Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome by P. Stiefel, A. J. Vallejo-Vaz, S. García Morillo, J. Villar

“…Finally, overweight and obesity promote the adrenal secretion of aldosterone, increasing the predisposition to type 2 diabetes mellitus. Further studies are needed to better establish therapeutic strategies that act on the blockade of mineralocorticoid receptor in the treatment and prevention of cardiovascular diseases related to the excess of aldosterone and the metabolic syndrome.…”
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Advances in Murine Models of Diabetic Nephropathy by Li-li Kong, Hao Wu, Wen-peng Cui, Wen-hua Zhou, Ping Luo, Jing Sun, Hang Yuan, Li-ning Miao

“…Diabetic nephropathy (DN) is one of the microvascular complications of both type 1 and type 2 diabetes, which is also associated with a poor life expectancy of diabetic patients. …”
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The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders by Elisa Benetti, Fausto Chiazza, Nimesh S. A. Patel, Massimo Collino

“…The combination of obesity and type 2 diabetes is a serious health problem, which is projected to afflict 300 million people worldwide by 2020. …”
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Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume in patients with diabetic retinopathy by Trisha Ghosh, Sanjay Kumar Daulat Thakur, Premangshu Ghosh, Trina Sengupta

“…Materials and Methods: A cross-sectional study was conducted among 60 patients with a definite diagnosis of type 2 diabetes mellitus attending the ophthalmology outpatient department of a tertiary care hospital. …”
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A multidimensional study for design of phytochemical profiling, antioxidant potential, and enzyme inhibition effects of ışgın (Rheum telianum) as an edible plant by Ahmet Zafer Tel, Kubra Aslan, Mustafa Abdullah Yılmaz, İlhami Gulcin

“…The inhibition effects of both leaves and the seeds of the R. telianum extracts on acetylcholinesterase and butyrylcholinesterase, α-glycosidase and human carbonic anhydrases II isoenzyme enzymes, which associated with some global diseases including Alzheimer's disease, type-2 diabetes mellitus and glaucoma were determined. …”
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The impact of tuberculosis-induced hyperglycemia on pulmonary microbiota and airway mucus secretion in individuals not previously diabetic: A systematic review and meta-analysis pr... by Victor Moses Musyoki, Marianne Mureithi, Annamari Heikinheimo, Elizabeth Maleche-Obimbo, Kariuki Njaanake, Omu Anzala

“…Infection with Mycobacterium tuberculosis, psychological stress associated with the tuberculosis (TB) disease, and the metabolites from the rifampicin treatment regimen have been reported to induce hyperglycemia and consequently type 2 diabetes mellitus (T2DM) in individuals not previously diabetic. …”
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Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy by Axel H. Schönthal

“…For example, obesity and type 2 diabetes have been linked to ER stress-induced failure of insulin-producing pancreatic beta cells, and current research efforts are aimed at developing drugs that ameliorate cellular stress and thereby protect beta cell function. …”
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Antidiabetic Potential of Marine Brown Algae—a Mini Review by Thilina L. Gunathilaka, Kalpa Samarakoon, Pathmasiri Ranasinghe, L. Dinithi C. Peiris

“…Therefore, in lieu with herbal drug development, it is important to find the potential benefits of seaweeds for the management of type 2 diabetes as they are underexplored yet in Sri Lanka. …”
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Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNAThr Gene by Ke Li, Lijun Wu, Jianjiang Liu, Wei Lin, Qiang Qi, Tianlan Zhao

“…We report here the clinical, genetic, and molecular characteristics of type 2 diabetes in a Chinese family. There are differences in the severity and age of onset in diabetes among these families. …”
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Metformin and Fibrosis: A Review of Existing Evidence and Mechanisms by Maoyan Wu, Huiwen Xu, Jingyu Liu, Xiaozhen Tan, Shengrong Wan, Man Guo, Yang Long, Yong Xu

“…Metformin, which is a potent AMPK activator and is the only recommended first-line drug for the treatment of type 2 diabetes, has emerged as a promising method of fibrosis reduction or reversion. …”
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Lay Health Trainers Supporting Self-Management amongst Those with Low Heath Literacy and Diabetes: Lessons from a Mixed Methods Pilot, Feasibility Study by Bernadette Bartlam, Trishna Rathod, Gillian Rowlands, Joanne Protheroe

