Multiomic quantification of the KRAS mutation dosage improves the preoperative prediction of survival and recurrence in patients with pancreatic ductal adenocarcinoma by Won-Gun Yun, Daeun Kim, Youngmin Han, Wooil Kwon, Seong-Geun Lee, Jin-Young Jang, Daechan Park

“…Our prognostic scoring system included the mutation dosage from targeted sequencing ( > 0.195, 1 point), maximal tumor diameter at preoperative imaging ( > 20 mm, 1 point), and carbohydrate antigen 19-9 levels ( > 150 U/mL, 1 point). The KRAS mutation dosage exhibited comparable performance with clinical variables for survival prediction. …”
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Self-Management Education for Persons with Parkinson’s Disease and Their Care Partners: A Quasi-Experimental Case-Control Study in Clinical Practice by Carina Hellqvist, Carina Berterö, Nil Dizdar, Märta Sund-Levander, Peter Hagell

“…Descriptive statistics were used to describe baseline characteristics. Mann–Whitney U and Chi2 tests were used to test for between-group differences and within-group differences were tested by the Wilcoxon signed-ranks test. …”
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Identifying the Geographical Origin of Tobacco Leaf by Strontium and Lead Isotopic with Mineral Elemental Fingerprint by Liu Hong, Wenyuan Wang, Yang Su, Guiping Zhang, Yong Su, Chenming Zhang, Jianhua Chen, Wei Zhe, Zhihua Liu, Jianyong Cui, Deshou Mao, Jin Wang

“…We collected eighty-one tobacco leaf samples from Argentina, Brazil, Zimbabwe, the U.S., Zambia, and China. And nine mineral element contents and four strontium and lead isotope ratios of the tobacco leaves were determined by thermal ionization mass spectrometry (TIMS) and inductively coupled plasma mass spectrometry (ICP-MS). …”
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Occupational health risk assessment and risk monetization based on xylene exposureMendeley Data by Fei Li, Boshen Wang, Baoli Zhu

“…In this study, a number of xylene-related companies in seven industries from 2020 to 2023 were collected as research subjects, and the health risks caused by xylene exposure were evaluated using the EPA model designated by the U.S. Environmental Protection Agency, the Singapore Semi-Quantitative Risk Assessment Model (MOM), and the International Council on Mining and Metals (ICMM) Occupational Health Risk Assessment Model. …”
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Influence of flavonoids’ lipophilicity on platelet aggregation by Babić Ivana, Bojić Mirza, Maleš Željan, Zadro Renata, Gojčeta Koraljka, Duka Ivan, Rimac Hrvoje, Jukić Irena

“…Platelet membrane stabilization by flavonoids as a mechanism of antiaggregatory effect has been supported by impedance aggregometry experiments when specific inhibitors of platelet aggregation signaling pathways (U73122, indomethacin, verapamil) were used in the presence of a weak (ADP) and a strong (TRAP-6) agonist of aggregation. …”
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Serial cerebrospinal fluid concentrations of high mobility group box 1 in bacterial meningitis: a retrospective cohort study by Takeshi Matsushige, Hirofumi Inoue, Madoka Hoshide, Fumitaka Kohno, Hikaru Kobayashi, Kiyoshi Ichihara, Takashi Ichiyama, Shunji Hasegawa

“…Statistical analyses included Mann–Whitney U tests, Kruskal–Wallis tests, and three-way ANOVA to evaluate differences among groups and over time. …”
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Des vestiges liés à la phase de construction de l’aqueduc de la Brévenne à Limonest (Métropole de Lyon) ? by Stéphane Ardouin, Cécile André-Chaze

“…Two straight ditches were revealed, running perpendicular to the trunk of the aqueduct pipe and on both sides of a slight bend formed by the pipeline.Observed over a distance of 16 m (in the case of the longest ditch), but probably longer in all, these ditches have a U-shaped profile with a flat bottom and vertical sides, measuring approximately 37 cm in width. …”
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A Multiwavelength Light-curve Analysis of the Classical Nova KT Eri: Optical Contribution from a Large Irradiated Accretion Disk by Izumi Hachisu, Mariko Kato, Frederick M. Walter

“…Recent photometric analysis in quiescence indicates a relatively longer orbital period of 2.6 days, so that KT Eri could host a very bright accretion disk during the outburst like in the recurrent nova U Sco, the orbital period of which is 1.23 days. …”
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Cost-effectiveness analysis of durvalumab with chemotherapy and maintenance durvalumab with or without olaparib for advanced endometrial cancer by Jiahao Zhang, Jianying Lei, Caicong You, Wu Fu, Bin Zheng, Hongfu Cai, Maobai Liu, Na Li

“…CT) and $416,098.68/QALYs (DCT vs. CT). From a U.S. payer perspective, DOCT and DCT regimens are not cost-effective compared to CT for advanced or recurrent EC, including dMMR and pMMR subgroups, at a $150,000/QALY threshold.…”
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IL-10 and ARG-1 Concentrations in Bone Marrow and Peripheral Blood of Metastatic Neuroblastoma Patients Do Not Associate with Clinical Outcome by Fabio Morandi, Michela Croce, Giuliana Cangemi, Sebastiano Barco, Valentina Rigo, Barbara Carlini, Loredana Amoroso, Vito Pistoia, Silvano Ferrini, Maria Valeria Corrias

