Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants by Nikos Stratakis, Augusto Anguita-Ruiz, Lorenzo Fabbri, Léa Maitre, Juan R. González, Sandra Andrusaityte, Xavier Basagaña, Eva Borràs, Hector C. Keun, Lida Chatzi, David V. Conti, Jesse Goodrich, Regina Grazuleviciene, Line Småstuen Haug, Barbara Heude, Wen Lun Yuan, Rosemary McEachan, Mark Nieuwenhuijsen, Eduard Sabidó, Rémy Slama, Cathrine Thomsen, Jose Urquiza, Theano Roumeliotaki, Marina Vafeiadi, John Wright, Mariona Bustamante, Martine Vrijheid

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Power Transmission for Millimeter-Wave Indoor/Outdoor Wearable IoT Devices Using Grounded Coplanar Waveguide-Fed On-Body Antenna by Fuad Erman, Slawomir Koziel, Alhareth Zyoud, Leifur Leifsson, Ubaid Ullah, Shaker Alkaraki

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Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells by Caitlin M. Tressler, Kanchan Sonkar, Menglin Cheng, Vinay Ayyappan, Ruoqing Cai, Kristine Glunde

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Takdim by Halil Burak Sakal, Merve Yildiz

“…Yüzyıl İç Anadolu’sunda bir Osmanlı köyü olan Sinason’u ele almaktadır. Köyün, 1696 ile 1782 yılları arasına tarihlenen on arşiv belgesi üzerinden kendine özgü idari, sosyo-ekonomik ve hukuki dinamiklerini ortaya koymaktadır. …”
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Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies by Sara M. Robledo, Wilson Cardona, Karen Ligardo, Jéssica Henao, Natalia Arbeláez, Andrés Montoya, Fernando Alzate, Juan M. Pérez, Victor Arango, Iván D. Vélez, Jairo Sáez

“…(V.) panamensis (EC50 17.0 + 2.8 mg/mL, 53.7 μM) and low toxicity on mammalian U-937 cells, with an index of selectivity >11.8. …”
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AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can... by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

“…The potential functions of AGD1 and METTL13 in CRPC were investigated through cell proliferation assay, Transwell assay, EdU incorporation assays, Annexin V-FITC/PI staining, and sphere formation assays. …”
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Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset by Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Sung Hyun Lee, Chul Park

“…Methods We developed an automated lumbar spine slice classification model using the CNN (EfficientNetV2) algorithm and an automated domain segmentation model to identify the subcutaneous fat, visceral fat, and muscle areas using the U-NET algorithm. These models were used to identify L3 slices from abdominal computed tomography images and divide the images into the three-segmented domains for sarcopenia diagnosis. …”
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Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block by Shobhit Shah, Monika Bhandari, Pravesh Vishwakarma, Wahid Ali, Mohammad Kaleem Ahmad, Abhishek Singh, Ayush Shukla, Akhil Kumar Sharma, Gaurav Chaudhary, Akshyaya Pradhan, Sharad Chandra, Rishi Sethi, S. K. Dwivedi

“…The mean serum total antioxidant capacity (U/ml) for the patients was 5.546 ± 0.620, whereas the controls had a mean value of 8.346 ± 2.781 (P = 0.025). …”
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Clinicodemographic profile and predictors of poor outcome in hospitalised COVID-19 patients: a single-centre, retrospective cohort study from India by Prashant K Singh, Lokesh Tiwari, Alok Ranjan, Prakriti Gupta, Prabhat Kumar Singh, Yogesh Kumar, Yankappa N, Amrita Banerjee, C M Singh

“…Covariables were known comorbidities, clinical features, vital signs at the time of admission and on days 3–5 of admission, and initial laboratory investigations.Results Intergroup differences were tested using χ2 or Fischer’s exact tests, Student’s t-test or Mann-Whitney U test. Predictors of mortality were evaluated using multivariate logistic regression model. …”
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Exploring the Dynamics of Brent Crude Oil, S&P500 and Bitcoin Prices Amid Economic Instability by Adela Bara, Irina Alexandra Georgescu, Simona-Vasilica Oprea, Marian Pompiliu Cristescu

“…Additionally, to prove the robustness of the GARCH models, we further consider the West Texas Intermediate (WTI) and Dubai oil prices that are the dominant in the U.S and Asian market. The investigation identifies the TGARCH(1,1) Skewed Student model as the optimal choice among 9 models considered for VaR estimation. …”
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Automatic MRI Lymph Node Annotation From CT Labels by Souraja Kundu, Yuji Iwahori, M. K. Bhuyan, Manish Bhatt, Boonserm Kijsirikul, Aili Wang, Akira Ouchi, Yasuhiro Shimizu

“…The translation-based registration model for the algorithm’s first and third steps uses a discriminator-free StyleGAN2 translation network and a deformable image registration network with a U-Net-inspired architecture. This registration network includes local and global feature extraction modules, a local-global spatial correlation module, and a superresolution loss function. …”
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Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data by Luyang Su, Ren Xu, Yanan Ren, Shixia Zhao, Weilan Liu, Zeqing Du