“…This article reports a mixed methods process evaluation of a pilot feasibility randomised controlled trial comparing a Lay Health Trainer (LHT) intervention and usual care for those with poorly controlled Type 2 Diabetes Melitus (T2DM). Set in a deprived area in the UK, this research explores patient and health care practitioner (HCP) views on whether a structured interview between a patient and a Lay Health Trainer (LHT), for the purpose of developing a tailored self-management plan for patients, is acceptable and likely to change health behaviours. …”
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Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases by Min Kyung Sung, Hyoeun Bang, Jung Kyoon Choi

“…In this work, we studied epistatic interactions associated with three common diseases using Korea Association Resource (KARE) data: type 2 diabetes mellitus (DM), hypertension (HT), and coronary artery disease (CAD). …”
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Poor control of oxidative stress index is associated with increased DNA methylation in retinopathy patients of a sample from babylonian population by Farah A. Al-Hassan, Hawraa Sabah Al-Musawi

“…Materials and Methods: The study included 120 participants, of whom 40 were healthy, 40 patients with retinopathy, and 40 non-retinopathy diabetes patients (type 2 diabetes mellitus (T2DM)). The total antioxidant, capacity (TAC) evaluated using Cupric ion reducing antioxidant capacity method. …”
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Yoga practices effect on VCSS-based classification of patients with chronic venous insufficiency based on hybrid machine learning algorithms by Changhong Pan, Lu Qi, Lili Zhao, Yijun Wei

“…Non-pharmacological approaches like yoga are gaining popularity for stress management, showing positive effects on the autonomic nervous system and offering benefits such as improved cardio-respiratory health and metabolic efficiency, as well as positive effects on conditions like Type-2 diabetes, Chronic Venous Disease (CVD), and obesity. …”
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The Expression of miR-192 and Its Significance in Diabetic Nephropathy Patients with Different Urine Albumin Creatinine Ratio by Xiaoyu Ma, Canlu Lu, Chuan Lv, Can Wu, Qiuyue Wang

“…Methods. 464 patients with type 2 diabetes mellitus (T2DM) were divided into normal albuminuria group (NA, n=157), microalbuminuria group (MA, n=159), and large amount of albuminuria group (LA, n=148). 127 healthy persons were selected as the control group (NC, n=127). …”
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Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque by Tingfu Du, Shuaiyao Lu, Qinfang Jiang, Yun Li, Kaili Ma

“…Type 2 diabetes mellitus (T2DM) is a metabolic disorder that severely affects human health, but the pathogenesis of the disease remains unknown. …”
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Microbiota for production of wine with enhanced functional components by Armachius James, Ting Yao, Hengming Ke, Yousheng Wang

“…Moderate wine consumption, particularly red wine has been associated with functional benefits to human health, which includes anti-inflammation, promoting healthy aging, prevention of cardiovascular diseases, cancers, type 2 diabetes and metabolic syndrome. Indeed, the management of microbiota allows the production of wine with distinct features and functional components that benefits human health. …”
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Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro by Ting Li, Ting Fang, Linxin Xu, Xiangyang Liu, Xiaoyu Li, Mei Xue, Xiaochen Yu, Bei Sun, Liming Chen

“…Background: Metabolic associated fatty liver disease (MAFLD), characterized by hepatic lipid accumulation and fatty degeneration, is intertwined with obesity and type 2 diabetes mellitus (T2DM). Empagliflozin is a sodium-glucose cotransporter-2 inhibitor that effectively lowers blood glucose, but its effect on MAFLD and associated mechanisms are not fully understood.Methods: Eight-week-old db/db mice, an in vivo model, were administered empagliflozin or saline intragastrically. …”
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The Food Resources and Kitchen Skills intervention: Protocol of a randomized controlled trial. by Armando Peña, Emily Dawkins, Mariah Adams, Lyndsi R Moser, Amy Carter, Rebecca L Rivera, Deanna Reinoso, Wanzhu Tu, Richard J Holden, Daniel O Clark

“…<h4>Introduction</h4>Individuals with food insecurity are disproportionately burdened by hypertension (HTN) and type 2 diabetes and face greater barriers to self-managing these conditions.…”
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The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review. by Tiscar Graells, Yi-Ting Lin, Shafqat Ahmad, Tove Fall, Johan Ärnlöv

“…In total, the urobiome of 1,571 people was sequenced, of which 662 people had diabetes, and of these 36 had confirmed diabetic kidney disease; 609 were healthy individuals, 179 had prediabetes or were at risk of type 2 diabetes mellitus and 121 did not have diabetes but had other comorbidities. …”
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