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1261
Rehabilitative Treatment as an Alternative in Amputee Patients. Case Report and Literature Review
Published 2023-11-01“…The case of a 52-year-old male patient is presented, with a history of type 2 diabetes mellitus and arterial hypertension controlled by treatment, in addition to suffering from hereditary thrombopathy treated with anticoagulants, which is why he underwent surgical treatment. …”
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1262
Virtual Screening as a Technique for PPAR Modulator Discovery
Published 2010-01-01“…It is well recognized that PPARγ agonists have therapeutic applications as insulin sensitizers in type 2 diabetes or as anti-inflammatories. VS is a cost- and time-effective means for identifying small molecules that have therapeutic potential. …”
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1263
JAK inhibitors: a new choice for diabetes mellitus?
Published 2025-01-01“…Recently, several clinical cases involving the reversal of type 1 diabetes mellitus (T1DM) during treatment with JAK inhibitors have been reported, and clinical studies have described the improvement of type 2 diabetes mellitus (T2DM) during treatment with JAK inhibitors. …”
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1264
Diagnosis of a Morgagni-Stewart-Morel Syndrome in a Patient with Ischemic Stroke. Report of a Case
Published 2022-01-01“…The case of a 77-year-old patient with a history of type 2 diabetes mellitus, systemic arterial hypertension and psychiatric disorder, who was admitted to the Neurology Service of the Dr. …”
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1265
Spatiotemporal Regulators for Insulin-Stimulated GLUT4 Vesicle Exocytosis
Published 2017-01-01“…Importantly, the dysfunction of insulin-regulated GLUT4 trafficking is strongly linked with peripheral insulin resistance and type 2 diabetes in human. The insulin signaling pathway, key signaling molecules involved, and precise trafficking itinerary of GSVs are largely identified. …”
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1266
Ozone therapy as support in the treatment of diabetic foot ulcer. A case report
Published 2023-07-01“…The case of a 43-years-old patient with a diagnosis of type 2 diabetes mellitus, of seven years of evolution, referred from the Emergency Department of the Dr. …”
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1267
Metformin: A Possible Option in Cancer Chemotherapy
Published 2020-01-01“…Metformin has been used for a long time as an antidiabetic medication for type 2 diabetes. It is used either as a monotherapy or in combination with other antidiabetic medications. …”
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1268
Physical Activity and Arterial Stiffness: A Narrative Review
Published 2025-01-01“…These benefits are especially significant in populations with higher cardiovascular risk, such as those with type 2 diabetes mellitus and hypertension. Therefore, maintaining an active lifestyle into older age is crucial for vascular health and may contribute to healthy aging.…”
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1269
Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome
Published 2017-01-01“…Her parents are cousins and the mother was diagnosed with type 2 diabetes. She had negative autoantibodies and no signs of insulin resistance and her monogenic diabetes genetic testing was negative. …”
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1270
Methods and Models for Metabolic Assessment in Mice
Published 2013-01-01“…The development of new therapies for the treatment of type 2 diabetes requires robust, reproducible and well validated in vivo experimental systems. …”
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1271
Interorgan Crosstalk Contributing to β-Cell Dysfunction
Published 2017-01-01“…Type 2 diabetes mellitus (T2DM) results from pancreatic β-cell failure in the setting of insulin resistance. …”
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1272
Acorn Oil: Chemistry and Functionality
Published 2020-01-01“…Diets enriched with acorn oil can be beneficial in preventing cardiovascular disease (CVD), cancer, and type 2 diabetes as well as offer antioxidant activity. …”
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1273
Brown fat thermogenesis and branched-chain amino acids in metabolic disease
Published 2024-02-01“…Since the 1960s, researchers have recognized an association between elevated plasma branched chain amino acids (BCAA) and metabolic disease, including type 2 diabetes mellitus and obesity, but the cause for it remained poorly understood. …”
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1274
A Patient with Chronic Lymphocytic Leukemia with Pancreatic Involvement
Published 2019-01-01“…A 78-year-old female with a past medical history of hypertension, type 2 diabetes mellitus, and chronic lymphocytic leukemia was hospitalized for poor appetite, weight loss, and night sweats. …”
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1275
Regulation of Metabolic Disease-Associated Inflammation by Nutrient Sensors
Published 2018-01-01“…Visceral obesity is frequently associated with the development of type 2 diabetes (T2D), a highly prevalent chronic disease that features insulin resistance and pancreatic β-cell dysfunction as important hallmarks. …”
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1276
Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis
Published 2025-01-01“…Additionally, the role of type 2 diabetes mellitus (T2DM) and heart failure (HF) in modulating the effectiveness of these drugs post-MI are not fully understood. …”
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1277
Dynamics of endothelial function in patients with arterial hypertension with different cardiovascular risk against the background of antihypertensive therapy
Published 2024-10-01“…The obtained results testify to the dominant role of type 2 diabetes as a factor in platelet disorders of hemostasis. …”
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1278
Open challenges for the automatic synthesis of clinical trials
Published 2025-02-01“…To address this challenge, we utilized our annotated dataset, which includes 211 abstracts of clinical trials related to glaucoma and type 2 diabetes mellitus. We then developed a tool that provides an overview of the annotated clinical trial information and enables users to group them by outcomes. …”
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1279
Neuroimmune axis: Linking environmental factors to pancreatic β-cell dysfunction in Diabetes
Published 2025-02-01“…Pancreatic β-cells are specialized in secreting insulin in response to circulating nutrients, mainly glucose.Diabetes is one of the most prevalent endocrine-metabolic diseases characterized by an imbalance in glucose homeostasis, which result mainly from lack of insulin production (type 1 diabetes) or insufficient insulin and peripheral insulin resistance (type 2 diabetes), both influenced by genetic and environmental components. …”
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1280
Junctional Bradikardia pada Pasien Hiperkalemia
Published 2021-09-01“…It has been reported that a 76 years old woman with type 2 diabetes mellitus, hyperkalemia and suspected coronary artery disease complaining about palpitation. …”
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