (MCP-) 1, and regulated upon activation normal T cell expressed and secreted (RANTES). …”
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Chromothripsis in Treatment Resistance in Multiple Myeloma by Kyoung Joo Lee, Ki Hong Lee, Kyong-Ah Yoon, Ji Yeon Sohn, Eunyoung Lee, Hyewon Lee, Hyeon-Seok Eom, Sun-Young Kong

“…First, we analyzed nine MM cell lines (U266, MM.1S, RPMI8226, KMS-11, KMS-12-BM, KMS-12-PE, KMS-28-BM, KMS-28-PE, and NCI-H929) and bone marrow samples of four patients who were diagnosed with MM by next-generation sequencing-based copy number variation analysis. …”
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Green space is associated with new-onset stroke among Chinese middle-aged and older adults: data from China Health and Retirement Longitudinal Study (CHARLS) by Qiong Lu, Qiong Lu, Cheng Lian, Xinglin Chen, Xinglin Chen

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Inhibition of Glutamine Uptake Improves the Efficacy of Cetuximab on Gastric Cancer by Huanrong Ma PhD, Jingjing Wu Bachelor, Minyu Zhou PhD, Jianhua Wu PhD, Zhenzhen Wu PhD, Li Lin PhD, Na Huang PhD, Wangjun Liao PhD, Li Sun PhD

“…Consistent with previous studies, it was shown herein by MTT and EdU assays that cetuximab had a weak inhibitory effect on the cell viability of gastric carcinoma cells. …”
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Resiliência da progressividade, da capacidade contributiva e da redistribuição de renda na tributação das pessoas físicas em época de crise – um estudo objetivado na crise financei... by João Ricardo Catarino, Maria Adosinda Teixeira

“…Adota-se como estudo de caso a reforma do imposto de renda na recente crise financeira portuguesa (2008 a 2012), durante a qual foi parcialmente executado o Memorando de Entendimento sobre as Condicionantes de Política Econômica (Memorando da Troika ou MoU – Memorandum of Understanding), no qual Portugal assumiu a obrigação de realizar um enorme esforço de consolidação fiscal e sustentabilidade financeira das contas públicas a longo prazo pela via da receita tributária. …”
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İşletmelerin Malmquist-TFV Endeksi İle Verimliliklerinin Analizi: Tekstil Sanayi Örneği by Vural Çağlıyan, Emel Gelmez, Ramazan Göral

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Ranibizumab for Visual Impairment due to Diabetic Macular Edema: Real-World Evidence in the Italian Population (PRIDE Study) by Ugo Menchini, Francesco Bandello, Vincenzo De Angelis, Federico Ricci, Luigi Bonavia, Francesco Viola, Elisa Muscianisi, Massimo Nicolò

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Stability and Control of Surrounding Rock of a Trapezoidal Roadway Retained with Hard Roof Cutting by Shizhong Zhang, Chuangnan Ren, Xinyao Gao, Yongsheng Gao, Lianyi Nie, Shaodong Li, Moulie Jiang

“…Using top-cutting, the pressure relief reduced the roof stress from 6.73 MPa to 2.04 MPa, the high stress zone moved to the inside of the solid coal, and the roof slid and deformed along the top line, showing characteristics of a “large deformation on the top side”; and (3) high-strength long anchor cables were used to reinforce the roof on the cut top side. Telescopic U-shaped steel and windshield cloth were used to block gangue and prevent wind leakage in the roadway. …”
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Intraspecific Morphometric Variation in a New Species of <i>Ceratomyxa</i> Thélohan 1892 (Cnidaria) from the South Atlantic Ocean: An Ecomorphological Study Using Geometric Morphom... by Delfina M. P. Cantatore, Martina Lisnerová, Paula S. Marcotegui, María A. Rossin, Astrid S. Holzer

“…This study is the first to apply landmark-based geometric morphometrics (GM) in myxozoan research, providing a detailed analysis of conspecific morphometric variation of ceratomyxid myxospores, examining their natural variation within and among different ceratomyxids infecting the gall bladder of <i>U. canosai</i>. Using GM analyses, we successfully capture and quantify phenotypic variation at the organismal level. …”
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Patient Perspectives on Personalized Risk Communication Using Polygenic Risk Scores to Inform Colorectal Cancer Screening Decisions by Shauna R. Goldberg, MPH, Linda K. Ko, PhD, Li Hsu, PhD, Hang Yin, MS, Charles Kooperberg, PhD, Ulrike Peters, PhD, MPH, Andrea N. Burnett-Hartman, PhD, MPH

“…Introduction: Colorectal cancer is increasingly diagnosed in people aged <50 years. New U.S. guidelines recommend screening initiation at age 45 years. …”
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Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Pr... by Leake Gebrargs, Bereket Gebremeskel, Bacha Aberra, Assefa Hika, Yusuf Yimer, Misrak Weldeyohannes, Suleiman Jemal, Degena Behrey, Abere Tilahun

“…Continuous data of independent and dependent variables were analyzed using an independent sample t-test for normally distributed and Mann–Whitney U-test for nonnormally distributed between the study groups. …”
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