“…This study aimed to evaluate the adverse events (AEs) associated with MPA in by analyzing real-world data from the U.S. Food and Drug Administration’s Adverse Event Reporting System (FAERS). …”
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A refined kidney tumor nephrometry system employed to screen pediatric patients who are eligible for nephron sparing surgery by Mingchuan Huang, Yingchun Fei, Zhihai Zhong, Hong Jiang, Longshan Liu, Juncheng Liu, Huanxi Zhang, Jun Li, Zhe Xu, Pengfei Gao, Pengfei Gao, Changxi Wang, Changxi Wang, Changxi Wang

“…We develop a refined nephrometry system based on a comprehensive understanding of the characteristics exhibited by pediatric kidney tumors.MethodsThe TUMORS nephrometry scoring system comprises 6 indicators, including tumor (T)hrombus, (U)rinary collecting system involvement, (M)ultiple tumors, (O)utward property, (R)adius, and (S)ite relative to the polar lines. …”
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Distressed Communities Index in Patients Undergoing Transcatheter Aortic Valve Implantation in an Affluent County in New York by Thomas Bilfinger, Allison Nemesure, Robert Pyo, Jonathan Weinstein, Giridhar Korlipara, Daniel Montellese, Shamim Khan, Neal Patel, Henry Tannous, Ting-Yu Wang, Ely Gracia, Susan Callahan, Puja B. Parikh

“…The clinical impact of the distressed communities index (DCI), a composite measure of economic well-being based on the U.S. zip code, is becoming increasingly recognized. …”
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Electrodermal activity and skin temperature characteristics related to stress and depression: A 4-week observational study of office workers by Yuki Ishikawa, Tatsuki Sugio, Kiko Shiga, Keisuke Izumi, Kazumichi Minato, Momoko Kitazawa, Sayaka Hanashiro, Ryo Takemura, Hiroyuki Uchida, Taishiro Kishimoto

“…The associations between electrodermal activity, skin temperature, and depressive/stress states were analyzed using the Mann–Whitney U test and logistic regression analysis. Results: Participants with PHQ-9 scores ≥5 showed higher median skin conductance and median tonic signal, although these differences lost statistical significance after Bonferroni correction. …”
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circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4 by Yunfei Wang, Taowei Yang, Qihao Li, Zhousan Zheng, Lican Liao, Junjie Cen, Wei Chen, Junhang Luo, Yi Xu, Mi Zhou, Jiaxing Zhang

“…High circASAP1 expression was associated with ccRCC cell proliferative viability, invasion, and metastasis in CCK-8, transwell, plate cloning, and EdU experiments. Interaction of circASAP1 with HNRNPC and their downstream target genes was confirmed by RNA pull-down, RNA immunoprecipitation, FISH, silver staining, and mass spectrometry. …”
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Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndrome by Zhixiao Xu, Xiong Lei, Weiwei Chu, Luoqi Weng, Chengshui Chen, Chengshui Chen, Chengshui Chen, Ran Ye

“…Nonetheless, the correlation between OBS and MetS displays variability within distinct cohorts.ObjectiveWe worked on the relationships between OBS and the risk of MetS, MetS severity, and all-cause mortality of MetS patients.MethodsA total of 11,171 adult participants were collected from the U.S. National Health Examination Survey (NHANES) 2007-2018. …”
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Detecting respiratory impairment in newly diagnosed rheumatoid arthritis by MRC dyspnoea scale and microfibrillar-associated protein 4 by Bjørk K. Sofiudottir, Sören Möller, Robin Christensen, Stefan Harders, Grith L. Sørensen, Jesper Blegvad, Mette Herly, Dzenan Masic, Grazina Urbonaviciene, Frank Andersen, Christin Isaksen, Brian Bridal Løgstrup, Charlotte Hyldgaard, Torkell Ellingsen

“…For MRC score ≥ 2, the sensitivity was 39.0% (95% CI 26.5; 52.6), specificity 76.4% (95% CI 64.9; 85.6), and DOR 2.07 (95% CI 0.97; 4.40). For MFAP4 > 29.0 U/mL, the sensitivity was 62.7% (95% CI 49.1; 75.0), specificity 56.9% (95% CI 44.7; 68.6), and DOR 2.22 (95% CI 1.10; 4.50). …”
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CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis by Hong-Fei Yao, Jieqiong Ge, Jiahao Chen, Xiaoyan Tang, Chunjing Li, Xiao Hu, Abousalam Abdoulkader Ahmed, Yunlong Pu, Guihua Zhou, Tongyi Zhang, Zhiwei Cai, Chongyi Jiang

“…Cells with CASC8 knockdown and overexpression were subjected to cell viability, EdU, transwell assays, and used to establish subcutaneous and orthotopic tumor models. …”
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Effects of soil water on fungal community composition along elevational gradients on the northern slope of the Central Kunlun Mountains by Yongguang Zhang, Yongguang Zhang, Chaonan Li, Zhihao Zhang, Chenhong Li, Bo Zhang, Hongchen Jiang, Waqar Islam, Xiangzhen Li, Fanjiang Zeng

“…Results indicated that the dominant phyla identified across the seven elevational gradients were Basidiomycota and Ascomycota, displaying a unimodal pattern and a U-shaped pattern in relative abundance, respectively. …”
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