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A Low-Complexity Diversity-Preserving Universal Bit-Flipping Enhanced Hard Decision Decoder for Arbitrary Linear Codes by Praveen Sai Bere, Mohammed Zafar Ali Khan, Lajos Hanzo

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Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex by Harald Bernhard, Hana Petržílková, Barbora Popelářová, Kamil Ziemkiewicz, Karolina Bartosik, Marcin Warmiński, Laura Tengo, Henri Gröger, Luciano G. Dolce, Cameron D. Mackereth, Ronald Micura, Jacek Jemielity, Eva Kowalinski

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Associations between phenol and paraben exposure and the risk of developing breast cancer in adult women: a cross-sectional study by Yao Xiong, Zhiyu Li, Xiong Xiong, Zixuan Luo, Kaixin Zhong, Jiawei Hu, Shengrong Sun, Chuang Chen

“…The nonlinear association between TRS concentrations and the risk of developing BC was statistically significant (P nonlinear = 0.007), with the restricted cubic splines (RCS) curve exhibiting an inverted U shape. The association between TRS concentrations and the risk of developing BC was more pronounced among overweight individuals (BMI ≥ 25 kg/m2), those aged < 60 years, and white individuals. …”
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Characterization of Residential Woodsmoke PM2.5 in the Adirondacks of New York by George Allen, Lisa Rector

“…Despite these PM events, the data indicated that this location was likely in compliance with the current U.S. EPA National Ambient Air Quality Standards (NAAQS) for PM2.5. …”
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Lower electronic health record adoption and interoperability in rural versus urban physician participants: a cross-sectional analysis from the CMS quality payment program by A. Jerrod Anzalone, Carol R. Geary, Ran Dai, Shinobu Watanabe-Galloway, James C. McClay, James R. Campbell

“…Abstract Background The Health Information Technology for Economic and Clinical Health Act of 2009 introduced the Meaningful Use program to incentivize the adoption of electronic health records (EHRs) in the U.S. This study investigates the disparities in EHR adoption and interoperability between rural and urban physicians in the context of federal programs like the Medicare Access and CHIP Reauthorization Act of 2015 and the 21st Century Cures Act. …”
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Práticas de marketing interno na instituição de ensino by Aléssio Bessa Sarquis, Osvair Almeida Matos, João Coelho Soares, Glauco José Ribeiro Borges, Aldus Marcelo da Silva Nascimento

“…A coleta de dados aconteceu por meio de questionário autoadministrado e os dados foram analisados com auxílio de técnicas de estatísticas descritivas, Cluster Analysis e teste U de Mann Whitney. Resultados apontam que as práticas de marketing interno mais utilizadas são: desenvolvimento de cultura organizacional e de ensino; relacionamento instituição funcionários; integração/diálogo entre coordenadores e docentes; uso de canais de comunicação interna e desenvolvimento do clima organizacional. …”
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İBNİ RÜŞD'DE DİN-FELSEFE İLİŞKİSİ BAĞLAMINDA SİYASET by Lokman Çilingir

“…Bu makale, Ortaçağın sonlarında doğal gelişimini tamamlayan bir medeniyetin en uç noktasında son demlerini yaşayan bir ülkede, Endülüs’te yetişmiş, gerek din bilimlerinde gerekse tıp ve felsefe alanlarında iyi bir eğitim almış, kadılık ve baştabiplik görevlerinde bulunmuş, yönetime yakın durmuş, iktidarın siyasi projesinin bir parçası olmuş ama aynı zamanda iktidar kavgaları arasında kurban olma tehlikesini her an ensesinde hissetmiş bir düşünür olan İbni Rüşd’ü siyasi açıdan konumlandırmayı; onun din-felsefe ilişkisi bağlamında siyaseti çözümleyişini eleştirel açıdan gözden geçirmeyi amaçlamaktadır.Grek düşünürler siyaseti tartışırken önerilerinde, siyasetten, ekonomiye, inançtan eğitime tüm toplum yaşamını kuşatan şehir devleti(Polis) dururken, klasik İslam düşünürleri önünde Şer’i yasalar ve İslam Devleti duruyordu. …”
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Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases by Benoit Le Goff, Béatrice Bouvard, Thierry Lequerre, Eric Lespessailles, Hubert Marotte, Yves-Marie Pers, Bernard Cortet

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Resistance Distance in Tensor and Strong Product of Path or Cycle Graphs Based on the Generalized Inverse Approach by Muhammad Shoaib Sardar, Xiang-Feng Pan, Dalal Alrowaili, Imran Siddique

“…The resistance distance among two vertices u and v of a graph G is determined as the effective resistance among the two vertices when a unit resistor replaces each edge of G. …”
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Raised Serum Adenosine Deaminase Level in Nonobese Type 2 Diabetes Mellitus by Vineet Kumar Khemka, Debajit Bagchi, Arindam Ghosh, Oishimaya Sen, Aritri Bir, Sasanka Chakrabarti, Anindita Banerjee

“…Serum ADA level was found significantly higher among nonobese T2DM subjects with respect to controls (38.77±14.29 versus 17.02±5.74 U/L; P<0.0001). Serum ADA level showed a significant positive correlation with fasting plasma glucose (r=0.657; P<0.0001) level among nonobese T2DM subjects, but no significant correlation was observed in controls (r=-0.203; P=0.180). …”
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