PTPN2 Downregulation Is Associated with Albuminuria and Vitamin D Receptor Deficiency in Type 2 Diabetes Mellitus by Li Zheng, Wei Zhang, Aimei Li, Yan Liu, Bin Yi, Farid Nakhoul, Hao Zhang

“…Methods. 101 T2DM patients were divided into three groups based on urinary albumin-to-creatinine ratio (uACR): normal albuminuria (uACR < 30 mg/g, n=29), microalbuminuria (30 mg/g ≤ uACR < 300 mg/g, n=34), and macroalbuminuria (uACR ≥ 300 mg/g, n=38). …”
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Markers of Glomerular and Tubular Damage in the Early Stage of Kidney Disease in Type 2 Diabetic Patients by Agnieszka Żyłka, Paulina Dumnicka, Beata Kuśnierz-Cabala, Agnieszka Gala-Błądzińska, Piotr Ceranowicz, Jakub Kucharz, Anna Ząbek-Adamska, Barbara Maziarz, Ryszard Drożdż, Marek Kuźniewski

“…Among 80 T2DM patients with median eGFR of 92.4 ml/min/1.73 m2 and median urinary albumin to creatinine ratio (uACR) of 4.69 mg/g, 19 had uACR > 30 mg/g (A2). …”
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GÖZTEPE PROF. DR. SÜLEYMAN YALÇIN ŞEHİR HASTANESİ’NDE 2016-2022 YILLARI ARASINDA İZOLE EDİLEN SERRATIA MARCESCENS SUŞLARINDA ANTİBİYOTİK DİRENCİ by Bilal Demirtaş, İrem Şahin, Esma Tekin, Tecem Özdemir, Sevda Bayat, Çisil Doğa Ünal, Fadime Meryem Özdoğan, Tuncer Özekinci, Zeynep Aydoğan Cihan

“…S. marcescens %42 oranıyla en çok üriner sistem örneklerinde izlenmiş, %20’si trakeal aspirat örneklerinden, %13’ü kan kültüründen, %10’u apse aspiratı ve yara sürüntüsü örneklerinden, %5’i balgam, %4’ü doku, %3’ü kateter, %2’si bronkoalveolar lavaj ve %1’i diğer örneklerden izole edilmiştir.Çalışmamızda izole edilen S. marcescens suşlarının en duyarlı olduğu antibiyotiklerin aminoglikozit grubu antibiyotiklerden amikasin (&gt;%98) ve gentamisin (&gt;%96), karbapenemlerden meropenem (&gt;%98) ve ertapenem (&gt;%97) olduğu saptanmıştır. …”
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The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats by Murat Olukman, Cenk Can, Sibel Ülker, Yiğit Uyanikgil, Türker Çavuşoğlu, Neslihan Düzenli, Deniz Coşkunsever, Fatma G. Kozcu

“…Although induction of diabetes did not change U-II expression in CC significantly, palosuran treatment reduced U-II expression in diabetic CC. …”
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Diagnostic disparities in inborn errors of immunity: From clinical suspicion to diagnosis by Karen M. Gilbert, PhD, Robert F. LeCates, MA, Alison A. Galbraith, MD, MPH, Paul J. Maglione, MD, PhD, Stephanie Argetsinger, MPH, Nicholas L. Rider, DO, Jocelyn R. Farmer, MD, PhD, Mei-Sing Ong, PhD

“…Participants included patients diagnosed with an “unspecified immune deficiency” (uID) and presented with IEI-related symptoms, who later received an IEI diagnosis (n = 1429). …”
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Emergence and polyclonal dissemination of NDM-5/OXA-181 carbapenemase-producing Escherichia coli in the French Indian Ocean territories by Thibaut Vedani, Matthieu Pot, Thomas Garrigos, Loïk Sababadichetty, Marion Daniel, David Wilkinson, Thierry Benoit-Cattin, Olivier Belmonte, Patrick Mavingui, Laurent Dortet, Guillaume Miltgen

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Bullatine A suppresses glioma cell growth by targeting SIRT6 by Zhi Wang, Yushuai Zhu, Can Luo, Fan Zhang, Jiannong Zhao, Chuanyi Fu

“…Our results showed that BLA inhibited the proliferation of U87MG and U251 cells in a dose-dependent manner and decreased their survival rate. …”
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The internal conflicts and contemporary dilemmas of America’s national characteristics by Shaoqing Zhou

“…With the continuous decline in the population of the white majority, this balance is likely to break down further, potentially resulting in prolonged internal strife within the U.S.…”
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A polysaccharide-based hydrogel platform for tumor spheroid production and anticancer drug screening by Elliot Lopez-Vince, Teresa Simon-Yarza, Claire Wilhelm

“…This platform was validated for drug testing using three cancer cell lines (A673, MCF7 and U87) and 2 anticancer drugs (doxorubicin and paclitaxel). …”
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Comparative studies on the intramuscularly injections of different regions in dogs by Sadettin TIPIRDAMIAZ, Nuri YAVRU, Kadircan ÖZKAN

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Real Flight Application of a Monocular Image-Based Aircraft Collision Decision Method by Peter Bauer, Antal Hiba, Tamas Zsedrovits

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Improvements of particle filter optimization algorithm for robust optimization under different types of uncertainties by Éva Kenyeres, Alex Kummer, János Abonyi

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Quantitative analysis of the effect of microtubule-targeting drugs on the microtubule cytoskeleton of breast cancer cells with different invasive properties by Michallet, Sophie, Bosc, Lauriane, Lafanechère, Laurence

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Haematological and Biochemical Studies on some Ruminants by LC Chuku, AA Uwakwe

“…Only the ‘O’ Rh blood group was observed in all cases, and GST values of 4.05-6.30 I.U were obtained on the other hand. Cow Hb electrophoresis produced two patterns corresponding to the human HbAA and HbAS types. …”
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A Simple Formula for Local Burnup and Isotope Distributions Based on Approximately Constant Relative Reaction Rate by Cenxi Yuan, Xuming Wang, Shengli Chen

“…Based on these considerations, the formula is obtained to calculate the reaction rates of 235U, 238U, and 239Pu and straightforward the local burnup and the isotope distributions. …”
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The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPARγ-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells by Adrienne Bolden, Lynikka Bernard, Danielle Jones, Tunde Akinyeke, LaMonica V. Stewart

“…Troglitazone-induced increases in Erk phosphorylation were suppressed by the MEK inhibitor U0126 but not by the PPARγ antagonist GW9662. Pretreatment with U0126 did not alter the ability of troglitazone to regulate expression of two proteins that control cell cycle, p21, and c-Myc. …”
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Social media and students' learning by Marković Marija, Stanisavljević-Petrović Zorica

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