Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album by A. B. Beklemishev, M. B. Pykhtina, Ya. M. Kulikov, T. N. Goryachkovskaya, D. V. Bochkov, S. V. Sergeeva, A. R. Vasileva, V. P. Romanov, D. S. Novikova, S. E. Peltek

“…The resulting recombinant protease has a high specific proteolytic activity: ~5000 U/mg.…”
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Effects of tongue tamers and customized bonded spurs as an early treatment of anterior open bite: a randomized clinical study by Safa B. Alawy, Shaimaa S. EL-Desouky, Ibrahim A. Kabbash, Shimaa M. Hadwa

“…Regarding SNB measurement, there was a non-significant increase in all three groups with the highest increase in group-I(0.49 ± 0.48) followed by group-III(0.34 ± 0.63). The U1/FHP and L1/GoGn angles were non-significantly decreased in all tested groups with the highest decrease in group-I(-1.76 ± 1.00 and-2.54 ± 0.87 respectively). …”
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Combat the growing prevalence of anaemia through underutilised iron-rich plant-based foods by Naman Kaur, Arthittaya Thuanthong, Simran Kaur, Aparna Agarwal, Manisha Sabharwal, Jatinder K. Sahu, Jayashree Arcot, Abhishek Dutt Tripathi, Pankaj Koirala, Nilesh Nirmal

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The Prevalence of Star-forming Clumps as a Function of Environmental Overdensity in Local Galaxies by Dominic Adams, Hugh Dickinson, Lucy Fortson, Kameswara Mantha, Vihang Mehta, Jürgen Popp, Claudia Scarlata, Chris Lintott, Brooke Simmons, Mike Walmsley

“…The resulting sample of 41,445 u -band bright clumps in 34,246 galaxies is the largest sample of clumps yet assembled. …”
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Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study by Aiguo Liu, Aiguo Liu, Ting Ying, Shuang Deng, Chenxu Wang, Chenxu Wang, Ziwen Zhao, Sitong Zhang, Han Xiao, Chengqing Yi, Dejian Li

“…Quartile analysis indicated that participants in the highest ACAG quartile (≥19.55) experienced the most substantial reductions in BMD (β coefficients ranging from −0.034 to −0.036, P < 0.001). Furthermore, a U-shaped relationship was identified, with a turning point at an ACAG value of 22.15, indicating that lower ACAG levels were associated with decreased BMD, while higher levels showed a positive effect. …”
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Comparison of thromboelastographic profiles and clinical characteristics in children with severe Mycoplasma pneumoniae pneumonia by Yong-tao Li, Yu-mei Ma, Fu-li Dai, Zhen Peng, Ya-ping Dai, Ke Zhi, Hai-hong Feng, Shu-jun Li

“…They also showed higher levels of C-reactive protein (median: 30.2 vs. 20.1 mg/L, P < 0.001), lactate dehydrogenase (median: 334.5 vs. 276.0 U/L, P = 0.001), and D-dimer (median: 1.2 vs. 0.5 μg/ml, P < 0.001). …”
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Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals by Sophie Tourdot, Daniel Baltrunkonis, Sofie Denies, Viswanath Devanarayan, Joanna Grudzinska-Goebel, Arno Kromminga, Gregor P. Lotz, Laurent Malherbe, Lydia Michaut, Karin N. Weldingh, Joao A. Pedras-Vasconcelos, Laura. I. Salazar-Fontana, Sebastian Spindeldreher, Zuben Sauna, Veerle Snoeck, Daniela Verthelyi, Daniel Kramer

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O multiculturalismo e as divergências teóricas no debate multicultural by Willian Martini

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Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

“…Feature selection was conducted using the Spearman correlation analysis, Mann–Whitney U-test, and least absolute shrinkage and selection operator (LASSO) regression. …”
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Three-dimensional evaluation of tongue position and volume in adult patients with different skeletal malocclusions by CHIOU Wei-Cho, MEN Xinrui, ZHANG Kaiwen, JIANG Xiaoge, CHEN Song

“…Tongue volume was positively correlated with U1-SN and negatively correlated with overbite and overjet (<i>P </i>&lt; 0.05). …”
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Structural variability of sunflower gene for methionine-rich albumin SFA8 by I. N. Anisimova, N. V. Alpatieva, S. V. Goryunova, D. V. Goryunov, Al. V. Konarev, V. A. Gavrilova, E. E. Radchenko

“…The intron sequences of all accessions contain dinucleotides GT at the 5΄ end and AG at the 3΄ end which are characteristic for consensus sequences of splicing sites in the U2-type introns. The variants of the secondary structure of the SFA8 intron sequences of H. argophyllus Torr. …”
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Prolonged ICU Stay in Severe and Critically-Ill COVID-19 Patients Who Received Convalescent Plasma Therapy by Bambang Pujo Semedi, Nadya Noor Ramadhania, Betty Agustina Tambunan, Siprianus Ugroseno Yudho Bintoro, Soedarsono Soedarsono, Cita Rosita Sigit Prakoeswa

“…Deceased patients, who received convalescent plasma, stayed longer in the ICU with a mean length of stay of 12.87 ± 5.7 days versus 8.13 ± 4.8 days with a significant difference (U = 434; p<0.000). The chance of improved oxygen support requirements was lower in obese patients (aOR = 9.18; 95%CI (2.0, 42.1); p<0.004), mechanically ventilated patients (aOR = 13.15; 95% CI (3.75, 46.09); p<0.001), patients with higher NLR (aOR = 2.5; 95% CI (1.07, 5.85); p=0.034), and lower P/F ratio (aOR = 2.76; 95% CI (1.1, 6.91); p=0.031). …”
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Personality's Time Perspective as a Resource for Overcoming the Identity Crisis at Different Stages of Life Realization by E.M. Meshcheryakova, A.V. Seryy, M.S. Yanitskiy

“…The methods of statistical analysis (correlation analysis, Mann-Whitney U Test, Kruskal&ndash;Wallis test, regression analysis) were used in the processing of the obtained data. …”
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Insights from a Genome-Wide Study of <i>Pantoea agglomerans</i> UADEC20: A Promising Strain for Phosphate Solubilization and Exopolysaccharides Production by Edith Elizondo-Reyna, Humberto Martínez-Montoya, Yahaira Tamayo-Ordoñez, María Antonia Cruz-Hernández, Mauricio Carrillo-Tripp, María Concepción Tamayo-Ordoñez, Gerardo de Jesús Sosa-Santillán, José Antonio Rodríguez-de la Garza, Mario Hernández-Guzmán, Virgilio Bocanegra-García, Erika Acosta-Cruz

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Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation by Tristan Whitmarsh, Wei Cope, Julia Carmona-Bozo, Roido Manavaki, Stephen-John Sammut, Ramona Woitek, Elena Provenzano, Emma L. Brown, Sarah E. Bohndiek, Ferdia A. Gallagher, Carlos Caldas, Fiona J. Gilbert, Florian Markowetz

“…Methods We propose a method for automatically measuring a range of vascular parameters from CD-31 IHC images, which together provide a detailed description of the vasculature morphology. We first used a U-Net based convolutional neural network, trained and validated using 36 partially annotated whole slide images from 27 patients, to segment vessel structures and tumour regions from which the measurements are taken. …”
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Bilateral alterations in sensorimotor function and altered sensory strategy in individuals with unilateral chronic ankle instability by Xiaomei Hu, Xihe Hou, Lin Wang

“…Except for SOT, all tests evaluated bilateral limbs, and the order of limbs was randomly selected. 2 (group) × 2 (limb) mixed model analyses of variance were performed for outcome measures of unilateral stance, Y balance and MCT, and independent t-test was used to analyse the outcomes of SOT between two groups. Mann–Whitney U and Wilcoxon test were applied to examine the differences in plantar sensation between groups and limbs. …”
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Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue by Sara Nava, Valeria Sordi, Luisa Pascucci, Carlo Tremolada, Emilio Ciusani, Offer Zeira, Moris Cadei, Gianni Soldati, Augusto Pessina, Eugenio Parati, Mark Slevin, Giulio Alessandri

“…Similarly, the addition of MFAT-CM recovered at early (3-7 days) and late stage (14-28 days) of culture strongly inhibited inflammatory function of U937 monocyte cell line, whereas the anti-inflammatory activity of LP-CM was drastically reduced after only 7 days of culture. …”
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Well-being balance and lived experiences: understanding the impact of life situations on human flourishing by Christopher R. Brydges, Alexandra Thérond, Troy W. Norris

“…BackgroundThis study aimed to determine the most significant indicators of positive well-being and understand differences in sources of well-being across different life situations, age groups, genders, and income levels, utilizing a novel measure of positive well-being, the Well-being Balance and Lived Experiences (WBAL) Assessment, which evaluates the frequency of various positive experiences and feelings across a range of activation and arousal levels that have previously been demonstrated to affect subjective well-being and human flourishing.MethodsA sample of 496 evaluable subjects aged 20-69 and census-balanced for gender were recruited from a U.S. population panel. Differences in well-being and sources of well-being were analyzed across subgroups via MANOVA analysis followed by post-hoc ANOVA and Tukey’s HSD analyses using Cohen’s d to determine size and direction of effects between categorical subgroups.ResultsLife situations, including relationship, parenting and employment status, were shown to have a more significant effect on overall well-being than the demographic variables of age, gender and household income. …”
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Neoplasms in the Nasal Cavity Identified and Tracked with an Artificial Intelligence-Assisted Nasal Endoscopic Diagnostic System by Xiayue Xu, Boxiang Yun, Yumin Zhao, Ling Jin, Yanning Zong, Guanzhen Yu, Chuanliang Zhao, Kai Fan, Xiaolin Zhang, Shiwang Tan, Zimu Zhang, Yan Wang, Qingli Li, Shaoqing Yu

“…Methods: We retrospectively analyzed 1050 video data of nasal endoscopic surgeries involving four types of nasal neoplasms. Using Deep Snake, U-Net, and Att-Res2-UNet, we developed a nasal neoplastic detection network based on endoscopic images. …”
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Capsaicin Modulates Ruminal Fermentation and Bacterial Communities in Beef Cattle with High-Grain Diet-Induced Subacute Ruminal Acidosis by Wei You, Haijian Cheng, Xin Hu, Enliang Song, Fugui Jiang

“…The unique genera associated with the CON group included <i>Rikenellaceae_RC9_gut_group</i>, <i>Prevotellaceae_UCG-003</i>, and <i>U29-B03</i>, while those for the CAP group included <i>Succiniclasticum</i> and <i>Prevotellaceae_UCG-004</i>. …”
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